Comprehensive medication guide to Darifenacin XR including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Estimated Insurance Pricing
$10–$50/month
Estimated Cash Pricing
$20–$350/month
Medfinder Findability Score
65/100
Summarize with AI
On this page
Darifenacin XR (brand name Enablex) is a prescription medication used to treat overactive bladder (OAB). It helps reduce symptoms of urge urinary incontinence, urgency, and urinary frequency. Darifenacin belongs to a class of drugs called antimuscarinics (also known as anticholinergics). It is available as an extended-release tablet in 7.5 mg and 15 mg strengths, taken once daily. The brand-name version, Enablex, was originally manufactured by Novartis but has been largely replaced by more affordable generic versions produced by Par Pharmaceutical, Patriot Pharmaceuticals, and others.
7.5 mg extended-release tablet (starting dose) — tablet
15 mg extended-release tablet (may be increased after at least 2 weeks) — tablet
![Why Is Darifenacin XR So Hard to Find? [Explained for 2026]](/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2Fvur4atr4%2Fproduction%2Fc16c76d036a17812608303712d484bdc08cee24e-1024x1024.png%3Frect%3D0%2C256%2C1024%2C512%26w%3D400%26h%3D200%26auto%3Dformat&w=828&q=75)
![How to Find a Doctor Who Can Prescribe Darifenacin XR Near You [2026 Guide]](/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2Fvur4atr4%2Fproduction%2F0e9e53cdf3ba7ec98d03d02c994e7a561db0c207-1024x1024.png%3Frect%3D0%2C256%2C1024%2C512%26w%3D400%26h%3D200%26auto%3Dformat&w=828&q=75)
![Why Is Darifenacin XR So Hard to Find? [Explained for 2026]](/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2Fvur4atr4%2Fproduction%2Fd0d11f7c09da245bfb6c2ad4dc6f3bdbafec6885-1024x1024.png%3Frect%3D0%2C256%2C1024%2C512%26w%3D400%26h%3D200%26auto%3Dformat&w=828&q=75)
We have a 99% success rate finding medications, even during nationwide shortages.
Need this medication?
Like all medications, Darifenacin XR can cause side effects. The most commonly reported include:
Serious but less common side effects include severe constipation or bowel obstruction, urinary retention, confusion or hallucinations, and severe allergic reactions. Contact your doctor immediately if you experience any serious side effects.
Know what you need? Skip the search.
Oxybutynin (Ditropan/Ditropan XL)
The oldest and most widely available OAB medication, available in oral, topical, and transdermal forms. May cause more anticholinergic side effects.
Solifenacin (Vesicare)
A selective muscarinic receptor antagonist available in 5 mg and 10 mg tablets with similar efficacy to Darifenacin.
Tolterodine (Detrol/Detrol LA)
One of the most commonly prescribed OAB medications, available in immediate-release and extended-release forms.
Mirabegron (Myrbetriq)
A beta-3 adrenergic agonist that works through a different mechanism. May have fewer anticholinergic side effects like dry mouth and constipation.
Prefer Darifenacin XR? We can find it.
Strong CYP3A4 inhibitors
moderate(Ketoconazole, Itraconazole, Ritonavir, Clarithromycin, Nefazodone) — Do not exceed 7.5 mg daily dose of Darifenacin when taking these drugs.
CYP2D6 substrates with a narrow therapeutic index
moderate(Flecainide, Thioridazine, tricyclic antidepressants) — Darifenacin may increase their blood levels.
Pimozide
moderateContraindicated due to risk of QT prolongation.
Other anticholinergic drugs
moderateCan cause additive anticholinergic effects (increased dry mouth, constipation, confusion).
Digoxin and Warfarin
moderateMonitor levels and INR when used together.
Grapefruit juice
moderateMay increase Darifenacin levels; use caution.
Medfinder Editorial Standards
Our medication guides are researched and written to help patients make informed decisions. All content is reviewed for accuracy and updated regularly. Learn more about our standards
ChatGPT
Claude
Perplexity
Grok
Gemini