Comprehensive medication guide to Novarel including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Estimated Insurance Pricing
$30–$100 copay with fertility coverage; prior authorization usually required, and fertility drug coverage varies by state.
Estimated Cash Pricing
$150–$500+ per vial retail; as low as $150–$285 with GoodRx or discount cards depending on strength.
Medfinder Findability Score
35/100
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Novarel is a brand-name injectable form of human chorionic gonadotropin (hCG), a hormone naturally produced by the placenta during pregnancy. It is manufactured by Ferring Pharmaceuticals and belongs to the gonadotropin drug class.
Novarel is FDA-approved for:
It is also widely used off-label as an IVF trigger shot, for luteal phase support in fertility treatment, and for male infertility and testosterone preservation.
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Novarel contains human chorionic gonadotropin (hCG), which mimics the body's natural luteinizing hormone (LH). It binds to the LH/hCG receptor on ovarian cells, stimulating late follicular maturation, triggering ovulation, and supporting corpus luteum development.
In males, hCG stimulates Leydig cells in the testes to produce testosterone, which promotes testicular descent in cases of cryptorchidism and supports spermatogenesis in hypogonadotropic hypogonadism.
5,000 USP Units
Lyophilized powder for injection with 10 mL diluent
10,000 USP Units
Lyophilized powder for injection with 10 mL diluent
Novarel has a findability score of 35 out of 100, meaning it is frequently difficult to locate in stock. Since the FDA reclassified hCG as a biologic product in March 2020, compounding pharmacies have been restricted from producing it, significantly reducing overall supply. Brand-name Novarel and its alternatives like Pregnyl have experienced intermittent shortages, and availability can vary widely by region and pharmacy.
If your local pharmacy is out of stock, Medfinder can help you locate Novarel at pharmacies near you that currently have it available.
Novarel is typically prescribed by specialists, including:
Novarel is not a federally controlled substance. However, some states classify injectable hCG as a Schedule III controlled substance, so regulations may vary by state. Your pharmacist can advise on any state-specific restrictions.
Serious side effects that require immediate medical attention include ovarian hyperstimulation syndrome (OHSS), severe allergic reactions, thromboembolic events (blood clots), ovarian rupture, and sudden vision changes.
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Pregnyl
(Chorionic Gonadotropin) — Another brand of urinary-derived hCG manufactured by Organon. Same active ingredient and indications as Novarel.
Ovidrel
(Choriogonadotropin Alfa) — A recombinant (lab-made) form of hCG available as a pre-filled syringe for subcutaneous injection. More convenient but typically more expensive.
Generic hCG
(Chorionic Gonadotropin) — Generic versions of urinary-derived hCG available from manufacturers like Fresenius Kabi at potentially lower cost.
Prefer Novarel? We can find it.
GnRH antagonists
moderate(e.g., Ganirelix) — Timing of administration must be carefully coordinated in fertility protocols
Menotropins
moderate(e.g., Menopur) — Used in combination but requires careful coordination and monitoring
Pregnancy tests
moderateNovarel contains hCG, which is the hormone pregnancy tests detect, so it can cause false-positive pregnancy test results for up to 10–14 days after injection
Androgens and anabolic steroids
moderateMay have additive androgenic effects when used together
Novarel is a critical medication for fertility treatment and certain hormonal conditions, but ongoing supply challenges have made it difficult to find in stock since the FDA's 2020 reclassification of hCG as a biologic. With a findability score of just 35, patients may need to check multiple pharmacies or explore alternatives like Pregnyl, Ovidrel, or generic hCG.
Important: HCG has NOT been demonstrated to be effective for weight loss. The FDA warns that there is no substantial evidence it increases weight loss beyond caloric restriction alone.
If you're struggling to locate Novarel, Medfinder can help you find pharmacies near you that currently have it in stock. Ask your doctor about Ferring's HeartTomorrow or OneHeart programs for potential savings.
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