What Is Konvomep? Uses, Dosage, and What You Need to Know in 2026

Konvomep is an FDA-approved prescription liquid medication that combines two well-established drugs—omeprazole and sodium bicarbonate—into a single oral suspension. It's designed for patients who need a PPI but cannot take standard capsules or tablets. Here's a comprehensive overview of what Konvomep is, how it's used, and what you should know before taking it.

What Is Konvomep?

Konvomep is the brand name for omeprazole and sodium bicarbonate for oral suspension, manufactured by Azurity Pharmaceuticals. It was FDA-approved on August 30, 2022, and became commercially available in early 2023. Konvomep is dispensed as a kit containing two bottles: one with omeprazole powder and one with a strawberry-flavored sodium bicarbonate diluent. A pharmacist reconstitutes these into a liquid suspension before dispensing.

After reconstitution, each mL of Konvomep contains 2 mg omeprazole and 84 mg sodium bicarbonate. The standard adult dose is 40 mg of omeprazole (= 20 mL of suspension) once daily.

What Is Konvomep Used For?

Konvomep has two FDA-approved indications in adults:

Active benign gastric ulcer: Konvomep is approved for short-term treatment (4–8 weeks) of active stomach ulcers (gastric ulcers). The standard dose is 40 mg once daily for 4 to 8 weeks.

Reduction of risk of upper GI bleeding in critically ill patients: Konvomep is used in hospital/ICU settings to reduce the risk of stress-related upper gastrointestinal bleeding. The dosing regimen starts with 40 mg, then 40 mg 6–8 hours later, followed by 40 mg once daily for 14 days.

In addition to these FDA-approved uses, doctors sometimes prescribe Konvomep off-label for conditions that omeprazole generally treats—such as GERD, erosive esophagitis, and heartburn—in patients who require a liquid formulation.

Who Is Konvomep For?

Konvomep is approved for adults only (18 years and older). It is specifically valuable for:

Patients with dysphagia (difficulty swallowing) who cannot swallow capsules or tablets

Patients receiving nutrition or medications through a nasogastric (NG) or orogastric (OG) tube

ICU patients requiring stress ulcer prophylaxis and GI bleeding prevention

Patients transitioning from IV acid suppression who need an oral liquid bridge therapy

How to Take Konvomep

Follow your doctor's and pharmacist's instructions carefully. Key administration points:

Take on an empty stomach, at least 1 hour before a meal. If taken with or after food, the omeprazole AUC is reduced by approximately 22–27%.

Shake the bottle well before each use to ensure the suspension is evenly mixed.

Measure with the provided measuring device, not a kitchen spoon. The standard 40 mg dose = 20 mL.

Store refrigerated at 36–46°F (2–8°C). Discard unused reconstituted suspension after 30 days. Do not freeze.

For tube feeding patients: Suspend enteral feedings approximately 3 hours before and 1 hour after administration.

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Konvomep Dosage Guide

Active gastric ulcer: 40 mg once daily for 4 to 8 weeks

GI bleeding prevention (critically ill): 40 mg loading dose, then 40 mg 6–8 hours later, then 40 mg once daily for 14 days

All doses are based on the omeprazole component. At 2 mg/mL, a 40 mg dose equals 20 mL of reconstituted suspension.

Is Konvomep Available as a Generic?

No. As of 2026, there is no FDA-approved generic equivalent to Konvomep. It remains a brand-only product from Azurity Pharmaceuticals. The closest related product is Zegerid, an older brand of omeprazole/sodium bicarbonate available as capsules and powder packets—but not as a reconstituted liquid suspension kit.

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Where to Find Konvomep

Konvomep isn't stocked at every pharmacy due to its refrigeration requirements and specialty status. If your usual pharmacy doesn't carry it, medfinder can call pharmacies in your area to find which ones have it in stock. medfinder is a paid service that handles the pharmacy calling for you and texts you the results.

Want to understand how Konvomep works at a deeper level? Read our guide on Konvomep's mechanism of action.