Finding Brexafemme Feels Impossible — But There Are Ways to Improve Your Odds

If you've been prescribed Brexafemme (Ibrexafungerp) for a vaginal yeast infection and can't find it at your local pharmacy, you're dealing with a problem thousands of women have faced since 2023. A nationwide recall, FDA hold, and corporate transition have made this first-in-class antifungal one of the hardest prescriptions to fill in America.

But "hard to find" doesn't always mean "impossible." In this guide, we'll walk you through practical strategies and tools to track down Brexafemme — and what to do if you still come up empty.

Understanding the Brexafemme Supply Situation

Before you start calling pharmacies, it helps to understand what you're up against. Brexafemme has been listed as temporarily unavailable by the ASHP drug shortage database since the 2023 recall. The manufacturer, Scynexis, is transferring the drug's NDA to GSK, which plans to engage with the FDA in 2026 about restarting production.

That said, some pharmacies may still have limited stock from earlier shipments, and the situation can change quickly. Staying proactive is key.

Tip 1: Use Medfinder to Search in Real Time

The fastest way to check if any pharmacy near you has Brexafemme is to use Medfinder. Medfinder lets you search for specific medications and see which pharmacies currently have them in stock — updated in real time.

Here's how to use it:

1. Go to medfinder.com
2. Type "Brexafemme" or "Ibrexafungerp" in the search bar
3. Enter your zip code or allow location access
4. Browse results to see which pharmacies near you report having the drug

This saves you the time and frustration of calling pharmacy after pharmacy. For a step-by-step walkthrough, see our guide on how to check if a pharmacy has Brexafemme in stock.

Tip 2: Try Independent and Specialty Pharmacies

Most people start at big chain pharmacies like CVS, Walgreens, or Rite Aid. But these chains often share the same supply chain and distribution network. When one is out, they all tend to be out.

Independent pharmacies are a different story. They often work with multiple wholesalers and may have access to inventory that chains don't. Here's how to find them:

• Search "independent pharmacy near me" on Google Maps
• Look for pharmacies that specialize in women's health or compounding
• Ask your doctor if they know of local pharmacies that carry harder-to-find medications

Specialty pharmacies that handle infectious disease or women's health medications may also be worth a call. They sometimes carry niche drugs that mainstream pharmacies don't stock.

Tip 3: Call During Off-Peak Hours

If you're going to call pharmacies directly, timing matters. Pharmacy staff are busiest during lunch hours and late afternoon. Try calling:

• Early morning — right when the pharmacy opens
• Mid-morning on weekdays — typically the quietest time
• Avoid Monday mornings — pharmacies are often flooded with weekend prescription transfers

When you call, be specific. Ask: "Do you currently have Brexafemme 150 mg tablets in stock?" Some technicians may need to look it up by the generic name, Ibrexafungerp. If they don't have it, ask if they can check with their wholesaler about expected restock dates.

What If You Still Can't Find Brexafemme?

If you've exhausted your local options, don't give up. Here's what to do next:

Ask Your Doctor About Alternatives

There are effective alternatives for vaginal yeast infections, depending on your situation:

• Fluconazole (Diflucan) — the most commonly prescribed oral antifungal, available as a low-cost generic ($4 to $15)
• Miconazole (Monistat) — available over the counter as a topical cream or suppository
• Oteseconazole (Vivjoa) — a newer oral option for preventing recurrent yeast infections

Read more in our post on alternatives to Brexafemme.

Sign Up for Restock Alerts

Some pharmacy tools and apps let you sign up for notifications when a medication comes back in stock. Check with your pharmacy or use Medfinder to monitor availability over time.

Talk to Your Prescriber About a Backup Plan

If you have recurrent yeast infections and were relying on Brexafemme's monthly dosing regimen, work with your doctor to create a backup treatment plan. They can help you manage symptoms while you wait for Brexafemme to return to the market. You can also find a provider experienced with this medication through our guide on finding a doctor who prescribes Brexafemme.

How Much Does Brexafemme Cost If You Find It?

If you're lucky enough to locate Brexafemme, be prepared for the price. Without insurance, a single treatment course (4 tablets) typically costs between $450 and $600. With the manufacturer's copay assistance program, eligible commercially insured patients may pay as little as $30.

For detailed pricing information and money-saving strategies, see our guide on how to save money on Brexafemme.

Final Thoughts

Finding Brexafemme in 2026 requires patience, persistence, and the right tools. Start with Medfinder for real-time availability, branch out to independent pharmacies, and have a conversation with your doctor about backup plans. The drug's supply situation is expected to improve as GSK takes over commercialization, but in the meantime, being proactive is your best strategy.