Learn how to reduce the cost of Nitroglycerin with discount cards, coupons, patient assistance programs, and money-saving tips for 2026.
If you take Nitroglycerin for chest pain or angina, you know it's an essential medication — not something you can skip. But depending on your formulation and insurance status, the cost can add up. And with the ongoing Nitroglycerin shortage, some patients are paying more than usual because their affordable generic isn't available and they need a pricier brand-name product.
The good news? There are several ways to reduce what you pay for Nitroglycerin. This guide covers coupons, discount cards, patient assistance programs, and other strategies to help you save money in 2026.
Nitroglycerin pricing varies widely depending on the formulation:
If you have insurance, your copay will likely be much lower — especially for generic formulations, which are typically Tier 1 or Tier 2 on most formularies. But if you're uninsured, underinsured, or stuck buying a brand-name product due to the shortage, these prices can be a real burden.
Prescription discount cards are one of the easiest ways to save on Nitroglycerin. These free programs negotiate lower prices with pharmacies and can save you 20-80% off the cash price. Here are the top options:
GoodRx is one of the most popular prescription discount platforms. Simply search for "Nitroglycerin," select your formulation and dosage, enter your zip code, and compare prices at pharmacies near you. GoodRx often shows generic sublingual tablets for $10-$25 and patches starting around $15-$40/month. Show the coupon on your phone at the pharmacy counter.
SingleCare offers competitive pricing and is accepted at most major pharmacy chains. It's free to use and doesn't require insurance. SingleCare prices for Nitroglycerin are often comparable to or better than GoodRx depending on your pharmacy.
RxSaver compares prices across multiple discount programs to find you the best deal. It's a good tool to use alongside GoodRx and SingleCare since prices vary by pharmacy and program.
Additional options to check include:
Pro tip: Prices vary between discount programs and pharmacies. Check at least 2-3 programs and compare prices at different pharmacies before filling. A few minutes of comparison shopping can save you $20-$50 or more.
If you're uninsured or have very limited income, patient assistance programs may provide Nitroglycerin for free or at a very low cost:
Pfizer manufactures Nitrostat and offers the Pfizer RxPathways program for eligible patients. This program can help uninsured or underinsured patients access Pfizer medications at reduced cost or no cost. Eligibility typically requires:
Apply online at pfizerrxpathways.com or call their toll-free number for assistance.
NeedyMeds is a comprehensive database of patient assistance programs, discount drug cards, and other resources. Search for "Nitroglycerin" to find all available programs based on your specific formulation and financial situation.
RxAssist provides a searchable database of manufacturer and charitable patient assistance programs. It's especially useful for finding programs you might not discover through a simple web search.
Many states offer pharmaceutical assistance programs (SPAPs) for low-income residents, particularly seniors. These programs may cover or subsidize the cost of Nitroglycerin. Check with your state's health department or aging services department.
When your doctor writes a prescription, make sure it allows for generic substitution. Generic Nitroglycerin sublingual tablets and patches are significantly cheaper than brand-name products and are equally effective. If your pharmacist offers the brand and you have a choice, always request the generic.
Prices for the same medication can vary dramatically between pharmacies — even pharmacies on the same street. Use MedFinder to find pharmacies with Nitroglycerin in stock, and then compare prices using GoodRx or SingleCare. Consider:
If you use Nitroglycerin patches for daily angina prevention, a mail-order pharmacy through your insurance plan may offer 90-day supplies at a lower per-unit cost than retail. This works best for maintenance medications you take regularly.
Even at retail pharmacies, filling a 90-day supply is often cheaper per unit than filling 30 days at a time. Ask your doctor to write the prescription for a 90-day supply and check if your pharmacy or insurance offers a discount for larger fills.
If you have insurance, review your plan's formulary (list of covered drugs) to see which Nitroglycerin formulations are covered and at what tier. Generic sublingual tablets and patches are usually Tier 1 (lowest copay). If you're being forced to use a brand-name product due to the shortage, ask your doctor to submit a prior authorization or formulary exception request to get it covered at a lower tier.
Most Medicare Part D plans cover generic Nitroglycerin at low copays. If you're in the coverage gap ("donut hole"), discount cards may offer better prices than your plan's gap coverage. Compare your Part D price with GoodRx before filling.
Medicaid typically covers Nitroglycerin with minimal or no copay. If you're on Medicaid and having trouble accessing Nitroglycerin due to the shortage, contact your Medicaid managed care plan for help locating a pharmacy with stock.
If you normally use an affordable generic that's currently unavailable, and you're forced to buy a more expensive brand or alternative formulation, try these steps:
Nitroglycerin is a lifesaving medication, and cost should never be a barrier to access. Between discount cards, patient assistance programs, generic options, and smart pharmacy shopping, most patients can find significant savings. Start by checking prices on GoodRx or SingleCare, and use MedFinder to find pharmacies with stock at the best prices.
For more information about Nitroglycerin, explore our related articles:
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