Cefpodoxime in 2026: What's the Current Situation?

If you've recently been prescribed cefpodoxime and had trouble getting it filled, you're dealing with a problem that's affected patients across the U.S. for several years. The cefpodoxime shortage — particularly the oral suspension (liquid) form — has been an ongoing challenge since 2018. Here's everything you need to know about the current state of cefpodoxime availability in 2026.

Is Cefpodoxime Still in Shortage?

The short answer: it depends on the formulation.

• Cefpodoxime tablets (100 mg and 200 mg) are generally available at most pharmacies, though spot shortages can occur during peak respiratory illness season.
• Cefpodoxime oral suspension (50 mg/5 mL and 100 mg/5 mL) has been on the ASHP (American Society of Health-System Pharmacists) drug shortage list intermittently. This is the form most commonly prescribed for children, and it has been harder to find consistently.

The suspension shortage has been driven largely by manufacturer exits. Aurobindo discontinued its cefpodoxime oral suspension product, leaving fewer companies to supply the entire U.S. market.

Why Is Cefpodoxime Hard to Find?

Several factors contribute to the ongoing availability issues:

Fewer Manufacturers

With the brand-name product Vantin long discontinued and Aurobindo exiting the oral suspension market, only a small number of generic manufacturers remain. Less competition means less production capacity and more vulnerability to disruptions.

Raw Material Sourcing

The active pharmaceutical ingredients for cefpodoxime are primarily manufactured overseas. Regulatory inspections, export restrictions, and shipping disruptions can all interrupt the supply chain.

Seasonal Demand

Cefpodoxime treats infections that peak in fall and winter — ear infections, sinus infections, bronchitis, and strep throat. When prescriptions surge, available supply gets stretched thin.

For a deeper dive, read our article on why cefpodoxime is so hard to find.

How Much Does Cefpodoxime Cost in 2026?

Cefpodoxime is available only as a generic, which helps keep costs manageable — but prices can still vary significantly:

• Without insurance or coupons: A typical course (14-20 tablets of 200 mg) costs $50 to $175 at retail pharmacies.
• With a discount card: Using GoodRx, SingleCare, or similar coupon programs can bring the cost down to $15 to $30 for the same course.
• With insurance: Most plans cover cefpodoxime as a Tier 1 or Tier 2 generic, with copays typically $0 to $15.

The oral suspension tends to cost more per course, with retail prices ranging from $60 to $200+ depending on the strength and quantity. Discount cards can help here too. For detailed savings strategies, see how to save money on cefpodoxime.

Are There New Options in 2026?

While no new brand-name versions of cefpodoxime have launched, the generic landscape continues to evolve. More generic manufacturers may enter the market as demand stays high and existing players face supply challenges. Additionally, compounding pharmacies can prepare liquid formulations of cefpodoxime for patients (especially children) who need the suspension when commercial products are unavailable.

If cefpodoxime isn't available, several other antibiotics can treat the same infections effectively. Learn more in our guide to cefpodoxime alternatives.

How to Find Cefpodoxime in Stock

Here are your best options for tracking down cefpodoxime right now:

1. Use Medfinder to search for real-time pharmacy availability near your zip code.
2. Check independent pharmacies — they often have different supply channels than big chains.
3. Call ahead before driving to any pharmacy. Confirm they have your specific formulation and strength.
4. Ask about partial fills — start your course now and get the rest when more stock arrives.
5. Consider mail-order pharmacies for non-urgent prescriptions.

For step-by-step guidance, read how to find cefpodoxime in stock near you.

Final Thoughts

The cefpodoxime shortage in 2026 is a nuisance, but it's manageable. Tablets remain widely available, the oral suspension is recovering, and effective alternatives exist if you need them. Stay proactive — use real-time tools like Medfinder, communicate with your pharmacist and doctor, and explore discount programs to keep costs down.

Your infection shouldn't have to wait because of a supply chain issue. With the right approach, you can get the treatment you need.