Comprehensive medication guide to Lanabiotic including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Estimated Insurance Pricing
Standard health insurance and Medicare Part D do not cover OTC products like Lanabiotic. However, Lanabiotic is FSA and HSA eligible — patients can purchase it with pre-tax dollars, reducing the effective cost by their marginal tax rate.
Estimated Cash Pricing
$5–$15 for a 0.5–1 oz tube at most retail pharmacies and drugstores. Generic equivalents (triple antibiotic + pramoxine) are available for as little as $3–$8 for 1 oz at big-box retailers like Walmart and Target.
Medfinder Findability Score
92/100
On this page
Lanabiotic is a brand-name over-the-counter (OTC) topical ointment that combines two broad-spectrum antibiotics with a topical local anesthetic. It is designed to prevent infection and relieve pain in minor cuts, scrapes, and burns. Lanabiotic does not require a prescription and is available at pharmacies, grocery stores, and online retailers.
Its three active ingredients are Neomycin Sulfate (3.5 mg per gram), an aminoglycoside antibiotic; Polymyxin B Sulfate (10,000 units per gram), a polymyxin antibiotic; and Pramoxine Hydrochloride (10 mg per gram), a topical local anesthetic. Together, they provide broad-spectrum antibacterial coverage and wound-site pain relief.
Lanabiotic is approved for adults and children 2 years and older. It should be applied in a fingertip-sized amount 1–3 times daily to clean wounds. Use should not exceed 7 days unless directed by a doctor.
We have a 99% success rate finding medications, even during nationwide shortages.
Need this medication?
Lanabiotic works through three distinct and complementary mechanisms. Neomycin binds to the 30S ribosomal subunit of bacteria, causing misreading of genetic code and the production of faulty proteins — effectively killing the bacteria from within. Polymyxin B attacks gram-negative bacteria from the outside by disrupting their outer membrane phospholipid layer, causing vital intracellular contents to leak out.
Pramoxine, the anesthetic component, works by blocking sodium ion channels in sensory nerve fibers near the wound. With these channels blocked, pain neurons cannot generate action potentials, resulting in temporary numbness and pain relief. Pain relief typically begins within minutes of application.
The dual-antibiotic approach provides overlapping, multi-target bacterial coverage — making it significantly harder for bacteria to develop resistance to both agents simultaneously. Topical, ophthalmic, and oral formulations of neomycin and polymyxin B are poorly absorbed systemically when used as directed on small wound areas.
Neomycin 3.5 mg / Polymyxin B 10,000 units / Pramoxine 10 mg per gram — topical ointment
Standard OTC formulation; apply fingertip amount 1–3 times daily for up to 7 days
Lanabiotic is not on the FDA's drug shortage list as of 2026 and has not been discontinued or withdrawn for safety or effectiveness reasons. However, as a brand-name OTC product competing with Neosporin in a crowded market, Lanabiotic is not stocked at every pharmacy chain. Store-level stocking decisions drive most availability issues — not a supply chain problem.
Patients most reliably find Lanabiotic at independent pharmacies, specialty medical supply stores, and online retailers including Amazon and Walmart.com. Seasonal demand spikes (summer, back-to-school season) can temporarily deplete local stocks. Generic equivalents (triple antibiotic + pramoxine ointment) are widely available as a substitute at most major retailers.
If you're having trouble finding Lanabiotic at your local pharmacy, medfinder contacts pharmacies near you and texts you which ones have it in stock — no calls needed.
Lanabiotic is an over-the-counter (OTC) product and does not require a prescription. Any adult can purchase it without seeing a healthcare provider. That said, certain clinical situations may lead a provider to specifically recommend Lanabiotic or an equivalent for wound care.
Providers who may recommend Lanabiotic as part of wound care guidance include:
Primary Care Physicians (PCPs) and Family Medicine Doctors
Dermatologists
Emergency Medicine Physicians and Urgent Care Providers
Nurse Practitioners (NPs) and Physician Assistants (PAs)
Pediatricians (for minor wound care in children 2 years and older)
Telehealth providers on platforms such as Teladoc, MDLive, and Amazon Clinic can also evaluate minor wounds and recommend OTC products like Lanabiotic, making access convenient for patients who cannot see a provider in person.
