Is Doxycycline still in shortage in 2026? Get the latest update on availability, pricing, and what you can do to find your prescription.
If you've been prescribed Doxycycline in the last few years, there's a good chance you've experienced the frustration of hearing "we're out of stock" at the pharmacy counter. The Doxycycline shortage made national headlines in 2023 and continued to affect patients throughout 2024 and 2025.
So where do things stand now, in 2026? Here's what you need to know.
The situation has improved significantly compared to 2023-2024, when pharmacies across the country were running out regularly. Manufacturers have increased production, and the FDA has worked to bring additional supply to market.
However, Doxycycline is not completely out of the woods. Spot shortages — where individual pharmacies or regions run low on specific formulations — continue to happen. The most affected products include:
If you're having trouble finding Doxycycline, Medfinder can help you locate pharmacies near you with current stock.
The shortage has roots in several overlapping problems:
Starting in 2023, public health authorities began recommending Doxycycline as post-exposure prophylaxis for sexually transmitted infections — known as DoxyPEP. This new use created a massive, unexpected surge in demand. Millions of new prescriptions were written for a drug whose supply chain was calibrated for traditional uses.
Doxycycline production depends on a limited number of raw material suppliers, most based overseas. When any of these suppliers experience disruptions — quality issues, factory shutdowns, or export restrictions — the entire U.S. supply chain feels the impact.
Only a handful of manufacturers produce generic Doxycycline for the U.S. market. Companies like Hikma, Par Pharmaceutical, Lupin, and Amneal make up the bulk of supply. When even one manufacturer has a problem, it can create a significant gap.
Doxycycline has a history of dramatic price swings. In 2013, prices spiked from around $20 per bottle to over $1,800, drawing attention to how fragile the generic drug supply chain can be. While prices have stabilized, the underlying market dynamics that caused those swings haven't fully been resolved.
The good news is that when you can find it, generic Doxycycline remains relatively affordable:
Most insurance plans cover generic Doxycycline on their lowest tier with no prior authorization required. If you're paying out of pocket, check our guide on how to save money on Doxycycline.
Several positive developments have helped improve the Doxycycline supply picture:
If you need Doxycycline today, here's what to do:
For a complete guide, read our article on how to find Doxycycline in stock near you.
If you've exhausted all options and truly cannot find Doxycycline, talk to your doctor about alternatives. Depending on your condition:
Learn more in our guide to alternatives to Doxycycline.
The Doxycycline shortage of 2023-2024 was one of the most disruptive antibiotic shortages in recent memory. While 2026 looks much better, the supply chain for this essential medication remains somewhat fragile. Spot shortages can still happen, and patients need to be prepared.
Stay informed, use tools like Medfinder to track availability, and work closely with your doctor and pharmacist. If you plan ahead and know your options, you'll be in a much better position to get the medication you need when you need it.
You focus on staying healthy. We'll handle the rest.
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