How to Save Money on Xofluza 80 Mg Dose Pack in 2026: Coupons, Discounts, and Patient Assistance

Updated:

February 14, 2026

Author:

Peter Daggett

Summarize this blog with AI:

Xofluza 80 Mg Dose Pack can cost over $200 without insurance. Learn how to save with coupons, discount cards, and patient assistance programs in 2026.

Xofluza Works Great — But the Price Can Be a Shock

Xofluza 80 Mg Dose Pack (Baloxavir Marboxil) is one of the most convenient flu treatments available. One dose, and you're done. But if you've seen the price tag without insurance — $200 to $280 for a single dose — you might be wondering if there's a more affordable way to get it.

The good news is that there are several ways to significantly reduce what you pay for Xofluza. In some cases, you can bring the cost down to as little as $35. Here's everything you need to know about saving money on Xofluza 80 Mg Dose Pack in 2026.

How Much Does Xofluza 80 Mg Dose Pack Cost Without Insurance?

Let's start with the numbers. The retail (cash) price for Xofluza 80 Mg Dose Pack varies by pharmacy, but here's what you can expect to pay without insurance:

  • Average retail price: $200 to $280 per dose pack
  • CVS: Approximately $250-$270
  • Walgreens: Approximately $240-$270
  • Walmart: Approximately $230-$260
  • Independent pharmacies: Varies widely, sometimes lower than chains

These prices are for the brand-name medication. There is no generic version of Xofluza available as of 2026, which is the main reason it costs so much more than other flu antivirals like generic Oseltamivir (Tamiflu), which costs $20 to $50.

Coupons and Discount Cards

The easiest way to save on Xofluza without insurance is to use a free prescription discount card or coupon. These programs negotiate lower prices with pharmacies and are free for patients to use.

GoodRx

GoodRx offers coupons that can reduce the price of Xofluza 80 Mg Dose Pack to approximately $166 at participating pharmacies. Simply search for "Xofluza" on GoodRx, select your dose and pharmacy, and show the coupon to your pharmacist.

SingleCare

SingleCare offers savings on Xofluza with prices starting around $167 for the 40 mg tablet therapy pack. Prices for the 80 mg dose pack may vary. You can download the coupon at singlecare.com and present it at the pharmacy.

Other Discount Card Options

Several other discount card programs also offer savings on Xofluza:

  • RxSaver: Compare prices across local pharmacies
  • Optum Perks: Free coupons with no membership required
  • BuzzRx: Free discount card accepted at most pharmacies
  • Inside Rx: Savings on brand-name medications

Prices vary between programs and pharmacies, so it's worth checking a few to find the best deal. These coupons cannot be combined with insurance — you use one or the other at the pharmacy counter.

Genentech's Manufacturer Savings Programs

Genentech, the maker of Xofluza, offers two major savings programs that can dramatically reduce your cost:

Xofluza Copay Card (For Commercially Insured Patients)

If you have commercial health insurance (not Medicare, Medicaid, or other government insurance), the Xofluza copay card can reduce your out-of-pocket cost to as little as $35 per prescription. The card provides up to $70 off your copay at most pharmacies.

How to get it:

  1. Visit xofluza.com/save-on-xofluza/coupon.html
  2. Download or print the copay card
  3. Present it to your pharmacist along with your insurance card and prescription

At Alto Pharmacy and Amazon Pharmacy, the manufacturer coupon is automatically applied to eligible orders — no need to present a physical card.

Direct-to-Patient Program (For Uninsured or Self-Pay Patients)

In October 2025, Genentech launched a game-changing program for patients who don't have insurance, have limited coverage, or whose plans don't cover Xofluza:

  • $50 cash pay price — that's about 70% less than the average retail price of $200+
  • Available through Alto Pharmacy, Amazon Pharmacy, and Mark Cuban Cost Plus Drug Company
  • Same-day home delivery in select U.S. markets (Alto and Amazon)
  • Nationwide mail delivery through all three pharmacies

To use this program, simply ask your doctor to send your Xofluza prescription to one of these participating pharmacies. No enrollment or application is required.

