Updated: January 25, 2026
What Is Jasmiel 28 Day? Uses, Dosage, and What You Need to Know in 2026
Author
Peter Daggett

Summarize with AI
Everything you need to know about Jasmiel 28 Day: what it is, what it treats, how to take it, who should avoid it, and how it compares to Yaz and other birth control options.
Jasmiel 28 Day is a prescription combination oral contraceptive pill that contains two hormones: drospirenone (a progestin) and ethinyl estradiol (an estrogen). It's an AB-rated generic equivalent of Yaz, manufactured by Afaxys Pharma, LLC. This means it contains the same active ingredients in the same amounts and has been certified by the FDA to be therapeutically equivalent to the brand-name drug.
This guide answers the most common questions patients have about Jasmiel 28 Day, from what it's used for to how to take it correctly.
What Is Jasmiel 28 Day Used For?
Jasmiel 28 Day is FDA-approved for three indications:
- Contraception: Prevention of pregnancy in females of reproductive potential. When taken correctly and consistently, combination oral contraceptives have a typical-use failure rate of about 7% per year and a perfect-use failure rate of about 0.3%.
- PMDD (Premenstrual Dysphoric Disorder): Treatment of PMDD symptoms — including markedly depressed mood, anxiety or tension, and emotional instability — in women who choose to use an oral contraceptive for birth control. Note: the effectiveness for PMDD beyond three menstrual cycles has not been fully evaluated.
- Moderate acne: Treatment of moderate acne in females at least 14 years old who also want contraception. The antiandrogenic properties of drospirenone contribute to its effectiveness for acne.
What Does Jasmiel 28 Day Contain?
Each 28-day blister pack of Jasmiel contains:
- 24 active light pink tablets: Each containing 3 mg drospirenone (DRSP) and 0.02 mg ethinyl estradiol (EE), debossed with "S" on one side and "77" on the other
- 4 green inert (placebo) tablets: Taken on days 25-28; contain no active hormones, debossed with "S" on one side and "37" on the other
Inactive ingredients in the active tablets include corn starch, FD&C Red No. 40, lactose monohydrate, magnesium stearate, povidone, talc, and Vitamin E.
How Do You Take Jasmiel 28 Day?
Take one tablet by mouth at the same time every day, in the order shown on the blister pack. Jasmiel should be taken preferably after the evening meal or at bedtime, with some liquid as needed — this can reduce nausea.
- Days 1-24: Take one active pink tablet daily
- Days 25-28: Take one green placebo tablet daily
- Day 1 of next pack: Start the new pack the day after the last green tablet, regardless of whether your period has occurred
When starting for the first time, begin on Day 1 of your period (Day 1 Start) or on the first Sunday after your period begins (Sunday Start). Use backup contraception (such as condoms) for the first 7 days if using Sunday Start.
Who Should NOT Take Jasmiel 28 Day?
Jasmiel 28 Day is contraindicated in patients with:
- Renal impairment or adrenal gland disorder
- Uncontrolled high blood pressure, heart disease, or history of stroke, heart attack, or blood clots
- Liver disease or liver cancer
- Undiagnosed vaginal bleeding
- Age over 35 AND a smoker
- Breast, uterine, cervical, or vaginal cancer (hormone-sensitive cancers)
- Severe migraines with aura
- Taking HCV combination therapy (ombitasvir/paritaprevir/ritonavir ± dasabuvir)
How Is Jasmiel Different from Other Birth Control Pills?
Jasmiel's progestin — drospirenone — is a synthetic progestogen derived from spironolactone. Unlike most other progestins, drospirenone has:
- Anti-mineralocorticoid activity: A mild diuretic-like effect that may reduce bloating and water retention compared to other progestins
- Antiandrogenic activity: Blocks androgen receptors, contributing to its effectiveness for acne and potentially reducing acne-related oil production
Additionally, Jasmiel uses a 24/4 schedule (24 active days, 4 placebo days) rather than the traditional 21/7 schedule. This shorter pill-free interval maintains tighter hormonal control and may reduce hormone-withdrawal symptoms.
Getting Jasmiel 28 Day: Finding It and Affording It
The retail cash price for Jasmiel 28 Day runs from $103 to $148 per pack without insurance, but with GoodRx it drops to around $32/pack, and with SingleCare the generic can be as low as $6.20. Most patients with ACA-compliant insurance pay $0 copay. If your pharmacy doesn't have it in stock, medfinder can call nearby pharmacies to find which ones have it. For a full breakdown of savings options, see our guide on how to save money on Jasmiel 28 Day in 2026.
Frequently Asked Questions
Jasmiel 28 Day is FDA-approved for three uses: (1) preventing pregnancy as a contraceptive, (2) treating symptoms of premenstrual dysphoric disorder (PMDD) in women who also choose it for birth control, and (3) treating moderate acne in females 14 years and older who want oral contraceptive coverage.
Yes. Jasmiel 28 Day is an AB-rated FDA-approved generic equivalent of Yaz (brand name by Bayer). Both contain drospirenone 3 mg and ethinyl estradiol 0.02 mg in a 24-active / 4-placebo tablet regimen. They are therapeutically equivalent — same efficacy, same safety profile, same indications.
Take one tablet daily at the same time each day, in the order shown on the blister pack. Days 1-24: take active pink tablets. Days 25-28: take green placebo tablets. Start a new pack the day after the last green tablet. Take at bedtime or with food to reduce nausea. Never skip active tablets without talking to your doctor.
Yes. Jasmiel 28 Day is FDA-approved for treatment of moderate acne in females at least 14 years old who choose an oral contraceptive for birth control. The progestin drospirenone has antiandrogenic properties that help reduce acne by blocking androgens that contribute to excess oil production.
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