Comprehensive medication guide to {drug} including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Xofluza (Baloxavir Marboxil) is a prescription antiviral medication used to treat acute uncomplicated influenza (the flu) in patients aged 5 years and older who have been symptomatic for no more than 48 hours. It is also approved for post-exposure prophylaxis — meaning it can help prevent the flu after close contact with someone who is infected. The 80 mg dose pack is specifically intended for patients weighing 80 kg (approximately 176 lbs) or more. Unlike older flu medications that require multiple doses over several days, Xofluza is taken as a single oral dose, making it one of the most convenient treatment options available.
Xofluza works through a unique mechanism of action that is different from older flu antivirals like Tamiflu (Oseltamivir). It belongs to a class called cap-dependent endonuclease inhibitors. Xofluza targets the influenza virus's polymerase acidic (PA) endonuclease protein, which the virus needs to replicate its genetic material. By blocking this enzyme, Xofluza stops the virus from multiplying at the source. This mechanism means Xofluza attacks the flu virus at an earlier stage of replication compared to neuraminidase inhibitors, potentially reducing the duration and severity of symptoms more quickly.
Xofluza 80 Mg Dose Pack receives a findability score of 55 out of 100, placing it in the moderate range. While Xofluza is not currently listed as in shortage by the FDA, availability can fluctuate significantly during peak flu season when demand surges. Pharmacies may run low on stock during severe flu seasons, particularly in winter months. Because Xofluza is a single-dose treatment prescribed within 48 hours of symptom onset, timing is critical — if your local pharmacy is out of stock, you may need to act quickly to find it elsewhere before the treatment window closes.
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Xofluza is commonly prescribed by primary care physicians, family medicine doctors, internal medicine specialists, and pediatricians. It is also frequently prescribed in urgent care clinics and emergency departments, where patients often present with acute flu symptoms. Infectious disease specialists and pulmonologists may prescribe it for patients at high risk of influenza-related complications. Xofluza is also available through telehealth providers, which can be a convenient option when you're feeling too ill to visit a doctor's office in person.
No, Xofluza is not a controlled substance. It does not have a DEA schedule classification, which means it does not carry the same prescribing restrictions as medications with abuse potential. However, Xofluza still requires a prescription from a licensed healthcare provider — it is not available over the counter.
Xofluza 80 Mg Dose Pack offers a convenient single-dose treatment for influenza, making it an attractive option for patients who want to avoid a multi-day medication regimen. While the cash price can be steep at $200–$280, Genentech's savings programs can bring costs down significantly — as low as $35 with insurance or $50 through their direct-to-patient program. During peak flu season, availability may be limited at some pharmacies, so if your doctor prescribes Xofluza, it's worth checking stock at multiple locations or using Medfinder to locate it quickly. Remember that Xofluza must be taken within 48 hours of symptom onset to be effective, so time is of the essence.
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