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Adipex-P is the brand name for Phentermine Hydrochloride, a prescription weight-loss medication approved by the FDA for short-term use (a few weeks) in adults with obesity. It is indicated for patients with a BMI of 30 or higher, or a BMI of 27 or higher with at least one weight-related condition such as hypertension, diabetes, or high cholesterol. Adipex-P is meant to be used alongside a reduced-calorie diet and exercise program. It belongs to the sympathomimetic amine class of drugs and is manufactured by Teva Pharmaceuticals.
Adipex-P works by stimulating the release of norepinephrine in the central nervous system. This triggers a "fight-or-flight" response that suppresses appetite and reduces food intake. Phentermine is chemically related to amphetamine but has a lower potential for abuse. By decreasing hunger signals, it helps patients eat less while they build healthier eating and exercise habits. The medication is typically prescribed for short-term use because its appetite-suppressing effects may diminish over time.
Adipex-P and its generic equivalent, Phentermine, are generally available at most pharmacies. Phentermine has not appeared on FDA or ASHP drug shortage lists in recent years, and supply has remained stable even during periods when other controlled substances faced shortages. However, because Adipex-P is a Schedule IV controlled substance, not every pharmacy stocks it in large quantities. You may need to call ahead to confirm availability, especially for the brand-name version. Generic Phentermine 37.5 mg tablets and capsules are widely stocked and much easier to find.
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Several types of healthcare providers can prescribe Adipex-P:
Adipex-P is also available through telehealth platforms that specialize in weight management, making it easier to get a prescription without an in-person visit.
Yes. Adipex-P (Phentermine) is classified as a Schedule IV controlled substance by the DEA. This means it has a recognized medical use but carries some potential for abuse and dependence, though lower than Schedule II or III drugs. Because of this classification, prescriptions may have restrictions such as limited refills, and some pharmacies may carry smaller quantities. Your doctor will monitor you while on this medication to watch for signs of dependence or misuse.
More serious but rare side effects include primary pulmonary hypertension, valvular heart disease, palpitations, psychosis, and seizures. Contact your doctor immediately if you experience chest pain, shortness of breath, or severe mood changes.
Adipex-P remains one of the most widely prescribed and affordable weight-loss medications in the United States. While the brand name may be harder to find at some pharmacies, generic Phentermine is widely available and can cost as little as $4 for a 30-day supply with a discount coupon. As a Schedule IV controlled substance, it requires a prescription and regular doctor monitoring, but for eligible patients it can be an effective short-term tool to jumpstart weight loss. If you're having trouble finding Adipex-P or Phentermine in stock at your local pharmacy, Medfinder can help you locate a pharmacy that has it available near you.