Adipex-P Shortage: What Providers and Prescribers Need to Know in 2026

Updated:

February 15, 2026

Author:

Peter Daggett

Summarize this blog with AI:

A provider briefing on Adipex-P (Phentermine) availability in 2026. Coverage of supply status, prescribing considerations, cost, and tools for patients.

Adipex-P Shortage: What Providers and Prescribers Need to Know in 2026

Phentermine remains one of the most frequently prescribed weight-loss medications in the United States. As patient demand for obesity pharmacotherapy continues to grow — driven in part by the success and visibility of GLP-1 receptor agonists — providers are fielding more questions about Phentermine availability, cost, and alternatives.

This briefing covers the current supply picture for Adipex-P (Phentermine Hydrochloride), prescribing implications, cost and access considerations, and practical tools to help your patients find their medication.

Current Supply Status

As of early 2026, Phentermine is not listed on the FDA Drug Shortage Database or the ASHP Drug Shortages list. Manufacturing supply from Teva Pharmaceuticals (brand Adipex-P) and multiple generic manufacturers remains stable.

However, providers should be aware that pharmacy-level availability is inconsistent. The disconnect between national supply adequacy and local stockouts is driven by factors unique to Schedule IV controlled substances, as outlined below.

Timeline: Phentermine Availability History

Phentermine has maintained a relatively stable supply history compared to other commonly prescribed controlled substances:

  • 2023: While 14 of the 20 most commonly prescribed controlled substances were in shortage, Phentermine was notably among the six that were not in shortage (Becker's Hospital Review, June 2023).
  • 2024: No ASHP or FDA shortage listings for Phentermine. The Adipex-P manufacturer savings card was discontinued (February 2024).
  • 2025-2026: Supply remains stable. No formal shortage listings. Patient complaints about availability typically reflect pharmacy stocking decisions rather than manufacturing shortfalls.

Prescribing Implications

When prescribing Phentermine in the current environment, consider the following:

Generic vs. Brand

Generic Phentermine 37.5 mg is manufactured by multiple companies and is substantially easier for pharmacies to stock and for patients to afford. Brand-name Adipex-P, while bioequivalent, is less commonly stocked and significantly more expensive (~$100-$115 vs. $4-$10 with coupons for generic).

Recommendation: Unless the patient has a documented clinical reason for brand-name Adipex-P, prescribe generic Phentermine to maximize availability and minimize cost.

Formulation Options

Multiple Phentermine formulations are available:

  • Phentermine 37.5 mg tablets/capsules (generic Adipex-P) — most commonly prescribed, once daily
  • Phentermine 8 mg tablets (Lomaira) — TID dosing, 30 minutes before meals; may be better tolerated in patients sensitive to stimulant effects
  • Phentermine ODT 15 mg and 30 mg (Suprenza) — orally disintegrating tablets for patients with swallowing difficulties

Controlled Substance Considerations

As a Schedule IV controlled substance, Phentermine prescriptions are subject to:

  • State-specific PDMP (Prescription Drug Monitoring Program) reporting
  • DEA quota limitations that affect pharmacy ordering capacity
  • Prescription validity periods that vary by state (typically 6 months)
  • Refill limitations (up to 5 refills within 6 months in most states)

Advise patients that some pharmacies may not stock Phentermine in large quantities due to these regulatory constraints.

Availability Picture: Why Patients Report Difficulty

Despite stable manufacturing supply, your patients may report difficulty finding Phentermine for several reasons:

  1. DEA ordering quotas: Pharmacies have limits on how much they can order, and some proactively limit Schedule IV inventory.
  2. Chain pharmacy policies: Some large chains have tightened controlled substance stocking in response to regulatory scrutiny, affecting stimulant-class medications broadly.
  3. Demand increases: The overall increase in obesity pharmacotherapy prescribing has raised demand at the pharmacy level.
  4. Regional variation: Availability can vary significantly by geography, with urban areas generally having better stock than rural regions.

