Crinone Is Expensive — But You Don't Have to Pay Full Price

If you've seen the price tag on Crinone, you probably did a double take. At retail pharmacies, a single box of 15 applicators of Crinone 8% can cost anywhere from $450 to $700 without insurance. And since many fertility patients need Crinone for 10-12 weeks during an IVF cycle, the total cost can add up to thousands of dollars.

The good news? Most patients can pay significantly less with the right approach. Here's how to save money on Crinone in 2026.

How Much Does Crinone Cost Without Insurance?

Let's start with the numbers. Here's what you might pay for Crinone 8% (90 mg, 15 applicators) at different types of pharmacies without insurance:

• Major chain pharmacies (CVS, Walgreens): $550-$700
• Retail with GoodRx Gold coupon: ~$453
• Independent pharmacies: $450-$600
• Specialty IVF pharmacies: $65-$100

Yes, you read that right — specialty IVF pharmacies can offer Crinone for as little as $65 for 15 applicators, a fraction of the retail price. The price difference is enormous, and it's one of the most impactful ways to save.

Coupons and Discount Cards

If you're filling at a retail pharmacy, discount cards can take a significant chunk off the price:

GoodRx

GoodRx offers free coupons that can bring Crinone 8% (15 applicators) down to approximately $453 at participating pharmacies. GoodRx Gold members may see additional savings. Simply search for "Crinone" on the GoodRx website or app, compare prices at pharmacies near you, and show the coupon at checkout.

SingleCare

SingleCare is another free discount card that may offer competitive pricing on Crinone at certain pharmacies. Prices vary by location, so it's worth comparing with GoodRx.

Other Discount Card Options

Several other services offer prescription discount cards that may help with Crinone pricing:

• Optum Perks (perks.optum.com)
• RxSaver (rxsaver.com)
• BuzzRx (buzzrx.com)
• ScriptSave WellRx (wellrx.com)

Prices vary between discount cards and pharmacies, so compare 2-3 options before filling. These cards are free to use and can't be combined with insurance — use whichever gives you the lower price.

Patient Assistance Programs

If the cost of Crinone is a financial hardship, patient assistance programs (PAPs) may be able to help:

The Rx Advocates

The Rx Advocates offers a patient assistance program that provides Crinone for approximately $80 per month. They handle the application process on your behalf and work directly with the manufacturer's assistance programs. Eligibility is typically based on income and insurance status.

NeedyMeds

NeedyMeds maintains a database of patient assistance programs and discount options for medications including Crinone. Search their site for current programs available in your state.

RxAssist

RxAssist is another comprehensive database of patient assistance programs, including those for specialty and fertility medications. It's free to search and can help you identify programs you may qualify for.

Fertility Clinic Programs

Many fertility clinics have in-house financial counselors or medication assistance coordinators who can help you access discounted medications. Ask your clinic about any partnerships with specialty pharmacies or financial assistance options.

Other Ways to Save on Crinone

Use a Specialty IVF Pharmacy

This is the single biggest money-saver. Specialty IVF pharmacies like DiscountIVFMeds and others sell Crinone 8% for as little as $65 for 15 applicators — saving you $400-$600 per box compared to retail. Many offer mail-order shipping and accept prescriptions from any provider.

Ask your fertility clinic for their recommended specialty pharmacy, or use Medfinder to compare options near you.

Ask About Generic Progesterone Gel

A generic version of Progesterone vaginal gel is available, though not all pharmacies carry it. When it's in stock, generic Progesterone gel typically costs $200-$400 for 15 applicators — still expensive, but less than brand-name Crinone at retail. Ask your pharmacist if the generic is available, or if they can order it.

Consider Lower-Cost Progesterone Alternatives

If cost is a major barrier, ask your doctor whether a different form of Progesterone could work for your treatment. Some much more affordable options include:

• Generic Prometrium capsules (used vaginally): Starting at $12-$30 with a discount coupon — the most affordable Progesterone option available
• Progesterone in Oil injections: $20-$50 per vial — highly effective, though injections can be uncomfortable
• Compounded Progesterone suppositories: Varies by compounding pharmacy, but often $50-$150 per month

These alternatives are well-established in fertility medicine and may be appropriate depending on your specific treatment protocol. Read more in our guide to alternatives to Crinone.

Check Your Insurance Coverage

If you have insurance that covers fertility treatments, Crinone may be partially or fully covered. Key things to check:

• Does your plan have a fertility benefit? Plans in states with fertility mandates (like Massachusetts, Connecticut, Illinois, and New York) are more likely to cover fertility medications.
• Is Crinone on your formulary? Check your plan's drug formulary or call your insurance company's pharmacy benefits line.
• Is prior authorization required? If so, have your doctor submit it as early as possible to avoid delays.
• Is there a preferred pharmacy? Some plans require you to use a specific specialty pharmacy to get the best copay.

Ask Your Clinic About Leftover Medication Programs

Some fertility clinics have programs where patients who have completed their treatment can donate unused, sealed medication to patients in need. This isn't available everywhere, but it's worth asking about — especially for expensive medications like Crinone.

Final Thoughts

Crinone doesn't have to break the bank. The single most impactful step is filling at a specialty IVF pharmacy, where prices can be 85-90% lower than retail. Beyond that, discount cards, patient assistance programs, and generic alternatives all provide pathways to make Progesterone support more affordable.

Start by checking availability and pricing on Medfinder. And for more information about Crinone, explore our guides on what Crinone is, Crinone side effects, and Crinone drug interactions.