Comprehensive medication guide to {drug} including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Gonal F (Follitropin Alfa) is a recombinant human follicle-stimulating hormone (r-hFSH) manufactured by EMD Serono. It is a fertility medication used to stimulate the growth and maturation of ovarian follicles in women undergoing fertility treatment, including ovulation induction and assisted reproductive technology (ART) cycles such as IVF. Gonal F is also approved to induce spermatogenesis in men with hypogonadotropic hypogonadism.
Gonal F is administered as a subcutaneous injection, most commonly using the Redi-ject prefilled pen for convenient self-injection at home.
Gonal F works by mimicking the body's natural follicle-stimulating hormone (FSH). It binds to FSH receptors on granulosa cells in the ovary, promoting the growth and development of ovarian follicles and stimulating estradiol production. In women undergoing fertility treatment, this controlled ovarian stimulation allows the development of one or more mature eggs for ovulation induction or egg retrieval during IVF.
In men with hypogonadotropic hypogonadism, Gonal F stimulates the Sertoli cells in the testes to support spermatogenesis (sperm production), typically in combination with human chorionic gonadotropin (hCG).
Your fertility specialist will determine the appropriate dose based on your treatment protocol, ovarian response, and blood estradiol levels.
Gonal F can be moderately difficult to find, particularly certain pen strengths like the 900 IU Redi-ject. As a biologic medication with specialized manufacturing, Gonal F has experienced periodic supply constraints. Specialty fertility pharmacies tend to have more reliable stock than general retail pharmacies. If your local pharmacy is out of stock, Medfinder can help you locate Gonal F at pharmacies near you.
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Gonal F should only be prescribed by physicians experienced in infertility treatment who have access to appropriate monitoring facilities. The most common prescribers include:
No, Gonal F is not a controlled substance. It does not have a DEA schedule and does not carry the same prescribing restrictions as controlled medications. However, because Gonal F is a potent biologic that requires careful medical monitoring (ultrasound and bloodwork) during treatment, it is only available by prescription and should be used under the close supervision of a fertility specialist.
Serious side effects include Ovarian Hyperstimulation Syndrome (OHSS), which can be life-threatening, multiple pregnancies, blood clots, and ovarian torsion. Contact your doctor immediately if you experience severe abdominal pain, rapid weight gain, difficulty breathing, or decreased urination.
Gonal F does not have major pharmacokinetic drug-drug interactions. However, it is frequently used as part of complex fertility protocols that include other hormonal medications, and dosing must be carefully coordinated:
Always inform your fertility team of all medications, supplements, and herbal products you are taking.
Gonal F is a critical fertility medication for thousands of patients pursuing IVF, IUI, and other assisted reproductive treatments each year. While it is generally available through specialty fertility pharmacies, certain pen strengths can experience intermittent supply constraints due to its complex biologic manufacturing process. The high cost — often $1,800 to $6,000+ per IVF cycle — makes it essential to explore all coverage options, including insurance fertility benefits, EMD Serono's Compassionate Care Program, and specialty pharmacy pricing.
If you're having trouble finding Gonal F in stock at your pharmacy, Medfinder can help you search pharmacies near you that currently have it available. Don't let a supply issue delay your treatment cycle.
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