Comprehensive medication guide to Vienva 28 Day including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Estimated Insurance Pricing
$0 copay under most ACA-compliant health insurance plans, which are required to cover FDA-approved contraceptives without cost-sharing. Some plans may designate a different LNG/EE generic as preferred; patients can accept that equivalent at $0 or request an exception.
Estimated Cash Pricing
$30–$65 retail for a 28-day pack at most chain pharmacies; as low as $15.89 with GoodRx or $10–$20 with SingleCare. A 3-month supply (84 tablets) can be found from approximately $27.92 with discount cards.
Medfinder Findability Score
75/100
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Vienva 28 Day is a combination oral contraceptive (COC) manufactured by Xiromed, LLC. It contains two synthetic hormones — levonorgestrel 0.1 mg (a progestin) and ethinyl estradiol 0.02 mg (an estrogen) — in a 28-day blister pack consisting of 21 white active tablets and 7 peach placebo tablets. It is FDA-approved for the prevention of pregnancy in females of reproductive potential.
Vienva is a monophasic pill, meaning all 21 active tablets contain the same hormone doses throughout the cycle. Its 20 mcg ethinyl estradiol dose places it in the low-dose estrogen category, which is associated with fewer estrogen-related side effects compared to higher-dose formulations. It is a generic equivalent to the discontinued brand Alesse.
When used perfectly (taken at the same time every day without missing pills), Vienva 28 Day is more than 99% effective at preventing pregnancy. With typical use, efficacy is approximately 95% per year. It does not protect against HIV, AIDS, or sexually transmitted infections.
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Vienva 28 Day prevents pregnancy through three complementary mechanisms. The primary mechanism is suppression of ovulation: the synthetic hormones suppress the brain's release of LH and FSH, which prevents the ovary from releasing an egg. Without ovulation, fertilization cannot occur.
The secondary mechanism is thickening of cervical mucus: levonorgestrel causes the mucus at the cervix to become thick and hostile to sperm, creating a physical barrier that impedes sperm movement toward the uterus.
The tertiary mechanism is alteration of the uterine lining: the hormones thin the endometrium (uterine lining), making it less receptive to implantation in the unlikely event that an egg is fertilized. The 7-day placebo phase allows a hormonal withdrawal bleed that resembles a period, while residual hormone levels maintain protection through that week.
0.1 mg levonorgestrel / 0.02 mg ethinyl estradiol — tablet (oral)
28-day blister pack: 21 white active tablets + 7 peach placebo tablets. Take one tablet daily at the same time each day.
Vienva 28 Day is not in an active FDA-declared shortage as of 2026. Xiromed continues to manufacture and distribute it. However, localized stocking gaps are common: with over 30 branded generics in the levonorgestrel/ethinyl estradiol class, pharmacies typically stock only 1-3 products based on their wholesaler contracts. Your pharmacy may carry Aviane or Lutera but not Vienva — even though all contain identical active ingredients.
The 2025 discontinuation of Sronyx (Mayne Pharma) — a bioequivalent pill with the same 0.1mg/0.02mg formulation — redirected demand to alternatives including Vienva, causing temporary stocking pressure at some pharmacies. Most of this has normalized, but gaps persist in certain locations and pharmacy networks.
If your pharmacy is out of Vienva, medfinder can contact pharmacies near you to identify which ones have it in stock, texting you the results so you don't have to spend hours on hold. You can also ask your prescriber to write for the generic name (levonorgestrel/ethinyl estradiol 0.1mg/0.02mg) with substitution permitted, allowing the pharmacist to dispense any bioequivalent including Aviane, Lutera, Falmina, Aubra EQ, or Afirmelle.
Vienva 28 Day is not a controlled substance, so no DEA registration or special prescribing authority is required beyond a standard state license with prescriptive authority. Any licensed prescriber can order it.
OB/GYN physicians — most common prescribers; routine reproductive healthcare
Primary care physicians (family medicine, internal medicine, general practice)
Nurse practitioners (NPs) — independent prescribing authority in most U.S. states
Physician assistants (PAs) — collaborative prescribing in all states
Planned Parenthood and Title X clinic providers
Telehealth is widely available for Vienva prescriptions. Platforms including Nurx, Hey Jane, Wisp, and Hers can evaluate patients online and e-prescribe Vienva or an equivalent to any in-network pharmacy. Many insurance plans also include telehealth reproductive health consultations as a preventive care benefit at no additional cost.
No. Vienva 28 Day (levonorgestrel/ethinyl estradiol) is not a controlled substance and is not classified under any DEA schedule (I–V). It is a prescription medication but has no abuse potential and no special prescription restrictions.
