Comprehensive medication guide to Blis-To-Sol Powder including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Estimated Insurance Pricing
Not typically covered by standard insurance as an OTC product. With a doctor's prescription, Medicaid may cover it in some states. Medicare Advantage OTC benefit cards may apply.
Estimated Cash Pricing
$8–$15 per 2 oz bottle OTC retail; $10 direct from manufacturer at oakhurstco.com with multipack discounts available. FSA and HSA eligible.
Medfinder Findability Score
72/100
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Blis-To-Sol Powder is an over-the-counter topical antifungal medication manufactured by Oakhurst Co. Its active ingredient is undecylenic acid (with zinc undecylenate in the powder formulation) — a naturally derived fatty acid with proven antifungal properties. It is classified in the drug class of topical antifungals.
Blis-To-Sol Powder is used to treat and prevent fungal skin infections including athlete's foot (tinea pedis), jock itch (tinea cruris), and ringworm (tinea corporis). It is available without a prescription (OTC) and comes in a 2 oz powder bottle. No DEA scheduling applies — it is not a controlled substance.
Note: Oakhurst Co. also makes Blis-To-Sol Liquid, which contains tolnaftate 1% (a different active ingredient). The Powder and Liquid formulations are distinct products. This listing covers the Powder formulation containing undecylenic acid.
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Undecylenic acid is a C11 fatty acid that works as a fungistatic agent — it prevents fungal cells from growing and reproducing rather than directly killing them. It disrupts the fatty acid environment that fungi (dermatophytes like Trichophyton and Epidermophyton) require to survive and replicate on the skin surface.
Specifically, undecylenic acid inhibits the morphological switching of Candida from yeast to invasive hyphal (thread-like) form, partially disrupts fungal cell membrane integrity, and alters the local fatty acid environment to be hostile to fungal growth. Zinc undecylenate in the powder formulation provides additional antifungal activity and helps dry and soothe the skin.
The powder formulation offers an additional advantage: it absorbs moisture from the skin surface and can be applied inside socks and shoes to eliminate the warm, moist environment that promotes fungal growth. A Cochrane Database meta-analysis of 72 trials found undecylenic acid achieved a 72% cure rate for athlete's foot — the highest among OTC antifungal options studied.
Undecylenic acid topical powder — Powder
2 oz bottle. Apply twice daily to affected area and surrounding skin. Apply between toes, on feet, and inside socks and shoes for athlete's foot.
Undecylenic acid topical powder — Aerosol Powder
Spray form available. Shake before use. Apply from 6-10 inches away. Do not inhale. Do not use near open flame.
Blis-To-Sol Powder has a findability score of 72/100. While it is not in an FDA-designated shortage, it has limited retail distribution that makes it harder to find than major national OTC antifungal brands like Tinactin (tolnaftate) or Lamisil AT (terbinafine). Blis-To-Sol is made by a smaller regional manufacturer (Oakhurst Co.) and is not consistently stocked at CVS, Walgreens, or Rite Aid in most markets.
The most reliable sources are oakhurstco.com (direct from the manufacturer at $10/bottle) and Amazon (with Prime 1-2 day shipping). Independent pharmacies are also more likely to carry or be able to order it. Availability can vary by region and season, with summer demand spikes sometimes causing temporary stock-outs at stores that do carry it.
To find Blis-To-Sol Powder at a pharmacy near you without calling stores yourself, use medfinder. medfinder calls pharmacies in your area to check which ones have it in stock and texts you the results.
Blis-To-Sol Powder is an OTC product — no prescription is required. Any licensed healthcare provider can recommend it, and patients can purchase it directly without a healthcare visit. Because it is not a controlled substance and has no special prescribing requirements, the following providers routinely recommend or oversee its use:
Primary care physicians (PCPs) and family medicine doctors
Dermatologists — for complex or refractory fungal skin infections
Podiatrists — especially for athlete's foot with nail involvement
Nurse practitioners (NPs) and physician assistants (PAs)
Pharmacists — can recommend it directly to patients as an OTC antifungal
Telehealth is available for guidance on OTC antifungal use. Providers on telehealth platforms can evaluate mild-to-moderate fungal infections via video and recommend Blis-To-Sol Powder or appropriate prescription alternatives if needed — without an in-person visit.
No. Blis-To-Sol Powder is not a controlled substance. It has no DEA schedule (CSA Schedule: N/A) and is classified as an over-the-counter medication that can be purchased without a prescription. There are no special prescribing requirements, refill restrictions, or state-level controlled substance regulations that apply to this product.
As an OTC topical antifungal, Blis-To-Sol Powder can be recommended by any licensed healthcare provider — or purchased by patients directly without any healthcare visit. Pharmacists can also recommend it over the counter. There are no monitoring requirements, prior authorization processes, or quantity limits associated with controlled substance status for this product.
Blis-To-Sol Powder is generally well-tolerated. Common mild side effects include:
Mild skin irritation at application site
Itching or redness at the treated area
Dryness or peeling of treated skin
Mild burning sensation on application
Allergic reaction: Hives, difficulty breathing, swelling of the face, lips, tongue, or throat — call 911 immediately
Worsening skin irritation: Significant new or worsening redness, blistering, or pain not present before use — stop product and contact your doctor
No improvement after 4 weeks: Consult your healthcare provider if the infection does not improve after 4 weeks of consistent twice-daily use
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Terbinafine (Lamisil AT)
OTC allylamine antifungal; fungicidal; 70% cure rate for tinea pedis; widely stocked at all major pharmacies; available as cream, gel, spray, powder. Fastest resolution among OTC options.
Tolnaftate (Tinactin)
OTC thiocarbamate antifungal; fungistatic; 64% cure rate; available as powder, cream, spray — closest substitute in powder form to Blis-To-Sol Powder. Widely available.
Clotrimazole (Lotrimin AF)
OTC azole antifungal; broad spectrum including Candida; 47% cure rate for tinea pedis; cream form; suitable for mixed or sensitive skin infections.
Miconazole (Desenex, Zeasorb-AF)
OTC azole antifungal; available as powder and cream; good moisture control; useful for athlete's foot with significant moisture issues.
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Other topical antifungals
minorAvoid applying multiple topical antifungals to the same skin area simultaneously. Not proven to be more effective and may increase skin irritation.
Topical corticosteroids
moderateUsing topical steroids like hydrocortisone on the same area without antifungal coverage can promote fungal growth. Use combination products only under medical guidance.
Oral or injectable medications (general)
minorNo significant systemic interactions known. Topical undecylenic acid has minimal systemic absorption and does not affect hepatic enzyme metabolism or drug levels.
Blis-To-Sol Powder is a well-established, clinically supported OTC antifungal powder that outperformed other OTC options in a major Cochrane meta-analysis with a 72% cure rate for athlete's foot. Its undecylenic acid and zinc undecylenate formulation provides both antifungal activity and moisture absorption — a practical advantage over creams and liquids for foot fungal infections.
The main challenge with Blis-To-Sol Powder in 2026 is availability: it has limited retail distribution and is not consistently stocked at major pharmacy chains. Patients can reliably obtain it from oakhurstco.com ($10 direct), Amazon, or independent pharmacies. For patients who need it locally and urgently, medfinder can identify which nearby pharmacies have it in stock without requiring patients to call around themselves.
If you're struggling to find Blis-To-Sol Powder near you, medfinder can help. medfinder calls pharmacies on your behalf, checks which ones have your medication in stock, and texts you the results — saving you time and frustration.
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Our medication guides are researched and written to help patients make informed decisions. All content is reviewed for accuracy and updated regularly. Learn more about our standards
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