How to Help Your Patients Save Money on Diclegis: A Provider's Guide to Savings Programs

Prescription abandonment is one of the most preventable treatment failures in obstetric care. When a patient is prescribed Diclegis for morning sickness and doesn't fill the prescription because the retail price — $286–$423 for 60 tablets — is out of reach, NVP goes untreated and can escalate. As a prescriber, you have practical tools to help patients access Diclegis at a fraction of the retail cost. This guide walks through each one.

The Core Strategy: Prescribe the Generic by Default

The most powerful cost intervention requires a single change to your prescribing workflow: always prescribe the generic — doxylamine succinate/pyridoxine hydrochloride delayed-release 10 mg/10 mg — unless there is a documented clinical reason for brand-name Diclegis.

Here's why this matters for cost:

Brand-name Diclegis (without insurance or coupon): $286–$423 for 60 tablets

Generic with GoodRx or SingleCare coupon: $45–$80 for 60 tablets

Generic with commercial insurance (Tier 1–2 formulary): $0–$30 copay per fill

The generic is FDA-approved as therapeutically equivalent. There is no clinically meaningful difference in efficacy or safety between brand and generic for the vast majority of patients.

Savings Tool 1: GoodRx and SingleCare Coupons

Train your staff to mention these coupons every time a Diclegis or doxylamine/pyridoxine prescription is sent. The script is simple: "There's a free coupon through GoodRx and SingleCare that reduces the price to $45–$80. Just search 'doxylamine pyridoxine 10mg 10mg' on the app and show it at the pharmacy."

Important caveats to communicate:

Coupons cannot be combined with insurance — patients should choose whichever is lower

Prices vary by pharmacy — comparing CVS, Walgreens, Walmart, and Costco in the app can find the best local price

The coupon applies to the generic — confirm the prescription does not specify 'brand medically necessary'

Savings Tool 2: Duchesnay USA Patient Assistance Program

Duchesnay USA, the manufacturer of brand-name Diclegis, offers a patient assistance program for uninsured and underinsured patients who meet income eligibility requirements. Your practice can initiate a referral on the patient's behalf, which is often faster than the patient navigating the application alone.

To access the program:

Contact Duchesnay USA at their medical affairs line or patient services department

Have income documentation and insurance status information available

Eligible patients may receive brand-name Diclegis at low or no cost

Savings Tool 3: Optimize Insurance Coverage

The generic doxylamine/pyridoxine is covered at Tier 1–2 on most commercial formularies, making it $0–$30 per fill for insured patients. Here's how to optimize:

Prescribe the generic, not brand — most PAs are triggered specifically by brand-name requests

If the patient needs the brand, have a PA letter ready with ICD-10 O21.0 or O21.1 and documentation of generic failure or intolerance

Recommend mail-order pharmacy for 90-day supplies — many plans offer lower per-fill costs via mail order

38,375+ patients found their medications in stock

38K+

Find Diclegis In Stock Today →

Savings Tool 4: Prescribe 90-Day Supplies

For patients who have confirmed that Diclegis is working for them, prescribing a 90-day supply via mail-order can reduce cost per tablet. Many insurance plans offer significantly lower copays for 90-day fills compared to three separate 30-day fills. Remind patients that a new prescription (not just refills) is required to switch to 90-day fills.

A Proactive Counseling Checklist for Your Team

Build this into your NVP prescription workflow:

Send prescription as generic doxylamine/pyridoxine 10 mg/10 mg (not brand-only)

Tell patient: 'Use a GoodRx or SingleCare coupon — it'll bring the price to $45–$80'

For uninsured patients: mention Duchesnay patient assistance program

If pharmacy can't find it: direct patient to medfinder.com/providers

Document that the patient was counseled on cost-reduction options in the chart

Skip the calls, skip the stress.

Find Diclegis In Stock Today →

50K+

Medications
Found

99%

Success
Rate

6+

Hours saved
on average

Final Thoughts

Cost-related non-adherence in NVP is preventable. Most patients can access generic doxylamine/pyridoxine for $45–$80 or less. The two-minute conversation investment at your next NVP visit can prevent a patient from suffering untreated morning sickness. Use medfinder for Providers to assist patients who can't find stock. For a broader clinical update on Diclegis access, see Diclegis shortage — what providers need to know.