Afinitor Shortage Update: What Patients Need to Know in 2026

Updated:

March 25, 2026

Author:

Peter Daggett

Summarize this blog with AI:

Is Afinitor still hard to find in 2026? Get the latest shortage update on Everolimus, including costs, new generic options, and how to find it in stock.

Afinitor Shortage Update: What Patients Need to Know in 2026

If you've been struggling to find Afinitor (Everolimus) at your pharmacy, you're probably wondering: is there an actual shortage? Or is something else going on?

The answer is more nuanced than a simple yes or no. In this update, we'll break down the current supply situation for Afinitor in 2026, explain why it can be so hard to fill, cover the costs you can expect, and give you actionable steps to get your medication without interrupting your treatment.

Is Afinitor Still in Shortage in 2026?

As of early 2026, there is no official FDA-listed shortage of Afinitor or generic Everolimus. The FDA's Drug Shortage Database does not list Everolimus as currently in shortage.

However — and this is important — many patients still report difficulty finding Afinitor at their pharmacy. This disconnect happens because Afinitor's supply challenges aren't driven by a traditional manufacturing shortage. They're driven by the drug's specialty status, limited distribution channels, and insurance barriers.

In other words: the drug exists. Getting it into your hands is the hard part.

Why Is Afinitor Hard to Find?

Several factors make Afinitor more difficult to obtain than a typical prescription:

Specialty Pharmacy Requirements

Afinitor is classified as a specialty medication. Most insurance plans require it to be dispensed through a designated specialty pharmacy — not your local CVS or Walgreens. This means you can't just walk in with a prescription and pick it up. The medication has to be ordered, verified, and shipped through specific channels.

Prior Authorization Delays

Nearly every insurance plan requires prior authorization before covering Afinitor. This involves your doctor submitting clinical documentation proving the drug is medically necessary. The process can take days to weeks, and initial requests are sometimes denied, requiring appeals. During this time, patients go without medication.

High Cost Limits Stocking

Brand-name Afinitor costs between $18,413 and $19,260 for a 28-day supply. At that price point, pharmacies take on enormous financial risk by keeping it in inventory. Most pharmacies only order it once they have a confirmed, paid prescription in hand.

Formulation-Specific Issues

Even when generic Everolimus tablets are available, specific strengths or the Afinitor Disperz dispersible formulation may be harder to find. Not all generic manufacturers produce every strength, and Disperz has fewer generic alternatives. For detailed information on formulations, see What Is Afinitor? Uses, Dosage, and What You Need to Know.

What Does Afinitor Cost in 2026?

The cost landscape for Afinitor has shifted significantly with the availability of generics:

  • Brand-name Afinitor: $18,413–$19,260 per 28-day supply (approximately $220,000–$230,000 per year)
  • Generic Everolimus (with discount card): As low as $90 per month with GoodRx Gold
  • Generic Everolimus (cash price): Approximately $4,030 per 28-day supply without discount cards
  • Afinitor Disperz (brand): Approximately $11,587 per 28-day supply at retail

The availability of generic Everolimus has been a game-changer for patients paying out of pocket. If you're currently paying full price for brand-name Afinitor, ask your doctor about switching to the generic. For all your savings options, see How to Save Money on Afinitor in 2026.

New Options and Developments in 2026

Generic Everolimus Expansion

In January 2025, the FDA granted final approval to Breckenridge Pharmaceutical for generic Everolimus Tablets for Oral Suspension (the Disperz equivalent) in 2 mg, 3 mg, and 5 mg strengths. This means patients who need the dispersible formulation now have a generic option, which should improve both availability and affordability.

Multiple generic manufacturers now produce Everolimus tablets, increasing competition and driving prices down. This is especially helpful for patients who are uninsured or facing high specialty-tier copays.

Novartis Patient Support Programs

Novartis continues to offer two key assistance programs:

  • Novartis Oncology Universal Co-pay Program: Eligible commercially insured patients may pay as little as $0 out-of-pocket, with up to $15,000 in annual assistance
  • Novartis Patient Assistance Foundation (NPAF): Provides Afinitor free of charge to eligible uninsured or underinsured patients. Apply at pap.novartis.com or call 1-800-277-2254

How to Find Afinitor in Stock Right Now

If you need Afinitor today, here's your action plan:

  1. Search on Medfinder — Check real-time pharmacy availability for Everolimus near your zip code
  2. Ask about generic Everolimus — It's the same active ingredient at a fraction of the price and may be more widely stocked
  3. Contact your specialty pharmacy — If your insurance requires a specific pharmacy, call them directly to confirm stock and shipping timeline
  4. Talk to your oncologist's office — They often have relationships with pharmacies that keep Afinitor in stock and may have bridge supplies
  5. Apply for patient assistance — If cost is the barrier, Novartis programs can help

For more detailed strategies, see our guide: How to Find Afinitor in Stock Near You (Tools + Tips).

Final Thoughts

While there's no official FDA shortage of Afinitor in 2026, the drug remains difficult to obtain because of its specialty status, high cost, and insurance complexities. The good news is that generic Everolimus is more widely available than ever — including a new generic Disperz equivalent approved in 2025 — and patient assistance programs can reduce costs dramatically.

If you're having trouble finding Afinitor, start with Medfinder and work with your doctor's office to explore all your options. Treatment interruptions for a cancer medication are serious — don't let pharmacy logistics stand in the way of your care.

Is there an official FDA shortage of Afinitor in 2026?

No. As of early 2026, the FDA does not list Afinitor or generic Everolimus as being in shortage. However, many patients still have difficulty obtaining it because it is a specialty medication with limited distribution channels, high costs, and insurance prior authorization requirements.

Has the price of Afinitor changed in 2026?

Brand-name Afinitor still costs approximately $18,413 to $19,260 per 28-day supply. However, generic Everolimus is now available for as low as $90 per month with discount cards like GoodRx Gold. A new generic version of Afinitor Disperz was also approved in early 2025, improving access to the dispersible formulation.

Will my insurance cover generic Everolimus instead of brand-name Afinitor?

Most commercial insurance plans prefer generic Everolimus because it costs less. However, coverage varies by plan, and prior authorization is still typically required. Some Medicare plans cover brand-name Afinitor but may not cover the generic, or vice versa. Contact your insurance plan's specialty pharmacy department to confirm your coverage.

What should I do if I run out of Afinitor before I can get a refill?

Contact your oncologist's office immediately. Do not stop treatment without medical guidance. Your doctor may be able to provide samples, adjust your treatment plan temporarily, or expedite a refill through a different pharmacy. You can also check Medfinder for pharmacies that have Everolimus in stock right now.

Why waste time calling, coordinating, and hunting?

You focus on staying healthy. We'll handle the rest.

Try Medfinder Concierge Free

Medfinder's mission is to ensure every patient gets access to the medications they need. We believe this begins with trustworthy information. Our core values guide everything we do, including the standards that shape the accuracy, transparency, and quality of our content. We’re committed to delivering information that’s evidence-based, regularly updated, and easy to understand. For more details on our editorial process, see here.

25,000+ have already found their meds with Medfinder.

Start your search today.
      What med are you looking for?
⊙  Find Your Meds
99% success rate
Fast-turnaround time
Never call another pharmacy