Because it is not controlled, Vienva can be prescribed by any licensed provider with prescribing authority, including OB/GYNs, primary care physicians, nurse practitioners, physician assistants, and telehealth providers. Prescriptions can be submitted electronically, faxed, or called in to any pharmacy. There are no refill restrictions based on controlled substance law, though individual insurance plans may limit quantity per fill.
Most side effects of Vienva 28 Day are mild and temporary, occurring most commonly during the first 1-3 months as the body adjusts:
Nausea (most common; take with food or at bedtime to reduce)
Headache
Breast tenderness or pain
Spotting or breakthrough bleeding between periods
Mood changes (including mild depression in some patients)
Decreased libido
Acne changes (improvement or flare, depending on the individual)
Blood clots (DVT): leg pain, swelling, warmth, or redness
Pulmonary embolism: shortness of breath, chest pain, coughing up blood
Stroke: sudden numbness, weakness, speech difficulty, severe headache, vision changes
Heart attack: chest pain, shortness of breath, jaw/arm pain
Liver problems: jaundice, upper right abdominal pain, dark urine, loss of appetite
Severe allergic reaction: hives, difficulty breathing, facial swelling
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Aviane 28 Day
Bioequivalent — same active ingredients (LNG 0.1mg/EE 0.02mg). One of the most widely stocked LNG/EE generics.
Aubra EQ 28 Day
Bioequivalent — same active ingredients (LNG 0.1mg/EE 0.02mg). Commonly covered at $0 under ACA plans.
Falmina 28 Day
Bioequivalent — same active ingredients (LNG 0.1mg/EE 0.02mg). Good availability at independent pharmacies.
Altavera 28 Day
Same progestin (levonorgestrel), higher dose: LNG 0.15mg/EE 0.03mg. Therapeutic switch — discuss with prescriber.
Sprintec 28 Day
Different progestin (norgestimate 0.25mg/EE 0.035mg). Widely available; also used for acne management.
Yaz 28 Day
Different progestin (drospirenone 3mg/EE 0.02mg). Also FDA-approved for PMDD and acne; similar low estrogen dose.
Prefer Vienva 28 Day? We can find it.
Ombitasvir/paritaprevir/ritonavir (Viekira Pak)
majorCONTRAINDICATED. Co-administration causes significant ALT (liver enzyme) elevation. Must stop Vienva before starting this HCV treatment.
Rifampin (Rifadin)
majorSignificantly reduces Vienva efficacy through CYP450 induction. Use backup contraception during rifampin treatment and for 28 days after stopping.
Carbamazepine (Tegretol)
majorStrong CYP450 inducer; significantly reduces levonorgestrel and ethinyl estradiol plasma levels. Consider non-hormonal or long-acting contraception.
Phenytoin (Dilantin)
majorReduces oral contraceptive hormone levels through hepatic enzyme induction. Backup contraception recommended.
Topiramate (Topamax)
moderateCan reduce contraceptive efficacy, particularly at doses over 200mg/day. Discuss with prescriber if taking for epilepsy or migraine prevention.
St. John's Wort
moderateCYP450 inducer that can reduce hormone levels and has been associated with breakthrough bleeding and contraceptive failures. Avoid while taking Vienva.
Modafinil (Provigil)
moderateMay reduce contraceptive efficacy. Use backup contraception and discuss with prescriber if taking for narcolepsy or shift work.
Grapefruit juice
minorInhibits CYP3A4; may increase ethinyl estradiol levels, potentially increasing estrogen-related side effects without affecting efficacy.
Vienva 28 Day is a well-established, low-dose combined oral contraceptive with a strong safety and efficacy record. Its 20 mcg ethinyl estradiol dose makes it a preferred choice for patients who want effective contraception with a lower estrogen burden. It is not in a national shortage, though localized availability gaps are common due to the fragmented generic oral contraceptive market.
If you have a prescription but can't find Vienva at your local pharmacy, remember that several bioequivalent alternatives contain the identical active ingredients: Aviane, Aubra EQ, Falmina, Lutera, and Afirmelle. Asking your prescriber to write for the generic name with substitution permitted gives you the most flexibility. For cost savings, ACA-compliant insurance covers oral contraceptives at $0 copay, and discount programs like GoodRx can bring the cash price down to $15-$20 per pack.
If you're having trouble locating Vienva in stock near you, medfinder contacts pharmacies near your location and texts you the results — saving you the time and frustration of calling multiple pharmacies yourself. Never go without contraceptive coverage if you can avoid it; acting early when you're running low makes all the difference.
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Our medication guides are researched and written to help patients make informed decisions. All content is reviewed for accuracy and updated regularly. Learn more about our standards
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