Comprehensive medication guide to Lexette including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Estimated Insurance Pricing
$0–$50/month
Estimated Cash Pricing
$25–$1,000/month
Medfinder Findability Score
55/100
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Lexette is a brand-name prescription topical foam containing Halobetasol Propionate 0.05%, a super high potency (Class I) topical corticosteroid manufactured by Mayne Pharma. It is FDA-approved for the treatment of plaque psoriasis in patients 12 years of age and older. Lexette works by reducing inflammation, redness, itching, and scaling on the skin. It is applied as a thin layer to affected areas twice daily for up to 2 weeks, with a maximum of 50 grams per week.
Lexette Foam 0.05%
50g can
Lexette Foam 0.05%
100g (supplied as two 50g cans)
![How to Find a Doctor Who Can Prescribe Lexette Near You [2026 Guide]](/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2Fvur4atr4%2Fproduction%2Fed24daaaa5dd62fc1497a5ac35c55250ca8c6e6f-1024x1024.png%3Frect%3D0%2C256%2C1024%2C512%26w%3D400%26h%3D200%26auto%3Dformat&w=828&q=75)
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Cream 0.05% (generic, also branded as Ultravate) — cream
Ointment 0.05% (generic, also branded as Ultravate) — ointment
Lotion 0.01% (branded as Bryhali)
More serious but less common side effects include HPA axis suppression (seen in 24–26% of clinical study participants), skin atrophy, stretch marks, and secondary skin infections. Do not use for longer than 2 weeks or apply more than 50 grams per week. Contact your doctor if you experience worsening symptoms or signs of skin thinning.
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Clobetasol Propionate
Another super-potent (Class I) topical corticosteroid available as cream, ointment, foam, shampoo, and solution. Generics are widely available at lower cost.
Bryhali (Halobetasol Propionate 0.01% Lotion)
A lower concentration halobetasol lotion approved for up to 8 weeks of daily use, offering a longer treatment duration.
Betamethasone Dipropionate
A high potency topical corticosteroid available as cream, ointment, and lotion. Slightly less potent but widely available and affordable as a generic.
Calcipotriene/Betamethasone (Enstilar, Taclonex)
A combination product pairing a vitamin D analog with a corticosteroid to both reduce inflammation and slow skin cell growth. Available as foam and ointment.
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Other topical corticosteroids
moderateUsing multiple topical steroids simultaneously can increase the risk of systemic absorption and HPA axis suppression.
Oral corticosteroids (e.g., Prednisone)
moderateConcurrent use may compound the risk of adrenal suppression and other systemic steroid side effects.
Other immunosuppressive topical agents
moderateMay increase the risk of local skin reactions and systemic immunosuppression.
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