The Pregnyl Shortage in 2026: Where Things Stand

If you rely on Pregnyl (human chorionic gonadotropin) for fertility treatment or hormone therapy, you've probably noticed it's been hard to find. The shortage of hCG products — including Pregnyl — has been an ongoing issue for several years now, and patients heading into 2026 deserve a clear picture of what's happening.

Here's your updated guide to the Pregnyl shortage: what's causing it, whether it's getting better, what it costs right now, and what you can do to get your medication.

Is Pregnyl Still in Shortage?

Yes. As of early 2026, Pregnyl and other hCG injectable products remain intermittently available. Some pharmacies have stock; many don't. The situation has improved somewhat from the worst periods of the shortage, but it hasn't fully resolved.

The FDA Drug Shortages database has listed various hCG products on and off since 2020. The core problems — limited manufacturers, complex biological production, and growing demand — haven't gone away.

What this means for you: availability depends heavily on where you are and which pharmacy you use. Checking real-time stock with a tool like Medfinder is the best way to find what's available near you today.

Why Is Pregnyl Hard to Find?

We've covered this in depth in our article on why Pregnyl is so hard to find, but here's the summary:

• Biological manufacturing complexity: Pregnyl's hCG is derived from the urine of pregnant women, making production inherently more variable and harder to scale than synthetic drugs.
• Few manufacturers: Only a small number of companies produce injectable hCG (Organon for Pregnyl, Ferring for Novarel, EMD Serono for Ovidrel). Any single manufacturer's issue impacts the whole market.
• Rising fertility treatment demand: More patients are undergoing IVF and other assisted reproduction each year, increasing demand for hCG trigger shots.
• Regulatory changes: FDA enforcement actions on compounded hCG products have removed some supply from the market.

How Much Does Pregnyl Cost in 2026?

The cost of Pregnyl depends on whether you have insurance coverage for fertility medications:

• Without insurance: $100-$250 per 10,000 unit vial at most pharmacies
• With insurance: Varies widely. Some plans cover fertility medications fully or with a copay; others exclude them entirely. Prior authorization may be required.
• Generic hCG: $80-$200 per 10,000 unit vial, potentially a savings over brand-name Pregnyl
• Ovidrel (alternative): $100-$250 per pre-filled syringe

For tips on reducing your out-of-pocket costs, see our guide on how to save money on Pregnyl.

Are There New Options for Patients?

While no brand-new hCG products have launched recently, patients do have more awareness of their options than before:

• Recombinant hCG (Ovidrel) remains available and is sometimes easier to find than urinary-derived products like Pregnyl.
• Lupron triggers have become more widely accepted in IVF protocols, especially for patients at high risk of ovarian hyperstimulation syndrome (OHSS).
• Real-time stock tools like Medfinder make it much easier to locate available inventory without spending hours on the phone.

For a detailed comparison of alternatives, read our post on alternatives to Pregnyl.

How to Find Pregnyl in Stock Right Now

Here are your best strategies for finding Pregnyl today:

1. Check Medfinder for real-time pharmacy stock near your location.
2. Contact specialty pharmacies that focus on fertility medications — they often have better supply access.
3. Ask your fertility clinic if they have an in-house pharmacy or preferred pharmacy partner with reliable stock.
4. Consider mail-order specialty pharmacies that can ship overnight for time-sensitive cycles.
5. Plan ahead: If you know you'll need Pregnyl in an upcoming cycle, start looking 1-2 weeks early.

For more detailed strategies, see our guide on how to find Pregnyl in stock near you.

Final Thoughts

The Pregnyl shortage isn't over, but it's manageable with the right information and tools. The situation in 2026 is one of inconsistent availability rather than complete unavailability — meaning the medication is out there, but finding it takes more effort than it should.

Stay proactive: use Medfinder to check stock, communicate early with your care team, and know your alternatives. If you're a provider looking for clinical guidance on managing this shortage, check out our provider-focused shortage update.

We'll continue updating this page as the situation evolves. You shouldn't have to navigate a drug shortage alone.