Cost and Access in 2026

Here is the current pricing landscape for Phentermine:

  • Generic Phentermine 37.5 mg (30 tablets): $4-$10 with discount coupons (GoodRx, SingleCare); $15-$30 cash price without coupons
  • Brand Adipex-P 37.5 mg (30 tablets): $100-$115 retail
  • Insurance: Most commercial plans and Medicare Part D cover generic Phentermine at Tier 1 or Tier 2 ($5-$25 copay). Some plans require prior authorization or documentation of BMI criteria.
  • Manufacturer programs: The Adipex-P savings card was discontinued in February 2024. The Teva Cares Foundation Patient Assistance Program may provide medication at no cost to eligible uninsured/underinsured patients (tevacares.org).

Tools and Resources for Your Practice

Several tools can help you and your patients navigate availability challenges:

Medfinder for Providers

Medfinder offers real-time pharmacy stock information that you can share with patients or integrate into your workflow. When a patient reports they can't find Phentermine, direct them to Medfinder to locate a pharmacy with current stock.

Patient Education Resources

Consider sharing these guides with patients who are struggling to fill their prescriptions:

Alternative Prescribing Options

When Phentermine is consistently unavailable for a patient, consider:

  • Qsymia (Phentermine/Topiramate ER) — FDA-approved for long-term use; requires REMS certification
  • Contrave (Naltrexone/Bupropion ER) — non-controlled; good option for patients with concurrent mood disorders or food cravings
  • Wegovy (Semaglutide 2.4 mg) — GLP-1 RA with strong efficacy data; weekly injection
  • Zepbound (Tirzepatide) — dual GIP/GLP-1 RA; newest option with robust weight-loss outcomes

Looking Ahead

The landscape for obesity pharmacotherapy is evolving rapidly. Phentermine remains a reliable, affordable first-line option, but the growing pipeline of GLP-1 and dual-agonist medications is shifting prescribing patterns. Key developments to watch:

  • Expanded insurance coverage for newer weight-loss medications
  • Potential reclassification discussions for anti-obesity medications
  • Ongoing DEA controlled substance quota adjustments that may affect pharmacy-level supply
  • New oral GLP-1 formulations in development that could further shift demand away from traditional appetite suppressants

Final Thoughts

Phentermine supply is stable at the manufacturing level, but pharmacy-level availability remains inconsistent due to controlled substance regulations and surging demand. Prescribing generic Phentermine, educating patients about tools like Medfinder, and maintaining familiarity with alternative agents will help ensure your patients can access effective weight management pharmacotherapy in 2026.

Is Phentermine currently in a drug shortage?

No. As of early 2026, Phentermine is not listed on FDA or ASHP drug shortage databases. Manufacturing supply is stable. Patient-reported difficulty finding the medication typically reflects pharmacy-level stocking decisions and DEA controlled substance ordering constraints rather than a supply shortage.

Should I prescribe brand Adipex-P or generic Phentermine?

Generic Phentermine is recommended for most patients. It is bioequivalent to Adipex-P, more widely stocked by pharmacies, and dramatically less expensive ($4-$10 vs. $100-$115 for brand). The Adipex-P manufacturer savings card was discontinued in February 2024, further reducing the value proposition of brand-name prescribing.

What alternatives can I prescribe if a patient can't find Phentermine?

Options include Lomaira (Phentermine 8 mg TID), Qsymia (Phentermine/Topiramate ER — requires REMS), Contrave (Naltrexone/Bupropion — non-controlled), Wegovy (Semaglutide 2.4 mg weekly injection), and Zepbound (Tirzepatide). Choice depends on patient comorbidities, insurance coverage, and cost considerations.

How can I help patients find Phentermine in stock?

Direct patients to Medfinder (medfinder.com/providers) for real-time pharmacy stock information. Recommend they try independent pharmacies, ask their pharmacist to special-order the medication, and consider generic Phentermine if they've been seeking brand Adipex-P specifically.

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