Comprehensive medication guide to Enpresse 28 Day including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Estimated Insurance Pricing
Most insurance plans cover Enpresse 28 Day generics with $0 copay under the ACA contraceptive mandate.
Estimated Cash Pricing
Enpresse 28 Day typically costs $29 to $75 per pack without insurance, or as low as $11 to $30 with a discount card.
Medfinder Findability Score
65/100
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Enpresse 28 Day is a triphasic combination oral contraceptive containing levonorgestrel (a progestin) and ethinyl estradiol (an estrogen). It is FDA-approved for the prevention of pregnancy. The triphasic design means the hormone levels change across three phases during each 28-day cycle, more closely mimicking the body's natural hormonal fluctuations.
In addition to contraception, Enpresse 28 Day is sometimes prescribed off-label for regulating menstrual cycles, reducing menstrual cramps, managing endometriosis symptoms, treating acne, and controlling abnormal uterine bleeding.
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Enpresse 28 Day works through three primary mechanisms to prevent pregnancy:
Phase 1 (6 pink tablets)
0.050 mg levonorgestrel / 0.030 mg ethinyl estradiol
Phase 2 (5 white tablets)
0.075 mg levonorgestrel / 0.040 mg ethinyl estradiol
Phase 3 (10 orange tablets)
0.125 mg levonorgestrel / 0.030 mg ethinyl estradiol
7 light-green inert (placebo) tablets
Enpresse 28 Day has a findability score of 65 out of 100, meaning it can be intermittently difficult to locate. The Enpresse brand name has been largely discontinued by Teva Pharmaceuticals after closing its Irvine, California manufacturing plant in 2022. However, generic triphasic levonorgestrel/ethinyl estradiol tablets remain available from multiple manufacturers. If your pharmacy doesn't have Enpresse specifically, ask about generic equivalents like Trivora-28 or other triphasic levonorgestrel/ethinyl estradiol products. Use Medfinder to check real-time availability near you.
Enpresse 28 Day can be prescribed by a wide range of healthcare providers, including:
Telehealth services also prescribe Enpresse 28 Day and its generic equivalents, making it convenient to get a prescription without an in-person visit.
No, Enpresse 28 Day is not a controlled substance. It has no DEA scheduling and does not carry any restrictions related to controlled substance regulations. It requires a prescription but can be obtained at any pharmacy without special dispensing requirements.
Like all combination oral contraceptives, Enpresse 28 Day may cause side effects. Common side effects include:
Serious side effects are rare but include blood clots, stroke, heart attack, liver tumors, and gallbladder disease. Seek immediate medical attention if you experience sudden severe headache, chest pain, leg swelling, or vision changes.
Boxed Warning: Cigarette smoking increases the risk of serious cardiovascular side effects, especially in women over 35 who smoke 15 or more cigarettes per day.
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Trivora-28:
Same triphasic levonorgestrel/ethinyl estradiol formulation from a different manufacturer
Levlen 28:
Monophasic levonorgestrel/ethinyl estradiol combination oral contraceptive
Tri-Sprintec:
Triphasic oral contraceptive with norgestimate/ethinyl estradiol
Ortho Tri-Cyclen:
Triphasic oral contraceptive with norgestimate/ethinyl estradiol, also FDA-approved for acne
Prefer Enpresse 28 Day? We can find it.
Rifampin:
moderateSignificantly reduces contraceptive effectiveness
Anticonvulsants:
moderatePhenytoin, carbamazepine, phenobarbital, topiramate, felbamate, oxcarbazepine
HIV medications:
moderateRitonavir, nelfinavir, efavirenz
St. John's Wort:
moderateHerbal supplement that reduces contraceptive effectiveness
Bosentan:
moderateUsed for pulmonary arterial hypertension
Lamotrigine:
moderateOral contraceptives may reduce lamotrigine levels, affecting seizure control
Certain antibiotics:
moderateAmpicillin, tetracycline (use backup contraception as a precaution)
Enpresse 28 Day is an effective triphasic oral contraceptive, but the brand name has been largely discontinued. Generic equivalents containing the same triphasic levonorgestrel/ethinyl estradiol formulation are widely available and typically covered at no cost under insurance. If you're having trouble finding Enpresse 28 Day specifically, ask your pharmacist about Trivora-28 or other generic triphasic levonorgestrel/ethinyl estradiol products. Use Medfinder to check real-time stock at pharmacies near you and save time.
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Our medication guides are researched and written to help patients make informed decisions. All content is reviewed for accuracy and updated regularly. Learn more about our standards
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