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Metadate Cd (methylphenidate hydrochloride extended-release) is a central nervous system (CNS) stimulant approved by the FDA for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in pediatric patients aged 6 to 15 years. It is also used off-label for ADHD in adults and adolescents older than 15, as well as for narcolepsy and treatment-resistant depression.
Metadate Cd uses a unique dual-bead delivery system with 30% immediate-release beads and 70% extended-release beads. This provides an initial dose of medication followed by a second release approximately 3 hours later, offering extended symptom control throughout the day with a single morning dose.
Metadate Cd works by blocking the reuptake of norepinephrine and dopamine into presynaptic neurons in the brain. This increases the concentration of these neurotransmitters in the spaces between nerve cells, which helps improve attention, focus, and impulse control in patients with ADHD.
The dual-bead capsule design releases 30% of the medication immediately upon ingestion, with the remaining 70% released approximately 3 hours later. This two-phase release mimics the effect of taking two separate doses and provides symptom coverage for much of the day without needing a second pill.
Metadate Cd is available as extended-release capsules in the following strengths:
The typical dose range is 20 mg to 60 mg taken once daily in the morning before breakfast. Capsules can be swallowed whole or opened and sprinkled onto applesauce for patients who have difficulty swallowing.
Metadate Cd has a findability score of 40 out of 100, meaning it is moderately difficult to find in stock. The ongoing stimulant medication shortage, which began in late 2022, continues to affect Metadate Cd and its generic equivalents. ASHP lists methylphenidate extended-release oral presentations as currently in shortage as of December 2025. Fewer manufacturers produce the Metadate Cd formulation specifically, making it harder to locate than some other methylphenidate products. Using Medfinder can help you locate pharmacies that currently have it in stock near you.
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As a Schedule II controlled substance, Metadate Cd can be prescribed by licensed physicians and certain other authorized prescribers. Common prescribing specialties include:
Telehealth prescribing is available for Metadate Cd in many states, though Schedule II prescribing rules and state regulations may apply.
Yes. Metadate Cd is classified as a Schedule II controlled substance by the DEA, which is the most restrictive category for medications that have an accepted medical use. Schedule II substances carry a high potential for abuse and dependence.
Because of this classification, Metadate Cd prescriptions:
The FDA-required boxed warning states that CNS stimulants, including methylphenidate, should be assessed for abuse risk before prescribing and monitored for signs of abuse during therapy.
The most frequently reported side effects of Metadate Cd include:
Serious but less common side effects include increased blood pressure and heart rate, psychiatric symptoms such as new psychosis or mania, peripheral vasculopathy (Raynaud's phenomenon), seizures, and growth suppression with long-term use in children. Contact your healthcare provider immediately if you experience chest pain, shortness of breath, or sudden changes in mood or behavior.
If you're having difficulty finding Metadate Cd, there are several alternative ADHD medications to discuss with your doctor:
Note that all stimulant medications are currently affected by supply constraints to varying degrees. Non-stimulant options like Strattera (atomoxetine) or Qelbree (viloxazine) may also be worth discussing with your prescriber.
Metadate Cd can interact with several other medications. Important drug interactions include:
Avoid alcohol while taking Metadate Cd, as it may alter the drug's release characteristics. Always inform your doctor and pharmacist of all medications you are taking.
Metadate Cd remains an effective treatment option for ADHD, but the ongoing stimulant shortage makes it challenging to find in stock. With a findability score of just 40 out of 100, patients may need to check multiple pharmacies or consider using Medfinder to locate available stock nearby.
Generic versions are significantly more affordable at $33 to $45 with a discount coupon compared to brand-name retail prices of $150 to $300. If you're having persistent difficulty finding Metadate Cd, talk to your doctor about alternative methylphenidate formulations like Concerta or Ritalin LA, which may be easier to find.
As a Schedule II controlled substance, plan ahead for refills since prescriptions cannot include refills and a new prescription is required each month. Using Medfinder's pharmacy search can save you time and frustration by showing which pharmacies near you currently have Metadate Cd in stock.
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