Comprehensive medication guide to Carvedilol including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Estimated Insurance Pricing
$0–$15/month
Estimated Cash Pricing
$4–$90/month
Medfinder Findability Score
70/100
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Carvedilol is a non-cardioselective beta blocker with additional alpha-1 blocking activity. It is FDA-approved to treat heart failure (NYHA Class II–IV), hypertension (high blood pressure), and left ventricular dysfunction following a heart attack in clinically stable patients.
Originally marketed as Coreg by GlaxoSmithKline, Carvedilol is now available as an affordable generic from manufacturers including Teva, Aurobindo, Zydus, and Sun Pharma. It is also used off-label for atrial fibrillation rate control, portal hypertension in cirrhosis, and angina.
Immediate-release tablets
3.125 mg, 6.25 mg, 12.5 mg, 25 mg
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Extended-release capsules (Coreg CR)
10 mg, 20 mg, 40 mg, 80 mg
Important: Do not stop taking Carvedilol abruptly — sudden discontinuation can cause rebound hypertension, worsening angina, or heart attack. Always taper gradually under your doctor's supervision.
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Metoprolol Succinate (Toprol-XL)
A cardioselective beta-1 blocker, extended-release, FDA-approved for heart failure, hypertension, and angina. The most commonly substituted alternative.
Bisoprolol (Zebeta)
A cardioselective beta-1 blocker approved for hypertension, with strong evidence supporting its use in heart failure (CIBIS-II trial).
Nebivolol (Bystolic)
A third-generation beta-1 selective blocker with nitric oxide-mediated vasodilating properties. Approved for hypertension.
Labetalol (Trandate)
A non-selective beta blocker with alpha-1 blocking activity similar to Carvedilol. Often used for hypertension, especially during pregnancy.
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Calcium channel blockers (Verapamil, Diltiazem)
moderateincreased risk of dangerously slow heart rate and low blood pressure
Digoxin
moderateCarvedilol increases Digoxin levels by approximately 15%
Clonidine
moderaterisk of rebound hypertension if Clonidine is stopped first
CYP2D6 inhibitors (Fluoxetine, Paroxetine, Quinidine)
moderatecan significantly increase Carvedilol blood levels
Insulin and oral diabetes medications
moderateCarvedilol may enhance blood sugar–lowering effects and mask the rapid heartbeat that normally warns of low blood sugar
Rifampin
moderatecan significantly decrease Carvedilol levels, reducing effectiveness
NSAIDs
moderatemay reduce Carvedilol's blood pressure–lowering effect
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