Sunosi Shortage Update: What Patients Need to Know in 2026

If you've been struggling to fill your Sunosi prescription, you're not alone — and you may be wondering whether there's an official shortage. Here's the latest on Sunosi availability in 2026, including what the FDA says, why stocking gaps happen, and what you can do to protect your supply.

Current Shortage Status: Is Sunosi in an FDA Shortage in 2026?

As of 2026, Sunosi (solriamfetol) is NOT on the FDA's official drug shortage list. The FDA's shortage database tracks medically necessary drugs where demand significantly outpaces supply, and Sunosi does not currently meet that threshold. However, patients routinely report localized stocking gaps — meaning individual pharmacies may have difficulty obtaining Sunosi at any given time, even if there is no national shortage.

What Changed: Jazz to Axsome Transition

Sunosi was originally approved in March 2019 by Jazz Pharmaceuticals. In a significant change for patients, distribution of Sunosi in the United States was transferred to Axsome Therapeutics. Transitions in drug distribution can temporarily disrupt the supply chain as wholesalers and pharmacies adjust their ordering processes. If you experienced difficulty filling Sunosi during this transition, you're not imagining it — distribution changes routinely cause temporary localized availability gaps.

Why Sunosi Availability Varies by Pharmacy

Even without a formal shortage, stocking gaps are common for several reasons:

No generic version: Sunosi is a brand-only drug with no generic equivalent (expected no sooner than 2042). Pharmacies stock brand-only drugs more conservatively due to higher cost and slower turnover.

Controlled substance regulations: As a Schedule IV drug, Sunosi ordering is subject to DEA quota and reporting requirements, which limits how aggressively pharmacies can stock up.

Retail price: At approximately $1,100–$1,230 per 30-day supply, smaller pharmacies may not keep Sunosi on their shelves if they have few patients taking it.

Niche patient population: Sunosi is specifically for EDS related to narcolepsy and OSA — conditions that, while common, are often underdiagnosed and undertreated. This can mean lower per-pharmacy demand.

How to Protect Your Supply in 2026

Here's what patients taking Sunosi can do right now to reduce the risk of running out:

Build a relationship with one pharmacy: When a pharmacy knows you're a regular customer for Sunosi, they're more likely to keep it in stock. Ask your pharmacy to set you up as a standing order.

Switch to mail order: Large mail-order pharmacies maintain robust inventory of specialty and brand-name drugs. Ask your insurer about CVS Caremark, Express Scripts, or OptumRx for 90-day supplies.

Use medfinder: If you can't find Sunosi locally, medfinder calls nearby pharmacies on your behalf to check availability and texts you the results.

Ask your doctor about back-up options: Discuss what you should do if Sunosi becomes unavailable. Having a contingency plan — like a trial of generic modafinil — is good preparation.

Start refill searches early: Begin searching for your next fill when you have 7–10 days of medication left. For controlled substances, new prescriptions can sometimes take a few extra days to process.

What to Do If You Run Out of Sunosi

If you run out of Sunosi and can't find it quickly, contact your prescriber right away. Good news: clinical studies showed Sunosi does not produce withdrawal symptoms upon abrupt discontinuation. However, your EDS symptoms will return without medication, which can be dangerous — especially if you drive or operate machinery. Your doctor may prescribe a short bridge of modafinil while you secure your Sunosi supply.

Finding Sunosi Near You

Don't spend hours on the phone. medfinder calls pharmacies in your area to check which ones have Sunosi in stock, and texts you the results. See also our guide on how to find Sunosi in stock near you for step-by-step strategies.