Alternatives to Mydayis if you can’t fill your prescription

Nick Demarcus

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June 3, 2025

We know that finding pharmacies with Mydayis in stock is a challenge millions of Americans struggle with every month, but fortunately, there are lots of alternative medications available for individuals with ADHD. Always be sure to consult your doctor to evaluate a medication change. With the disclaimer out of the way, let's dive into Mydayis! 

Pro tip - If you can’t find Mydayis in stock near you, you can use Medfinder’s online medication locator tool to find a pharmacy with your medications in stock!

What is Mydayis?

Mydayis is a Schedule II Controlled Substance and part of the Central Nervous System (CNS) stimulant class of medications. It’s commonly prescribed to treat Attention Deficit Hyperactivity Disorder (ADHD) and narcolepsy.

How does Mydayis work?

Mydayis is made up of mixed amphetamine salts, and uses a special capsule with three types of beads: one releases medicine right away, and the other two release it later, so the effects last up to 16 hours. This means you can take it once in the morning and have symptom control throughout the day. It works by increasing the levels of certain natural chemicals in your brain, specifically, dopamine and norepinephrine, which help improve attention, focus, and self-control. It does this by blocking the reuptake (re-absorption) of these chemicals into nerve cells and by increasing their release, so more of them are available to help your brain function better for people with ADHD. The steady release of these chemicals throughout the day can help reduce the likelihood of spikes and crashes in symptom control, which some patients experience with shorter-acting stimulants. 

What is the difference between Mydayis and Adderall XR?

Both Mydayis and Adderall XR are prescription stimulant medications used to treat ADHD, and both contain mixed amphetamine salts as their active ingredients. However, there are important differences in their duration and formulation.

Adderall XR or “Extended Release” uses a two-phase delivery system where half the dose is released immediately, and the other half is released gradually later in the day. For many individuals with ADHD, this option is more preferable as they don't have to remember to take another dose of their medication as they go through their day. Due to this preference, Adderall XR tends to be more difficult to find in stock than Adderall IR.

Mydayis, on the other hand, uses a triple-bead release system, which delivers the medication in three phases: one immediately, and two more on a time release for a steady effect throughout the day. Mydayis can last up to 16 hours compared to Adderall XR’s 12 hours. 

Alternative medications to Mydayis

If you've tried everything and still can't manage to find Mydayis in stock, it may make sense to talk to your doctor about other options. Many medications have similar effects to Mydayis, and there are often other medication options that can get you through shortages. Some other medications that are similar to Mydayis are:

  • Adderall XR (amphetamine mixed salts) 
    • Adderall XR is a similar stimulant to Mydayis in how it works that contains a mix of immediate-release and delayed-release amphetamine salts. This formulation is designed to provide two separate doses over time, helping to extend the medication’s effects throughout the day and it may not last as long as some individuals need. 
  • Concerta or Ritalin (methylphenidate)
    • Methylphenidate (commonly known as Ritalin or Concerta) is a different type of stimulant than Adderall or Mydayis, though it still impacts the neurotransmitters Norepinephrine and dopamine in the brain. Methylphenidate is designed to solely block the reuptake of dopamine and norepinephrine in the brain, while Adderall increases the release of dopamine and norepinephrine and inhibits their reuptake. 
  • Focalin (Dexmethylphenidate)
    • Dexmethylphenidate is quite similar to Methylphenidate, but is considered more potent than Methylphenidate on a milligram-to-milligram basis. Generally, it is prescribed at roughly half the dosage of Methylphenidate. Both are available in immediate and extended release formulations, but some studies show that Dexmethylphenidate may last a bit longer. 

Always consult with your healthcare provider before making any changes to your medication routine.

Final Thoughts

We know how challenging it can be when a regular medication you are taking suddenly is nowhere to be found. Thankfully, there are a number of alternative medications to Mydayis, like:

  1. Adderall (amphetamine mixed salts) 
  2. Concerta or Ritalin (methylphenidate)
  3. Focalin (Dexmethylphenidate)

If you don’t want to change your medication, be sure to check out our guide on how to find Mydayis in stock for tips and tricks on how to find a pharmacy that can fill your prescription.

How do I find a pharmacy that has Mydayis in stock near me?

You can try a medication finding tool, like Medfinder, and have the service find Mydayis nearby for you. You can try calling local pharmacies during off-peak hours, like Saturdays. Finally, focusing on independent pharmacies instead of chains may help you find your medication faster.

How to find Mydayis without calling every pharmacy?

A medication finding tool, like Medfinder, is the best way to find Mydayis quickly without having to call every pharmacy around. Otherwise, you are going to need to contact each pharmacy in your local area.

Can I use Medfinder to find Mydayis near me?

Absolutely! Medfinder can find Mydayis and other stimulant medications at a nearby pharmacy for you.

What should I do if no pharmacy has Mydayis?

You can always talk to your doctor about alternative medication options, which may be in stock at a local pharmacy. If you have not tried Medfinder, you may still be able to find Mydayis in stock without having to switch Medications.

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