Comprehensive medication guide to Afirmelle 28 Day including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Estimated Insurance Pricing
$0–$25/month
Estimated Cash Pricing
$9–$50/month
Medfinder Findability Score
82/100
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Afirmelle 28 Day is a monophasic combination oral contraceptive pill used to prevent pregnancy. Each active tablet contains Levonorgestrel 0.1 mg (a progestin) and Ethinyl Estradiol 0.02 mg (an estrogen). It is the generic equivalent of Alesse, which has been discontinued in the United States. Afirmelle comes in a 28-day pack with 21 active hormone tablets and 7 inert reminder tablets to help maintain a daily pill-taking routine.
Afirmelle 28 Day is manufactured by Lupin Pharmaceuticals and is FDA-approved for the prevention of pregnancy. It is one of several generic versions of Levonorgestrel/Ethinyl Estradiol 0.1 mg/0.02 mg available on the market.
Levonorgestrel 0.1 mg / Ethinyl Estradiol 0.02 mg
28-tablet pack (21 active white tablets + 7 inert green reminder tablets). This is the only available dose and formulation for Afirmelle.
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Most side effects of Afirmelle 28 Day are mild and often improve within the first 2–3 months of use. Common side effects include:
Serious side effects are rare but require immediate medical attention. These include signs of blood clots (leg swelling, sudden chest pain, shortness of breath), stroke symptoms (sudden numbness, severe headache, vision changes), liver problems (dark urine, jaundice), and severe allergic reactions. The risk of serious side effects is higher in women who smoke, especially those over age 35.
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Aviane
One of the most widely available generics with the same formulation
Lutera
Another common generic equivalent
Aubra
/ Aubra EQ — Bioequivalent generic alternatives
Falmina
Same active ingredients and dosing
Orsythia
Another therapeutically equivalent option
Vienva
Same formulation, widely stocked
Sronyx
Bioequivalent Levonorgestrel/Ethinyl Estradiol generic
Prefer Afirmelle 28 Day? We can find it.
Antibiotics:
moderateRifampin (Rifadin) significantly reduces oral contraceptive effectiveness. Most other antibiotics do not interact, but discuss with your provider.
Anticonvulsants:
moderatePhenytoin (Dilantin), Carbamazepine (Tegretol), Phenobarbital, Topiramate (Topamax), and Oxcarbazepine (Trileptal) can decrease hormone levels.
HIV medications:
moderateCertain protease inhibitors and non-nucleoside reverse transcriptase inhibitors may interact.
Hepatitis C medications:
moderateOmbitasvir/Paritaprevir/Ritonavir (Technivie) is contraindicated with Afirmelle.
St. John's Wort:
moderateThis herbal supplement can reduce contraceptive effectiveness.
Antifungals:
moderateGriseofulvin may decrease effectiveness.
Modafinil (Provigil):
moderateMay reduce contraceptive effectiveness.
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Our medication guides are researched and written to help patients make informed decisions. All content is reviewed for accuracy and updated regularly. Learn more about our standards
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