Your Lupron Injection Is Due — But No One Has It in Stock

If you've been searching for Lupron Depot and coming up empty, you already know how stressful it is. This isn't a medication you can just skip. Whether you're being treated for prostate cancer, endometriosis, uterine fibroids, or your child needs it for central precocious puberty, staying on schedule matters.

Lupron Depot (Leuprolide Acetate) is a specialty injectable made by AbbVie. It's administered by a healthcare provider every 1 to 6 months depending on the formulation. Because it's a brand-only, single-manufacturer product with a history of supply disruptions, finding it in stock can be a real challenge.

But there are things you can do. Here are three proven strategies — plus what to try if you've exhausted your options.

Tip 1: Use Medfinder to Search for Lupron in Real Time

Medfinder is a free tool designed to help patients find medications that are hard to locate. Instead of calling pharmacy after pharmacy, you can search for Lupron Depot availability near you in one place.

Here's how it works:

1. Go to medfinder.com
2. Search for "Lupron Depot" and select the specific strength you need (3.75 mg, 7.5 mg, 11.25 mg, 22.5 mg, 30 mg, or 45 mg)
3. Enter your zip code
4. See which pharmacies and provider offices near you have it available

This is especially helpful for Lupron because it's often stocked at specialty pharmacies and provider offices that you might not think to call. Medfinder checks these locations so you don't have to do all the legwork.

Tip 2: Try Specialty and Independent Pharmacies

Lupron Depot isn't a typical retail pharmacy medication. Most patients receive their injection at a doctor's office, hospital outpatient clinic, or specialty pharmacy. Here's where to look beyond your regular provider:

• Hospital outpatient pharmacies — These often have dedicated supply lines for oncology and specialty drugs and may have stock when community practices don't.
• Specialty pharmacies — Pharmacies that focus on injectable and specialty medications often have better relationships with distributors and can source hard-to-find drugs.
• Oncology and urology clinics — Larger practices that see many Lupron patients may maintain their own inventory and could potentially treat you even if you're not a regular patient (call ahead to ask).
• Independent pharmacies — Some independent pharmacies have access to secondary distributors or can special-order medications that chain pharmacies can't easily get.

Don't be afraid to expand your search radius. A provider 30 minutes away that has Lupron in stock is better than your usual office with no supply.

Tip 3: Plan Ahead and Communicate Early

One of the best things you can do is get ahead of the problem. If you know your next Lupron injection is due in 4 weeks, start the process now:

• Call your provider's office 2-4 weeks before your injection date and ask them to confirm they have your specific strength in stock or on order.
• Ask about ordering timelines. Some offices order from specialty distributors with 1-2 week lead times. If they know early, they can plan accordingly.
• Request that your provider check multiple distributors. Availability can vary between McKesson, Cardinal Health, AmerisourceBergen, and other distributors.
• Keep your insurance authorization current. Lupron Depot typically requires prior authorization. An expired auth can delay ordering even when supply is available.

What If You Still Can't Find Lupron?

If you've tried the strategies above and still can't locate Lupron Depot, here are additional options:

Ask Your Doctor About Alternatives

Several other GnRH agonists and antagonists may work for your condition. Read our full guide on alternatives to Lupron. Options include:

• Eligard — Same active ingredient (Leuprolide Acetate), delivered subcutaneously instead of intramuscularly
• Zoladex (Goserelin) — A GnRH agonist implant approved for prostate cancer, breast cancer, and endometriosis
• Trelstar (Triptorelin) — A GnRH agonist injection for prostate cancer
• Orgovyx (Relugolix) — An oral GnRH antagonist for prostate cancer (no injection needed)

Contact AbbVie Directly

AbbVie has resources for patients and providers experiencing supply issues:

• Medical Information: 1-800-633-9110
• Provider sample requests: 833-999-1779 (1-month Lupron Depot 3.75 mg samples)
• Patient assistance (myAbbVie Assist): 1-800-222-6885

Check the FDA and ASHP Shortage Databases

For the most up-to-date information on whether Lupron is officially in shortage, check:

• ASHP Drug Shortage Database
• FDA Drug Shortage Database

For a detailed breakdown of the current shortage situation, read our Lupron shortage update for 2026.

Final Thoughts

Finding Lupron Depot in stock takes more effort than most medications, but it's not impossible. The key is to start early, use the right tools, and expand your search beyond your usual provider.

Medfinder can save you hours of phone calls by showing you real-time Lupron availability near you. And if your current strength is truly unavailable, your doctor can help you explore alternatives that keep your treatment on track.

For more information about Lupron, including side effects and how it works, check out our guides on what is Lupron and Lupron side effects.