What Is Pindolol?

Pindolol is a prescription nonselective beta-adrenergic blocker (beta blocker) used to treat high blood pressure (hypertension).

Originally sold under the brand name Visken by Novartis (Sandoz), Pindolol has been available since the 1970s. The Visken brand has been discontinued, but generic Pindolol remains available from multiple manufacturers. It is not a controlled substance.

What sets Pindolol apart from many other beta blockers is its intrinsic sympathomimetic activity (ISA) — meaning it partially stimulates beta receptors even while blocking them. This unique property may result in less resting heart rate reduction compared to beta blockers without ISA, like Propranolol or Metoprolol. Learn more about how Pindolol works.

What Is Pindolol Used For?

FDA-Approved Use

Pindolol is FDA-approved for the treatment of hypertension (high blood pressure). It can be used alone or in combination with other blood pressure medications, particularly thiazide diuretics.

Off-Label Uses

Doctors sometimes prescribe Pindolol for conditions beyond its FDA-approved indication:

• SSRI augmentation for depression — Pindolol's activity at serotonin 5-HT1A receptors has led to its use alongside SSRIs to potentially speed up or enhance antidepressant response. This is typically managed by a psychiatrist.
• Angina prophylaxis — Prevention of chest pain episodes related to coronary artery disease.
• Anxiety disorders — Like other beta blockers, Pindolol may help manage physical symptoms of anxiety such as rapid heartbeat and trembling.

How Is Pindolol Taken?

Pindolol comes in 5 mg and 10 mg oral tablets. Here's what you need to know about taking it:

• Typical starting dose: 5 mg twice daily
• Dose range: 10-60 mg per day, divided into two doses
• Dose adjustments: Your doctor will increase your dose gradually, typically every 3-4 weeks, based on your blood pressure response
• With or without food: Pindolol can be taken with or without food
• Timing: Take it at the same times each day for the best results

Critical warning: Never stop taking Pindolol suddenly. Abruptly discontinuing a beta blocker can cause rebound angina, heart attack, or dangerous irregular heartbeats. Your doctor will taper your dose gradually if you need to stop. Read more about Pindolol side effects.

Who Should Not Take Pindolol?

Pindolol is not safe for everyone. You should not take it if you have:

• Bronchial asthma or severe COPD — Pindolol blocks beta-2 receptors in the lungs and can trigger dangerous bronchospasm.
• Sinus bradycardia — An already slow heart rate can become dangerously slower.
• Heart block greater than first degree — Pindolol can worsen conduction problems in the heart.
• Cardiogenic shock — A life-threatening condition where the heart can't pump enough blood.
• Overt cardiac failure — Pindolol can worsen heart failure symptoms.

Pindolol should also be used with caution in people with:

• Diabetes — It can mask symptoms of low blood sugar.
• Thyroid disorders — It can mask symptoms of hyperthyroidism.
• Severe allergies — It may worsen anaphylactic reactions and reduce the effectiveness of Epinephrine.
• Liver or kidney problems — Dose adjustments may be needed.

Be sure to tell your doctor about all your medical conditions and medications you take before starting Pindolol.

How Much Does Pindolol Cost?

Here's what you can expect to pay for Pindolol in 2026:

• With a discount coupon: $28-$62 for 60 tablets (5 mg)
• Without a coupon (retail): $100-$225 for a 30-day supply
• With insurance: Generic Pindolol is covered by most plans, including Medicare Part D and Medicaid. It's typically a Tier 2 (preferred generic) copay — usually $5-$20 depending on your plan.

Because the brand name Visken is discontinued, there is no manufacturer savings program. However, you can save significantly with free coupon cards from GoodRx, SingleCare, and other services. See our complete guide to saving money on Pindolol.

If you're having trouble affording Pindolol, programs like NeedyMeds and RxAssist can help connect you with prescription assistance.

Finding Pindolol at a Pharmacy

Because Pindolol is an older medication with lower demand, not every pharmacy stocks it. If your local pharmacy doesn't have it:

• Use Medfinder to find pharmacies with Pindolol in stock near you
• Ask your pharmacy to order it (usually takes 1-2 business days)
• Consider a mail-order or online pharmacy
• Check our guide on how to check pharmacy stock without calling

Final Thoughts

Pindolol is an effective, well-established beta blocker for managing high blood pressure. Its unique intrinsic sympathomimetic activity makes it a distinct option among beta blockers, and its off-label use for SSRI augmentation gives it a role in psychiatry as well.

While it's not as commonly prescribed as Metoprolol or Atenolol, Pindolol remains a valuable medication for the right patient. If your doctor has prescribed it, use Medfinder to locate it quickly and check out our other Pindolol guides for alternatives, drug interactions, and side effects.