No. Lanabiotic is not a controlled substance and is not scheduled under the DEA Controlled Substances Act. It is an over-the-counter (OTC) product that does not require a prescription from a healthcare provider. Any adult can purchase it directly from a pharmacy, grocery store, or online retailer without any special authorization.
There are no refill restrictions, no quantity limits imposed by law, and no requirement to visit a pharmacy in person versus ordering online. As an OTC product, Lanabiotic can be purchased in any quantity at the buyer's discretion.
Lanabiotic is generally well-tolerated. Common side effects include:
Mild burning or stinging at application site
Local skin irritation or mild itching
Skin dryness around the application area
Serious side effects (rare but important to know):
Allergic contact dermatitis — red, scaly, itchy skin at application site, appearing 24–48 hours after use; most commonly caused by neomycin sensitivity
Ototoxicity (hearing changes) — rare; associated with neomycin systemic absorption from large-area application
Anaphylaxis — extremely rare; stop use and call 911 if you experience difficulty breathing, throat swelling, or rapid heartbeat
Know what you need? Skip the search.
Neosporin + Pain Relief Ointment
Nearly identical OTC formulation adding bacitracin for broader gram-positive coverage; most widely stocked equivalent to Lanabiotic
Generic Triple Antibiotic + Pain Relief
Store-brand equivalents (Equate, Up & Up, Good Sense) with identical active ingredients; typically $3–$8 — best value option
Polysporin
Double antibiotic ointment (bacitracin + polymyxin B); neomycin-free alternative for patients with neomycin allergy; no pain relief component
Bacitracin
Single-antibiotic OTC ointment; lowest allergy risk; appropriate for very minor low-risk wounds; no pain relief component
Mupirocin (Bactroban)
Prescription-only topical antibiotic for established skin infections like impetigo; not for first-aid use on minor wounds
Prefer Lanabiotic? We can find it.
Aminoglycoside antibiotics (gentamicin, tobramycin, amikacin)
moderateAdditive nephrotoxicity and ototoxicity risk when neomycin is systemically absorbed. Clinically relevant only with large-area application; not a concern with standard small-wound topical use.
Loop diuretics (furosemide, ethacrynic acid)
minorMay potentiate ototoxic risk of systemically absorbed neomycin. Not clinically significant with standard topical application to minor wounds.
Neuromuscular blocking agents (vecuronium, succinylcholine)
minorAminoglycosides including neomycin can potentiate neuromuscular blockade. Relevant only in surgical/anesthetic settings, not standard topical OTC use.
Lanabiotic is a safe, effective, and affordable OTC first-aid product that provides both broad-spectrum antibacterial coverage and topical pain relief for minor wounds. Its three-ingredient formula (neomycin, polymyxin B, and pramoxine) offers a meaningful advantage over single-antibiotic or pain-relief-free alternatives for patients who need both infection prevention and symptom relief.
While Lanabiotic is widely available nationally, store-level stocking decisions mean it may not be found at every pharmacy. Generic equivalents labeled 'triple antibiotic + pain relief ointment' (containing neomycin, polymyxin B, and pramoxine HCl) are therapeutically identical and often cheaper and more widely available.
If you're having trouble finding Lanabiotic at your local pharmacy, medfinder can help. We contact pharmacies near you and text you which ones have your medication in stock — no phone calls, no wasted trips.
Medfinder Editorial Standards
Our medication guides are researched and written to help patients make informed decisions. All content is reviewed for accuracy and updated regularly. Learn more about our standards
Real-time availability
Medfinder is actively checking pharmacy inventory for Lanabiotic. We don't publish a number until we have enough verified pharmacy checks to be accurate — start a search and our team confirms current availability near you, usually within 24 hours.
ChatGPT
Claude
Gemini