The Latest on Vijoice Availability in 2026

If you rely on Vijoice (Alpelisib) 50 mg for PIK3CA-Related Overgrowth Spectrum (PROS), you've probably wondered at some point: is this medication in shortage? The answer is more nuanced than a simple yes or no—and understanding the current landscape can help you plan ahead and avoid treatment gaps.

Here's everything patients need to know about Vijoice availability in 2026.

Is Vijoice Still in Shortage?

As of early 2026, Vijoice is not listed on the FDA or ASHP drug shortage databases. That means there is no officially recognized national shortage of Alpelisib.

However, "not in shortage" doesn't mean "easy to find." Vijoice is a specialty medication for an ultra-rare disease, and its distribution model is fundamentally different from common prescriptions. Many patients experience difficulty accessing it—not because of a supply problem, but because of how the medication is distributed and covered by insurance.

If you're struggling to fill your prescription, our guide on why Vijoice is so hard to find explains the factors at play.

Why Is Vijoice Hard to Find?

Even without a formal shortage, several factors make Vijoice 50 Mg 28 Day challenging to locate:

Specialty Pharmacy Distribution

Vijoice is not stocked at regular retail pharmacies. It's dispensed through a limited network of specialty pharmacies that handle complex, high-cost medications. If you're calling your local pharmacy expecting to find it, you'll come up empty.

Prior Authorization Requirements

Nearly every insurance plan requires prior authorization for Vijoice. This process can take days to weeks and involves submitting documentation of your PIK3CA gene mutation and the severity of your PROS symptoms. Delays in prior authorization are one of the most common reasons patients experience gaps in their medication supply.

Ultra-Rare Disease Population

PROS affects a very small number of patients. Because demand is low, pharmacies don't keep Vijoice on hand the way they would a common medication. This creates a just-in-time supply model where the medication is ordered specifically for each patient.

High Cost

At approximately $31,754 for a 28-day supply, pharmacies carry financial risk if they stock Vijoice without a confirmed patient and payment. This further limits where the medication is available.

How Much Does Vijoice Cost in 2026?

The cash price for Vijoice 50 Mg 28 Day remains approximately $31,754 per 28-day supply. All tablet strengths (50 mg, 125 mg, and 200 mg) and the 50 mg oral granules are priced similarly per 28-day cycle.

For most patients, paying out of pocket isn't realistic, which makes insurance coverage and financial assistance essential. Here are the main options:

• Novartis Oncology Universal Co-Pay Program: Commercially insured patients may pay as little as $0 per prescription, with Novartis covering up to $15,000 per calendar year. Call 1-877-577-7756.
• Novartis Patient Assistance Foundation (NPAF): Provides free medication for eligible uninsured or underinsured patients. Call 1-800-277-2254 or visit pap.novartis.com.
• Patient Access Network Foundation (PAN): May offer copay assistance depending on fund availability.

For a complete breakdown, read our guide on how to save money on Vijoice in 2026.

New Options and Developments

The landscape for PROS treatment continues to evolve:

• Additional Vijoice dosage forms: In addition to the original tablets, Vijoice is now available as 50 mg oral granules, which can be mixed with soft food for patients who have difficulty swallowing tablets.
• Dose optimization data: Pediatric patients aged 6 and older may now have their dose increased to 125 mg daily after 24 weeks of treatment at 50 mg, if their doctor determines it could improve their response.
• Investigational therapies: AKT inhibitors like Miransertib are in clinical trials and could eventually offer another treatment option for PROS patients.

To learn about alternatives currently available, see our article on alternatives to Vijoice if you can't fill your prescription.

How to Find Vijoice in Stock Right Now

If you need to fill your Vijoice prescription, here are the most effective steps:

1. Search Medfinder — Check for Vijoice 50 Mg 28 Day availability by location.
2. Contact your specialty pharmacy — If you already have one assigned, call them directly about your refill timeline.
3. Call Novartis patient support at 1-877-577-7756 — They can help navigate pharmacy and insurance issues.
4. Check your prior authorization status — If this is a new prescription or annual renewal, prior authorization may be pending.
5. Start refills early — Begin the refill process at least 2 weeks before your supply runs out.

For a step-by-step guide, read how to find Vijoice in stock near you.

Final Thoughts

Vijoice 50 Mg 28 Day is not in a formal shortage in 2026, but its specialty distribution model, high cost, and prior authorization requirements mean that accessing it takes more planning than most medications. The key is to work closely with your specialist, use a specialty pharmacy, take advantage of Novartis financial assistance programs, and plan refills well in advance.

If you're new to Vijoice, our overview of what is Vijoice: uses, dosage, and what you need to know is a great starting point.