The Lisdexamfetamine Shortage Isn't Over Yet

If you've been hoping the Lisdexamfetamine shortage would be resolved by 2026, we understand the frustration. While there has been progress — the DEA has significantly increased production quotas, and more generic manufacturers are producing the medication — many patients are still struggling to fill their prescriptions as of early 2026.

Here's everything you need to know about the current state of the Lisdexamfetamine shortage, what's changed, and what you can do about it.

Is Lisdexamfetamine Still in Shortage in 2026?

Yes. As of February 2026, the ASHP (American Society of Health-System Pharmacists) continues to list Lisdexamfetamine Dimesylate capsules as being in shortage. While some manufacturers have improved their supply, others continue to report limited availability across multiple strengths.

The FDA's drug shortage database also reflects ongoing supply issues, though the situation is described as improving compared to the worst periods of 2023 and 2024.

Brand-name Vyvanse from Takeda is generally more available than generic versions, but its higher cost ($300 to $400 per month without insurance) puts it out of reach for many patients.

Why Is Lisdexamfetamine Still Hard to Find?

The shortage is driven by several overlapping factors that have persisted since late 2022:

Surging Demand

ADHD diagnoses have continued to climb, particularly among adults. The increased awareness sparked by the pandemic, combined with expanded telehealth access for mental health evaluations, has led to a sustained increase in stimulant prescriptions. Lisdexamfetamine is one of the most prescribed ADHD medications in the U.S.

DEA Production Quotas

As a Schedule II controlled substance, Lisdexamfetamine production is capped by DEA quotas. The good news: the DEA raised the aggregate production quota by approximately 24% in September 2025 and approved further increases of up to 25% for 2026. The bad news: it takes months for manufacturers to convert higher quotas into finished pills on pharmacy shelves.

Manufacturing Complexity

Over 15 generic manufacturers now produce Lisdexamfetamine, but not all have been able to maintain consistent output. Supply chain issues, quality control requirements, and raw material sourcing continue to cause intermittent disruptions.

For a deeper dive into these causes, see our post on why Lisdexamfetamine is so hard to find.

What Does Lisdexamfetamine Cost in 2026?

Cost varies significantly depending on whether you have insurance and which version you take:

• Brand Vyvanse (no insurance): $300 to $400 per month
• Generic Lisdexamfetamine (no insurance, no coupon): $200 to $360 per month
• Generic with GoodRx or similar coupon: As low as $60 to $70 per month
• With insurance: Typically $20 to $75 copay, depending on your plan and tier

Discount coupons from GoodRx, SingleCare, and Optum Perks can dramatically reduce your out-of-pocket cost for the generic version. For a complete breakdown, read our guide on how to save money on Lisdexamfetamine.

New Options and Developments for 2026

More Generic Manufacturers

The number of FDA-approved generic manufacturers has continued to grow since generics first launched in mid-2023. Companies including Teva, Sandoz, Amneal, Mylan, Hikma, Sun Pharma, Lannett, and others now produce generic Lisdexamfetamine capsules. More manufacturers means more total supply entering the market.

Chewable Tablets

Don't overlook the chewable tablet formulation. Available in 10 mg to 60 mg strengths, chewable tablets may be in stock when capsules aren't. They contain the same active ingredient and work the same way — just ask your doctor to write the prescription accordingly.

Expanded Telehealth Prescribing

Telehealth remains a viable option for getting a Lisdexamfetamine prescription. While DEA rules around telehealth prescribing of Schedule II substances have tightened, many providers can still prescribe after an initial in-person or video evaluation.

How to Find Lisdexamfetamine in Stock

Here are the most effective strategies for finding Lisdexamfetamine right now:

1. Use Medfinder to search for pharmacies with current stock in your area
2. Check independent pharmacies — they often have different supply channels than big chains
3. Ask about all strengths — your doctor may be able to combine lower strengths to match your dose
4. Try the chewable tablet form if capsules are unavailable
5. Refill early when your state allows (typically 1 to 3 days before your supply runs out)
6. Consider brand Vyvanse if generics are unavailable and cost isn't prohibitive

For more detailed strategies, read our full guide on how to find Lisdexamfetamine in stock near you.

Final Thoughts

The Lisdexamfetamine shortage is improving, but it's not over. The DEA's production quota increases are a step in the right direction, and the growing number of generic manufacturers should help stabilize supply over the coming months. In the meantime, tools like Medfinder, strategic pharmacy choices, and open communication with your doctor are your best resources.

If you're considering switching medications, check out our guide on alternatives to Lisdexamfetamine. And for information on side effects and drug interactions, we've got you covered there too.