Ashlyna 91 Day Is an Extended-Cycle Birth Control Pill That Reduces Your Periods to Just 4 Per Year

Ashlyna 91 Day is a prescription combination oral contraceptive that uses a 91-day extended cycle — meaning you take active pills for 84 days straight, followed by 7 days of low-dose estrogen tablets, and you only get a period about 4 times a year. If you're tired of monthly periods or looking for a more convenient birth control option, here's everything you need to know about Ashlyna 91 Day in 2026.

What Is Ashlyna 91 Day?

Ashlyna 91 Day is the generic version of Seasonique, manufactured by Glenmark Generics. It's a combination hormonal oral contraceptive, meaning it contains two hormones:

• Levonorgestrel 0.15 mg — a synthetic progestin
• Ethinyl Estradiol 0.03 mg — a synthetic estrogen (in the 84 active tablets)

The final 7 tablets contain a low dose of Ethinyl Estradiol 0.01 mg only — no progestin. This is different from some other extended-cycle pills (like Jolessa or Quasense) that use completely inactive placebo tablets during the off week.

Ashlyna is not a controlled substance and does not require prior authorization from most insurance plans.

Other brand and generic equivalents include Seasonique, Camrese, Amethia, and Daysee.

What Is Ashlyna 91 Day Used For?

Ashlyna 91 Day is FDA-approved for one indication:

• Prevention of pregnancy in females of reproductive potential

Doctors also prescribe it off-label for several other purposes:

• Reducing menstrual frequency — The primary appeal of Ashlyna is having only 4 periods per year instead of 12.
• Managing endometriosis symptoms — Extended-cycle pills can help reduce the pain and bleeding associated with endometriosis.
• Treating heavy menstrual bleeding — Fewer cycles means less total blood loss over the year.
• Managing menstrual migraines — By reducing the number of hormone-free intervals, extended-cycle pills may help prevent menstrual migraines.
• Menstrual cycle regulation — For people with irregular periods who want a predictable schedule.

How Is Ashlyna 91 Day Taken?

Each Ashlyna 91 Day pack contains 91 tablets:

1. 84 light blue active tablets — Levonorgestrel 0.15 mg / Ethinyl Estradiol 0.03 mg. Take one daily.
2. 7 light yellow tablets — Ethinyl Estradiol 0.01 mg (low-dose estrogen only). Take one daily. Your period will occur during this phase.

Key dosing instructions:

• Take one tablet at the same time every day.
• Start on the first Sunday after your period begins.
• Take all 91 tablets consecutively — do not skip days.
• Begin your next pack immediately after finishing the current one — no breaks between packs.
• If you're starting Ashlyna for the first time, use backup contraception (like condoms) for the first 7 days.

Missed pills: If you miss one active pill, take it as soon as you remember and take the next pill at your usual time (even if that means two pills in one day). If you miss two or more pills, check the patient information insert or call your provider — you may need backup contraception.

Who Should Not Take Ashlyna 91 Day?

Ashlyna 91 Day is not safe for everyone. It's contraindicated in people with:

• Smoking habit and age over 35 — this is the most important contraindication due to serious cardiovascular risk
• Current or history of deep vein thrombosis (DVT) or pulmonary embolism
• History of stroke or heart disease
• Migraines with aura, or any migraines if over 35
• Current or history of breast cancer
• Liver tumors, severe liver disease, or acute hepatitis
• Uncontrolled high blood pressure or hypertension with vascular disease
• Diabetes with vascular complications or age over 35
• Inherited or acquired blood clotting disorders
• Undiagnosed abnormal uterine bleeding
• Use of certain Hepatitis C medications (Ombitasvir/Paritaprevir/Ritonavir)

Ashlyna should not be started until at least 4 weeks after giving birth due to increased blood clot risk. It's also not recommended while breastfeeding as it may reduce milk production.

For a complete guide to side effects, read our post on Ashlyna 91 Day side effects.

How Much Does Ashlyna 91 Day Cost?

The cost of Ashlyna 91 Day depends on whether you have insurance:

• With insurance: Most commercial insurance and Medicaid plans cover generic oral contraceptives at $0 copay under the ACA contraceptive mandate. Some plans may require a specific generic, so check with your pharmacy.
• Without insurance (cash price): The retail price ranges from $200 to $400 per 91-day pack.
• With discount cards: GoodRx, SingleCare, and other discount programs can bring the cost down to as low as $20-$35 per pack.

Medicare Part D does not typically cover contraceptives. If you need help affording Ashlyna 91 Day, check out our full savings and coupon guide.

Patients without insurance may also qualify for assistance through NeedyMeds, RxAssist, state family planning programs, or Planned Parenthood clinics that provide low-cost or free contraceptives.

Final Thoughts

Ashlyna 91 Day is an effective and convenient birth control option that lets you have just 4 periods a year. It's the generic equivalent of Seasonique, widely covered by insurance at no cost, and available at most pharmacies. The most important thing is making sure it's safe for you — especially if you smoke, have a history of blood clots, or get migraines with aura.

Talk to your doctor about whether Ashlyna 91 Day is right for you, or learn how to find a prescriber near you. If you already have a prescription, search Medfinder to find it in stock at a pharmacy nearby.