Treximet can cost $500+ without insurance. Learn how to save with coupons, discount cards, manufacturer programs, and patient assistance in 2026.
If you've ever looked at the price tag on a Treximet prescription, you know it's not cheap. Brand-name Treximet (Sumatriptan 85 mg / Naproxen Sodium 500 mg) can cost $500 to $900 for just 9 tablets without insurance. Even with insurance, copays can be steep because many plans place it on higher formulary tiers.
The good news? There are several ways to bring the cost down significantly — in some cases by hundreds of dollars. In this guide, we'll walk through every option available in 2026.
Here's what you can expect to pay at retail without any insurance or discounts:
These prices vary by pharmacy and location, but the bottom line is clear: Treximet is one of the more expensive migraine medications on the market. That's partly because it's a patented combination product and partly because there's limited generic competition.
Prescription discount cards are one of the fastest ways to lower your out-of-pocket cost for generic Treximet. These are free to use and work even if you have insurance (though they can't be combined with insurance — you use one or the other).
How to use them: Visit the discount card website, search for "Sumatriptan/Naproxen Sodium," enter your zip code, and compare prices at pharmacies near you. Show the coupon (on your phone or printed) to the pharmacist when you pick up your prescription.
Pro tip: Prices can vary by $50 to $100+ between pharmacies for the same medication. Always compare at least 3 to 4 locations before choosing where to fill.
Currax Pharmaceuticals, the maker of Treximet, offers a direct-to-patient program through their website:
This is often the best deal available for Treximet, even cheaper than most discount card prices. To use it:
If your insurance covers Treximet, the manufacturer's program can also help look up your coverage and submit claims, potentially lowering your cost even further.
If you're uninsured or underinsured and struggling to afford your medications, patient assistance programs may be able to help:
NeedyMeds is a nonprofit that maintains a database of patient assistance programs, discount drug cards, and other resources for people who can't afford their medications. Search for Treximet or Sumatriptan/Naproxen to see available programs.
RxAssist offers a comprehensive database of patient assistance programs from pharmaceutical companies, government agencies, and nonprofits.
RxHope helps connect patients with manufacturer-sponsored assistance programs and other savings opportunities.
Eligibility for these programs typically depends on income level, insurance status, and other factors. Application processes vary but usually require documentation from your prescriber.
If your doctor prescribed brand-name Treximet, ask if the generic (Sumatriptan/Naproxen Sodium) is an option. Most pharmacies will automatically substitute the generic unless the prescription specifies "dispense as written," but it's worth confirming. The generic can save you $300 to $700 per fill compared to brand.
The most dramatic savings come from taking Sumatriptan and Naproxen Sodium as two separate medications instead of the combination tablet:
That's a savings of over $100 compared to even the cheapest generic Treximet option. Ask your doctor if this approach is right for you. For more details, see our guide to alternatives to Treximet.
If you're on Medicare, check whether your Part D plan covers generic Sumatriptan/Naproxen Sodium. Coverage and copay tiers vary by plan. Even with Medicare coverage, a discount card may sometimes offer a lower price — compare both options.
Pharmacy prices for the same medication can vary dramatically. Use Medfinder to find pharmacies that stock Treximet near you, then compare prices using GoodRx or SingleCare at each location. Warehouse pharmacies like Costco often have competitive pricing (you don't need a Costco membership to use the pharmacy).
Nobody should have to skip a migraine medication because of cost. Between manufacturer programs, discount cards, patient assistance, and the option to take ingredients separately, there are real ways to make Treximet — or its equivalent — affordable.
Start with the manufacturer's direct program at treximet.com ($75 for 9 generic tablets), compare discount card prices, and talk to your doctor about whether separate Sumatriptan and Naproxen is a viable option for you. And if finding the medication itself is the challenge, use Medfinder to check pharmacy stock near you.
For more on availability, see our articles on how to find Treximet in stock and the latest Treximet shortage update.
You focus on staying healthy. We'll handle the rest.
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