Comprehensive medication guide to Amlodipine/Telmisartan including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Estimated Insurance Pricing
$10–$50/month
Estimated Cash Pricing
$123–$250/month
Medfinder Findability Score
55/100
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Amlodipine/Telmisartan is a combination blood pressure medication that contains two active ingredients in a single tablet. It combines an angiotensin II receptor blocker (ARB) with a calcium channel blocker (CCB) to lower blood pressure more effectively than either drug alone.
It is prescribed for hypertension (high blood pressure) — particularly when a single blood pressure medication isn't enough to reach target levels, or as initial combination therapy in patients who are likely to need more than one drug.
The brand-name version, Twynsta, has been discontinued, but generic versions remain available by prescription.
Telmisartan 40 mg / Amlodipine 5 mg
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Lower starting dose for most patients
Telmisartan 40 mg / Amlodipine 10 mg
Higher amlodipine for added blood pressure reduction
Telmisartan 80 mg / Amlodipine 5 mg
Higher telmisartan with standard amlodipine
Telmisartan 80 mg / Amlodipine 10 mg
Maximum combination dose
Serious but rare side effects include severe low blood pressure (hypotension), high potassium levels (hyperkalemia), kidney problems, and allergic reactions including angioedema (swelling of the face, lips, or throat). Contact your doctor immediately if you experience any of these.
⚠️ Black Box Warning: This medication can cause fetal harm. If you become pregnant, stop taking it and contact your doctor immediately.
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Valsartan/Amlodipine (Exforge)
Another ARB + CCB combination with widely available generics
Olmesartan/Amlodipine (Azor)
ARB + CCB combination, similar mechanism of action
Losartan + Amlodipine
Available as two separate generic tablets taken together, often the cheapest option
Amlodipine/Benazepril (Lotrel)
Combines a CCB with an ACE inhibitor instead of an ARB
Prefer Amlodipine/Telmisartan? We can find it.
Aliskiren
moderateContraindicated in patients with diabetes; increases risk of kidney problems, high potassium, and low blood pressure
Lithium
moderateTelmisartan can increase lithium levels, leading to toxicity
ACE inhibitors (e.g., Lisinopril, Enalapril)
moderateDual RAAS blockade increases risks of hypotension, hyperkalemia, and kidney impairment
NSAIDs (Ibuprofen, Naproxen)
moderateCan reduce blood pressure-lowering effect and increase kidney risk
Simvastatin
moderateAmlodipine increases simvastatin levels; maximum simvastatin dose is 20 mg/day when combined
Digoxin
moderateIncreased digoxin levels possible
Potassium supplements or potassium-sparing diuretics
moderateRisk of dangerously high potassium
Grapefruit juice
moderateMay increase amlodipine levels
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