Diclegis Shortage Update: What Patients Need to Know in 2026

If you've been trying to fill a Diclegis prescription in 2026 and your pharmacy comes back empty-handed, you may be wondering: is Diclegis in shortage? The short answer is no — not officially. But the real-world experience for many pregnant patients is that it still feels like one. Here's what you need to know.

Official Shortage Status as of 2026

As of 2026, Diclegis (doxylamine succinate/pyridoxine hydrochloride 10 mg/10 mg) is NOT listed on the FDA Drug Shortage Database, and the ASHP has no active shortage bulletin for this medication. The generic version is manufactured by multiple companies and is generally available through the national drug supply chain.

Then Why Can't Patients Find It?

The frustrating reality is that several non-shortage factors create access barriers that feel identical to a shortage:

Low pharmacy stocking: Because Diclegis is prescribed to a relatively small population (pregnant women), many pharmacies don't keep it on regular order. They stock it on demand, creating 1–3 day waits.

Brand vs. generic stocking gaps: A pharmacy may carry only the generic and not brand-name Diclegis, or vice versa. If your prescription specifies one, you may face an issue.

High cash cost: Retail price of $286–$423 per 60 tablets leads some patients to abandon their prescriptions.

Insurance prior authorization: Brand-name Diclegis may require prior authorization, causing delays of several days.

A Brief History of Diclegis Supply Disruptions

Diclegis has a complicated history in the United States. Originally marketed as Bendectin, the drug was widely prescribed for morning sickness throughout the 1960s–1970s. In 1983, the manufacturer voluntarily withdrew it — not because it was proven unsafe, but due to the financial burden of defending against lawsuits alleging birth defects, which were never substantiated in scientific evidence.

Duchesnay USA reintroduced the combination in April 2013 under the brand name Diclegis, after the FDA granted it Pregnancy Category A status. The drug has been available since then, though inconsistently stocked. Generic versions became available in the early 2020s, improving access significantly.

What About Regional Availability Issues?

Even without a national shortage, patients in rural areas or in regions with fewer pharmacy options may experience genuine difficulty finding Diclegis. Local demand patterns can temporarily deplete stock at individual pharmacies, and restocking from wholesalers can take 1–3 business days. Urban patients generally have more options and can find it more quickly.

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What Should Patients Do Right Now?

Ask specifically for the generic (doxylamine/pyridoxine 10 mg/10 mg delayed-release) — it's more widely stocked and much cheaper with a coupon.

Apply a GoodRx or SingleCare coupon to reduce the price to $45–$80 for 60 tablets before deciding the medication is unaffordable.

Check with multiple pharmacies — call 3–5 stores in your area, including independents.

Use medfinder.com to find pharmacies near you that can fill your prescription without the phone tag.

Ask your doctor about Bonjesta, ondansetron, or other alternatives if Diclegis remains unavailable in your area.

The Bottom Line

Diclegis is not in an official shortage in 2026, but real access barriers exist. The generic is your best bet for availability and affordability. For a deeper explanation of what's causing access issues, see why Diclegis is hard to find. If you need to consider another medication, see alternatives to Diclegis.