Comprehensive medication guide to {drug} including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Oseltamivir (brand name Tamiflu) is an antiviral medication used to treat and prevent influenza A and B. It belongs to a class of drugs called neuraminidase inhibitors. The FDA has approved oseltamivir for treating acute, uncomplicated flu in patients 2 weeks and older who have been symptomatic for no more than 48 hours, and for flu prevention (prophylaxis) in patients 1 year and older. It is also used off-label for avian influenza strains like H5N1 and H7N9.
Oseltamivir works by inhibiting the neuraminidase enzyme on the surface of influenza viruses. This enzyme is responsible for releasing newly formed viral particles from infected cells. By blocking neuraminidase, oseltamivir prevents the virus from spreading to new cells in your body, reducing the severity and duration of flu symptoms — typically shortening illness by about one to two days when started early.
The standard adult treatment dose is 75 mg twice daily for 5 days. Pediatric dosing is weight-based. A dose reduction is required for patients with reduced kidney function (CrCl 30–60 mL/min).
Oseltamivir currently has a findability score of 55 out of 100, reflecting intermittent supply challenges. The ASHP has listed an active shortage as of January 2026, with multiple generic manufacturers reporting back orders due to the severe 2025–2026 flu season. Some capsule strengths and the oral suspension are particularly affected. You may need to call several pharmacies or ask your pharmacist about alternative strengths or forms.
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Oseltamivir is commonly prescribed by a wide range of healthcare providers, including:
It is also widely available through telehealth platforms, making it convenient to get a prescription without an in-person visit during flu season.
No, oseltamivir is not a controlled substance. It has no DEA scheduling and does not carry any risk of abuse or dependence. It can be prescribed and dispensed without the additional restrictions that apply to controlled medications.
Taking oseltamivir with food can help reduce nausea. In rare cases, serious side effects may occur, including neuropsychiatric events (abnormal behavior, delirium, hallucinations) — primarily reported in pediatric patients — severe allergic reactions, and elevated liver enzymes.
There are no major food interactions. Oseltamivir can be taken with or without food.
Oseltamivir remains one of the most widely prescribed antiviral medications for influenza and is a critical tool during flu season. While the 2025–2026 flu season has created supply challenges, generic versions are available from multiple manufacturers and prices are reasonable with coupon cards. If your pharmacy is out of stock, try using Medfinder to locate availability nearby, ask about the oral suspension as an alternative, or consider asking your doctor about Xofluza as a single-dose alternative.
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