What Is Blis-To-Sol Powder? Uses, Dosage, and What You Need to Know in 2026

Blis-To-Sol Powder is an over-the-counter antifungal medication used to treat fungal infections of the skin. It's been around for decades and remains a trusted option for treating conditions like athlete's foot, jock itch, and ringworm. Here's a complete guide to what it is, how to use it, and what you need to know in 2026.

What Is Blis-To-Sol Powder?

Blis-To-Sol Powder is a topical antifungal powder made by Oakhurst Co. Its active ingredient is undecylenic acid (with zinc undecylenate in the powder formulation). Undecylenic acid is a naturally derived fatty acid with antifungal properties — it works by disrupting the conditions that allow fungal cells to grow and spread.

The product is available without a prescription (OTC), comes in a 2 oz powder bottle, and is classified in the drug class of topical antifungals.

What Is Blis-To-Sol Powder Used For?

Blis-To-Sol Powder is approved for treating and preventing these skin fungal infections:

Athlete's foot (tinea pedis): A fungal infection affecting the skin of the feet, especially between the toes. Causes itching, burning, cracking, and peeling.

Jock itch (tinea cruris): A fungal infection of the groin, inner thighs, and buttocks. Causes itching, redness, and a ring-shaped rash.

Ringworm (tinea corporis): A fungal infection of the skin on the body (not a worm). Creates a circular, scaly rash.

Preventive use: After completing treatment, the powder can be used daily after bathing to prevent athlete's foot from returning in people prone to recurrence.

Blis-To-Sol Powder may also be used alongside prescription oral antifungals to help treat more stubborn nail or scalp fungal infections, though it is not effective as a standalone treatment for nail fungus (onychomycosis).

How Effective Is Blis-To-Sol Powder?

Undecylenic acid has strong clinical evidence behind it. A meta-analysis published in the Cochrane Database of Systematic Reviews, covering 72 placebo-controlled trials, found undecylenic acid achieved a 72% clinical cure rate for athlete's foot — the highest among OTC antifungal ingredients studied, including terbinafine (70%), tolnaftate (64%), and azoles like clotrimazole (47%).

Dosage: How to Use Blis-To-Sol Powder Correctly

Follow these steps for safe and effective use:

Wash the affected area with soap and water, then dry thoroughly — especially between the toes

Apply the powder to the affected area and surrounding skin twice daily (morning and evening)

For athlete's foot: Apply between toes, on the soles of both feet, and inside your socks and shoes

Duration: Treat for 2-4 weeks; continue for 2 weeks after symptoms disappear to prevent recurrence

Wash hands before and after application unless treating hand skin

Children 2 years and older may use the product with adult supervision. Do not use on children under 2 without medical advice.

Is Blis-To-Sol Powder a Controlled Substance?

No. Blis-To-Sol Powder is not a controlled substance. It has no DEA scheduling and is available OTC without a prescription at pharmacies, online retailers, and directly from the manufacturer at oakhurstco.com.

How Does Blis-To-Sol Powder Differ From the Blis-To-Sol Liquid?

It's important to note that Oakhurst Co. makes two different Blis-To-Sol products with different active ingredients:

Blis-To-Sol Powder: Active ingredient is undecylenic acid (with zinc undecylenate) — a fatty acid antifungal

Blis-To-Sol Liquid: Active ingredient is tolnaftate 1% — a thiocarbamate antifungal. Different chemistry, same general indications.

Both products treat athlete's foot, jock itch, and ringworm, but with different active ingredients. When searching for or discussing Blis-To-Sol Powder specifically, make sure you and your pharmacist are on the same page about which formulation you need.

Where to Find Blis-To-Sol Powder

Blis-To-Sol Powder has limited retail distribution. Your best options are oakhurstco.com ($10/bottle), Amazon, or independent pharmacies. If you need to find it at a local pharmacy quickly, medfinder can call pharmacies near you and text you which ones have it in stock.

Want to understand more about how it works? See our guide: How Does Blis-To-Sol Powder Work? Mechanism of Action Explained.