Amphetamine/Dextroamphetamine XR

How hard is it to find Amphetamine/Dextroamphetamine XR in stock?

Amphetamine/Dextroamphetamine XR has a findability score of 35 out of 100, meaning it is quite difficult to find in stock at most pharmacies. An ongoing nationwide shortage that began in October 2022 continues to affect supply into 2026. The 15 mg, 25 mg, and 30 mg strengths are particularly hard to find, with manufacturers reporting back orders and estimated availability in late February 2026. DEA production quotas were increased in October 2025, but high demand and supply chain disruptions have kept certain strengths intermittently unavailable.

If your pharmacy is out of stock, try using Medfinder to locate pharmacies near you that currently have your dose available. Calling independent pharmacies and asking your doctor about dose flexibility can also help.

Who Can Prescribe?

As a Schedule II controlled substance, Amphetamine/Dextroamphetamine XR requires a prescription from a licensed medical provider with DEA registration. Common prescribing specialties include:

• Psychiatrists — most commonly prescribe for ADHD in adults and children
• Primary Care/Family Medicine — frequently manage ADHD treatment
• Pediatricians — prescribe for children and adolescents with ADHD
• Neurologists — may prescribe for ADHD or narcolepsy
• Internal Medicine — can prescribe for adult ADHD patients

Telehealth providers can also prescribe Amphetamine/Dextroamphetamine XR, though some states have additional requirements for controlled substance prescriptions via telemedicine.

Is it a controlled substance?

Yes, Amphetamine/Dextroamphetamine XR is classified as a Schedule II controlled substance by the DEA. This is the highest schedule for medications with accepted medical use and reflects the drug's significant potential for abuse and physical or psychological dependence.

Because of its Schedule II classification:

• Prescriptions cannot be called in to the pharmacy in most states — they must be written or sent electronically
• No refills are allowed; a new prescription is required each month
• Pharmacies have quantity limits and may require ID at pickup
• DEA production quotas limit how much can be manufactured annually, which has contributed to the ongoing shortage

Common Side Effects

The most frequently reported side effects of Amphetamine/Dextroamphetamine XR include:

• Decreased appetite — the most common side effect, often leading to weight loss
• Insomnia — take the medication in the morning to minimize sleep disruption
• Dry mouth
• Headache
• Weight loss
• Abdominal pain
• Nervousness or anxiety
• Nausea
• Emotional lability — mood swings, irritability
• Dizziness
• Increased heart rate

Serious side effects are rare but may include sudden cardiac events in patients with structural heart abnormalities, psychiatric reactions (psychosis, mania), and peripheral vasculopathy. Contact your doctor immediately if you experience chest pain, shortness of breath, or hallucinations.

Final Thoughts

Amphetamine/Dextroamphetamine XR remains one of the most effective and widely prescribed treatments for ADHD, but the ongoing shortage that began in 2022 continues to make it challenging to find in stock. With a findability score of just 35 out of 100, patients often need to check multiple pharmacies or try different strengths.

Generic versions are affordable with discount coupons — as low as $28 per month through SingleCare — but finding a pharmacy with stock is the bigger challenge. Use Medfinder to search for pharmacies near you that currently have Amphetamine/Dextroamphetamine XR available. If your usual dose is unavailable, talk to your doctor about dose adjustments or alternative medications like Vyvanse or Concerta.