Medications

Eprontia

Eprontia

Previously Found with Medfinder

Comprehensive medication guide to {drug} including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.

Estimated Insurance Pricing
$10–$75 copay depending on plan; prior authorization often required since generic Topiramate tablets are preferred.
Estimated Cash Pricing
$252–$334 retail for 120 mL; as low as $85–$116 with discount coupons from GoodRx or SingleCare.
Medfinder Findability Score
55
/100
Summarize this guide with AI:

Post Author

Peter Daggett

Last Updated

February 16, 2026

Eprontia 2026 Availability, Prices, and Tips to Find

What Is Eprontia?

Eprontia is a brand-name oral liquid solution of Topiramate, manufactured by Azurity Pharmaceuticals. It is an anticonvulsant (antiepileptic) medication approved by the FDA for:

  • Initial monotherapy or adjunctive therapy for partial-onset or primary generalized tonic-clonic seizures in patients 2 years and older
  • Adjunctive therapy for seizures associated with Lennox-Gastaut syndrome in patients 2 years and older
  • Preventive treatment of migraine headaches in patients 12 years and older

Eprontia was developed specifically for patients who have difficulty swallowing tablets, including young children and those with dysphagia. It is a ready-to-use liquid that does not need to be mixed or diluted.

How Does Eprontia Work?

Eprontia contains Topiramate, which works through multiple mechanisms to reduce abnormal electrical activity in the brain:

  • Blocks voltage-gated sodium channels, reducing the rapid firing of neurons that causes seizures
  • Enhances GABA activity at GABA-A receptors, increasing the brain's natural calming signals
  • Antagonizes glutamate activity at AMPA/kainate receptors, decreasing excitatory signaling
  • Inhibits carbonic anhydrase enzymes (isozymes II and IV), which may contribute to its anticonvulsant effects

These combined actions help stabilize electrical activity in the brain, reducing seizure frequency and helping prevent migraine headaches.

What Doses Are Available for Eprontia?

Eprontia is available as a ready-to-use oral solution at a single concentration:

  • 25 mg/mL oral solution — supplied in a 120 mL bottle with a mixed-berry flavor

Your doctor will prescribe a specific dose measured in milligrams, which you measure using the provided oral syringe or dosing cup. Typical doses range from 50 mg/day up to 400 mg/day depending on your condition.

How Hard Is It to Find Eprontia in Stock?

Eprontia scores a 55 out of 100 on our findability scale, placing it in the moderate difficulty range. While there is no active FDA-reported shortage of Eprontia as of early 2026, it is a specialty liquid formulation that many retail pharmacies do not routinely stock. You may need to call several pharmacies or ask your pharmacist to place a special order. Independent and compounding pharmacies may have better luck sourcing it than large chain pharmacies.

The #1 Medication Locating Service

Find {drug} in-stock near you

Struggling to find {drug} in stock? We'll call the pharmacies, sit on hold, and find you one that can fill your prescription.

25K+
Trusted by 25,000+ Happy Patients

Who Can Prescribe Eprontia?

Eprontia can be prescribed by several types of healthcare providers:

  • Neurologists — most commonly prescribe Eprontia for epilepsy and seizure disorders
  • Epileptologists — specialists in epilepsy management
  • Pediatric neurologists — for children aged 2 and older who need a liquid formulation
  • Headache and migraine specialists — for migraine prevention in patients 12 and older
  • Primary care physicians and family medicine doctors — may prescribe for established patients
  • Psychiatrists — may prescribe off-label for bipolar disorder or other conditions

Telehealth consultations are also available for Topiramate prescriptions in many states.

Is Eprontia a Controlled Substance?

No, Eprontia is not a controlled substance. It is not scheduled by the DEA, which means it does not have the same prescribing restrictions as medications like opioids or benzodiazepines. Your doctor can prescribe it with standard refills, and you do not need a new prescription each time. However, Eprontia does require a prescription — it is not available over the counter.

Common Side Effects of Eprontia

Like all medications, Eprontia (Topiramate) can cause side effects. The most commonly reported include:

  • Numbness and tingling (paresthesia) — especially in the hands and feet
  • Loss of appetite and weight loss
  • Speech problems — difficulty finding words
  • Fatigue and drowsiness
  • Dizziness
  • Difficulty with memory and concentration
  • Changes in taste
  • Nausea and diarrhea
  • Upper respiratory tract infection

Serious but less common side effects include acute glaucoma, metabolic acidosis, kidney stones, suicidal thoughts, and decreased sweating (especially in children). Important: Eprontia carries a strong FDA warning about fetal harm — women of childbearing potential should use effective contraception while taking this medication.

Alternative Medications to Eprontia

If you are unable to find Eprontia or it is too expensive, consider these alternatives:

  • Generic Topiramate Tablets — widely available and very affordable, starting as low as $1.80 for a 30-day supply with a coupon
  • Topamax (brand Topiramate tablets) — the original brand-name tablet form
  • Trokendi XR — extended-release Topiramate capsules taken once daily
  • Qudexy XR — extended-release Topiramate capsules that can be opened and sprinkled on food
  • Generic Topiramate Oral Solution — a generic liquid form available at approximately $260 for 120 mL

Talk to your doctor before switching medications, as different formulations may have different absorption profiles.

Drug Interactions with Eprontia

Eprontia (Topiramate) can interact with several medications. Major interactions include:

  • Valproic acid (Depakote) — risk of hyperammonemia, hypothermia, and encephalopathy
  • Other carbonic anhydrase inhibitors (Zonisamide, Acetazolamide) — increased risk of metabolic acidosis and kidney stones
  • Oral contraceptives — Topiramate can reduce the effectiveness of estrogen-containing birth control
  • Phenytoin — may increase Phenytoin levels while decreasing Topiramate levels
  • Carbamazepine — may decrease Topiramate levels
  • Alcohol and CNS depressants — additive sedation; avoid or limit alcohol

Other notable interactions include Hydrochlorothiazide, Lithium, Amitriptyline, and Metformin. Always inform your doctor of all medications you are taking before starting Eprontia.

Final Thoughts on Eprontia

Eprontia fills an important niche as the first FDA-approved ready-to-use liquid formulation of Topiramate, making it a valuable option for children, elderly patients, and anyone who has difficulty swallowing tablets. While it is more expensive than generic Topiramate tablets and may not be stocked at every pharmacy, it can usually be found with some effort — earning a findability score of 55 out of 100.

If cost is a concern, ask your pharmacist about discount coupons that can bring the price down to $85–$116, or check if you qualify for Azurity Pharmaceuticals' co-pay savings or patient assistance programs. If availability is the issue, try independent pharmacies or ask your pharmacist to place a special order. Medfinder can help you locate pharmacies that have Eprontia in stock near you.

Learn more about {drug}

25,000+ have already found their meds with Medfinder.

Start your search today.
99% success rate
Fast-turnaround time
Never call another pharmacy