Treximet Shortage Update: What Patients Need to Know in 2026

Updated:

February 15, 2026

Author:

Peter Daggett

Summarize this blog with AI:

Is Treximet in shortage in 2026? Get the latest update on Treximet availability, pricing, and what to do if you can't find it at your pharmacy.

Is Treximet in Shortage in 2026?

If you've had trouble finding Treximet (Sumatriptan/Naproxen Sodium) at your local pharmacy, you're probably wondering: is there a shortage? The short answer is no — Treximet is not on the FDA's official drug shortage list. But that doesn't mean it's easy to find.

Many patients report difficulty getting Treximet filled at chain pharmacies, and the reasons have more to do with economics and pharmacy stocking decisions than with manufacturing problems. In this article, we'll break down the current situation and what you can do about it.

Why Is Treximet Hard to Find?

Even without a formal shortage, several factors make Treximet difficult to locate:

Limited Pharmacy Stocking

Treximet is a niche combination product. Most pharmacies stock high-volume generics like standalone Sumatriptan, but few keep the combination tablet on their shelves. When a medication isn't in regular demand at a particular location, pharmacies simply don't order it.

High Cost Reduces Demand

Brand-name Treximet costs $500 to $900 for 9 tablets at retail. Even the generic runs $130 to $250 for 9 tablets with a discount card. Many patients and doctors opt for the cheaper approach of taking Sumatriptan and Naproxen Sodium as two separate pills, which further reduces demand for the combination product.

Insurance Barriers

Insurance companies often require prior authorization or step therapy before covering Treximet. That means patients may need to try (and fail on) a standalone triptan before their plan will pay for the combination. These barriers slow down the prescription pipeline and make pharmacies even less likely to stock it.

Discontinued Pediatric Formulation

The lower-dose Treximet formulation (10 mg Sumatriptan / 60 mg Naproxen Sodium), originally approved for adolescents, has been discontinued. Only the adult 85/500 mg tablet remains available.

For a deeper look at the reasons behind availability issues, see our article on why Treximet is so hard to find.

How Much Does Treximet Cost in 2026?

Here's a breakdown of current pricing:

  • Brand-name Treximet: $500 to $900 for 9 tablets (retail without insurance)
  • Generic Sumatriptan/Naproxen Sodium: Starting around $130 for 9 tablets with a GoodRx or SingleCare coupon
  • Direct from manufacturer (treximet.com): $75 for 9 authorized generic tablets or $99 for brand-name, with free shipping

If cost is a barrier, check out our full guide on how to save money on Treximet.

Are There New Options for Migraine Treatment?

The migraine treatment landscape has expanded in recent years. If you're having trouble with Treximet availability, talk to your doctor about:

  • CGRP receptor antagonists (gepants) like Ubrogepant (Ubrelvy) and Rimegepant (Nurtec ODT) — these are newer oral medications that work differently from triptans and don't carry cardiovascular risks
  • Other triptans like Rizatriptan (Maxalt) or Eletriptan (Relpax) paired with over-the-counter Naproxen Sodium
  • CGRP preventive medications like Erenumab (Aimovig) or Galcanezumab (Emgality) for patients with frequent migraines

Learn more about your options in our guide to alternatives to Treximet.

How to Find Treximet in Stock

If you want to stick with Treximet, here's how to get it:

  1. Use Medfinder to check which pharmacies near you have it in stock right now
  2. Try independent pharmacies — they're often more willing to special-order medications
  3. Order from treximet.com — the manufacturer ships directly to patients with a valid prescription
  4. Plan ahead — refill early and request your pharmacy order it in advance

For detailed tips, read our guide on how to find Treximet in stock near you.

Final Thoughts

Treximet is not in a formal shortage, but real-world availability remains a challenge in 2026. The combination of high cost, insurance hurdles, and low pharmacy demand creates a perfect storm for patients who rely on this medication. Stay proactive — use Medfinder to track availability, explore discount options, and keep an open conversation with your doctor about backup plans.

If you're a healthcare provider looking for resources, see our provider-focused update on what prescribers need to know about Treximet availability in 2026.

Is Treximet on the FDA shortage list?

No. As of early 2026, Treximet (Sumatriptan/Naproxen Sodium) is not listed on the FDA drug shortage database. Availability problems are related to pharmacy stocking decisions and cost barriers, not manufacturing shortages.

How much does Treximet cost without insurance in 2026?

Brand-name Treximet costs $500 to $900 for 9 tablets at retail. The generic starts around $130 for 9 tablets with a discount coupon. You can also order the authorized generic directly from treximet.com for $75 for 9 tablets.

Is the Treximet pediatric formulation still available?

No. The pediatric formulation of Treximet (10 mg Sumatriptan / 60 mg Naproxen Sodium) has been discontinued. Only the adult strength (85 mg Sumatriptan / 500 mg Naproxen Sodium) is currently available.

What should I do if my pharmacy says Treximet is backordered?

Try using Medfinder to check stock at other pharmacies nearby. Independent pharmacies are often more flexible with ordering. You can also order directly from the manufacturer at treximet.com, or ask your doctor about taking Sumatriptan and Naproxen Sodium as two separate medications.

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