Patient Assistance Programs

If you're experiencing financial hardship, additional help may be available:

Genentech Patient Foundation

Genentech offers patient assistance for eligible uninsured and underinsured patients who cannot afford their medications. Contact the Genentech patient resource center at 1-877-GENENTECH (1-877-436-3683), Monday through Friday, 6 AM to 5 PM PT, to learn about eligibility and apply.

NeedyMeds

NeedyMeds (needymeds.org) maintains a database of patient assistance programs and can help connect you with programs specific to Xofluza and other medications.

RxAssist

RxAssist (rxassist.org) is another free resource that helps patients find assistance programs for prescription medications.

Other Ways to Save on Flu Treatment

Ask About the 40 Mg Tablets

Sometimes the 40 mg tablets may be priced differently than the 80 mg dose pack. Ask your pharmacist to compare prices. In some cases, your doctor can prescribe two 40 mg tablets (which equals the 80 mg dose) if the pricing or availability works out better.

Consider Generic Oseltamivir (Tamiflu)

If the cost of Xofluza is simply too high, even with savings programs, talk to your doctor about switching to generic Oseltamivir. A full 5-day course costs approximately $20 to $50 with a coupon card. It requires taking pills twice a day for five days instead of a single dose, but it's an effective and affordable flu treatment. Read more in our alternatives guide.

Check Your Insurance Benefits

Before assuming you need a coupon, check whether your insurance covers Xofluza. Many commercial plans do, though some may require:

  • Prior authorization: Your doctor's office submits a request to your insurance company before the prescription is approved
  • Step therapy: Your insurance may require you to try Oseltamivir first before approving Xofluza
  • Preferred pharmacy: Some plans offer better pricing at specific pharmacies

Call the number on the back of your insurance card or check your plan's formulary to find out. If your plan covers Xofluza, your copay may be much lower than the retail price — and the manufacturer copay card can reduce it even further.

Shop Around

Prices for Xofluza vary significantly between pharmacies — sometimes by $50 or more. Use Medfinder to find pharmacies with Xofluza in stock, and use GoodRx or SingleCare to compare prices across those pharmacies.

Final Thoughts

Xofluza 80 Mg Dose Pack doesn't have to cost $200 or more. With the right savings tools, you can reduce your out-of-pocket cost to as little as $35 with insurance or $50 without insurance through Genentech's programs. Free coupon cards from GoodRx and SingleCare can bring the price down to around $166 even without any special programs.

The key is knowing your options before you get to the pharmacy. Download a copay card, bookmark a coupon site, and ask your doctor about the Direct-to-Patient program — so when the flu hits, you're ready to get treated without breaking the bank.

For more tips on finding Xofluza in stock, visit our guide on how to find Xofluza 80 Mg Dose Pack near you. And for a complete overview of this medication, see what is Xofluza 80 Mg Dose Pack.

What is the cheapest way to get Xofluza 80 Mg Dose Pack?

The cheapest option is Genentech's copay card, which reduces the cost to as little as $35 for commercially insured patients. For uninsured or self-pay patients, the Direct-to-Patient program offers Xofluza for $50 through Alto Pharmacy, Amazon Pharmacy, or Cost Plus Drugs. Free coupon cards from GoodRx or SingleCare can bring the price to around $166.

Does Xofluza have a generic version that's cheaper?

No. As of 2026, there is no generic version of Xofluza (Baloxavir Marboxil). The only way to get this medication is the brand-name product from Genentech. However, savings programs can reduce the cost from $200+ to as little as $35 to $50. If cost is a major concern, generic Oseltamivir (Tamiflu) is available for $20 to $50.

Can I use a GoodRx coupon and the Genentech copay card together?

No, you cannot combine a GoodRx coupon with the Genentech copay card at the pharmacy. The Genentech copay card works with your commercial insurance to reduce your copay to as little as $35. GoodRx coupons are used instead of insurance. Choose whichever option gives you the lower price for your specific situation.

How do I sign up for Genentech's $50 Xofluza program?

No sign-up or enrollment is required. Simply ask your doctor to send your Xofluza prescription to one of the three participating pharmacies: Alto Pharmacy, Amazon Pharmacy, or Mark Cuban Cost Plus Drug Company. The $50 cash pay price is available to eligible patients who are uninsured, underinsured, or self-pay. For questions, call 1-877-GENENTECH (1-877-436-3683).

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