How to Save Money on Combigan in 2026: Coupons, Discounts, and Patient Assistance

Brand-name Combigan (brimonidine tartrate/timolol maleate) can cost over $278 for a single 5 mL bottle without insurance — and if you need one bottle per month for each eye, that adds up fast. The good news: there are several legitimate ways to significantly reduce your out-of-pocket cost in 2026, whether you have insurance or not.

Option 1: Switch to Generic Combigan (Biggest Savings)

The most effective way to lower your Combigan cost is to use the generic version: brimonidine tartrate/timolol maleate ophthalmic solution 0.2%/0.5%. FDA-approved since April 2022, the generic is therapeutically equivalent to brand Combigan and widely available at a fraction of the price.

With a GoodRx coupon, the generic is available for as low as $24–$34 at many pharmacies. SingleCare offers prices as low as $19–$28. Talk to your eye doctor about switching — for most patients, the generic works just as well as the brand name.

Option 2: AbbVie AYS Co-Pay Assistance Program (For Insured Patients)

AbbVie offers a co-pay assistance program called "AYS" (At Your Service) specifically for Combigan. Here's how it works:

• Eligible patients: Commercially insured patients only. NOT available for Medicare, Medicaid, or other government-funded insurance.
• How much you save: Eligible patients may pay as little as $30 per 30-day supply. Maximum annual benefit of $2,160 for Combigan.
• How to enroll: Call 833-342-5297, text SAVINGS to 72428, or visit the AbbVie AYS website. Ask your eye doctor's office for a savings card — they may have them on hand.

Option 3: GoodRx and SingleCare Discount Cards

Discount cards like GoodRx and SingleCare work by negotiating lower prices with pharmacies on your behalf. They're free to use and available to anyone — no insurance required.

• GoodRx: Generic brimonidine/timolol from as low as $24 at participating pharmacies. Check goodrx.com for current prices at pharmacies near you.
• SingleCare: Generic brimonidine/timolol as low as $19 with a SingleCare coupon. Brand Combigan as low as $28 at select pharmacies.

Important: You generally cannot use a discount card at the same time as insurance. Check which gives you the lower price and use that at the counter.

Option 4: myAbbVie Assist (Patient Assistance for Uninsured Patients)

If you are uninsured or underinsured and cannot afford Combigan, AbbVie's patient assistance program — myAbbVie Assist — may be able to help you receive the medication at reduced or no cost. Eligibility is based on income and insurance status.

Visit abbvieaccess.com/patient-assistance or ask your eye doctor's office to help you apply. This program requires a physician to certify medical necessity.

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Option 5: Use Mail Order for 90-Day Supply Savings

Many insurance plans offer a reduced copay when you order a 90-day supply through a mail-order pharmacy. If your plan allows this, ask your eye doctor to write a 90-day prescription. Mail order also ensures consistent access without monthly pharmacy trips, which reduces the risk of access gaps.

Option 6: Check if Your Insurance Requires Prior Authorization

If Combigan requires prior authorization on your plan and the PA hasn't been submitted, your insurance will deny the claim — meaning you either pay full price or go without. Contact your eye doctor's office and ask them to submit a PA for Combigan. Once approved, your normal copay applies.

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Quick Savings Comparison

Here's how the options stack up for a 5 mL bottle (approximately 1 month's supply for one eye):

• Brand Combigan (no insurance, no coupon): ~$278
• Brand Combigan with AbbVie AYS (insured): As low as $30
• Generic with GoodRx (no insurance): ~$24–$34
• Generic with SingleCare (no insurance): As low as $19
• Insurance copay (generic, Tier 1–2): $0–$30

Whatever savings strategy you use, make sure you can actually find Combigan in stock at the pharmacy where you plan to use your coupon. medfinder can help you quickly locate which nearby pharmacies have it available.