Comprehensive medication guide to Abilify including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Estimated Insurance Pricing
With insurance, generic Aripiprazole is typically a Tier 2 copay of $10–$30 per month, though brand-name Abilify may require prior authorization.
Estimated Cash Pricing
Generic Aripiprazole costs $10–$50 per month with a discount card, while brand-name Abilify runs $800–$1,200 per month without insurance.
Medfinder Findability Score
65/100
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Abilify (Aripiprazole) is an atypical antipsychotic medication manufactured by Otsuka Pharmaceutical and Bristol-Myers Squibb. It is FDA-approved to treat a range of mental health conditions, including:
Abilify is also used off-label for conditions like obsessive-compulsive disorder (augmentation), PTSD, generalized anxiety disorder, and treatment-resistant depression. It is taken once daily, with or without food, and is available in multiple formulations including tablets, orally disintegrating tablets, oral solution, and long-acting injectable forms.
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Abilify works differently from many other antipsychotics. It is classified as a partial agonist at dopamine D2 and D3 receptors and serotonin 5-HT1A receptors, and an antagonist at serotonin 5-HT2A receptors. This unique mechanism is sometimes described as a "dopamine stabilizer" — when dopamine activity in the brain is too high, Abilify helps bring it down, and when dopamine activity is too low, it helps boost it. This balanced approach is why Abilify tends to have a different side effect profile compared to older antipsychotics, with generally less sedation and lower risk of prolactin elevation.
Oral Tablets
2 mg, 5 mg, 10 mg, 15 mg, 20 mg, 30 mg
Oral Solution — solution
1 mg/mL
Short-Acting Intramuscular Injection — injection
9.75 mg/1.3 mL
Abilify Maintena (Extended-Release Injectable)
300 mg, 400 mg (monthly)
Abilify Asimtufii (Extended-Release Injectable)
720 mg, 960 mg (every 2 months)
Abilify (Aripiprazole) receives a findability score of 65 out of 100, placing it in the moderate range. Generic Aripiprazole tablets are widely manufactured and stocked at most pharmacies across the country, with availability further improving since the FDA approved 4 additional generic manufacturers in December 2025, increasing competition and supply options. The oral form is generally not difficult to find. However, the long-acting injectable formulations — Abilify Maintena and Abilify Asimtufii — have experienced intermittent supply constraints due to manufacturing capacity issues in 2023–2024, which occasionally persist into 2026. Some patients also report sporadic difficulty finding specific generic manufacturer tablets at their local pharmacy. If you're having trouble locating your specific dose or formulation, Medfinder can help you search nearby pharmacies with current stock.
Abilify is most commonly prescribed by psychiatrists and child and adolescent psychiatrists, given its primary use in serious mental health conditions. However, it is also frequently prescribed by:
Abilify is also available through telehealth platforms, making it accessible for patients who may not have easy access to a specialist.
No, Abilify (Aripiprazole) is not a controlled substance. It does not have a DEA schedule classification, which means it does not carry the same prescribing restrictions as medications like benzodiazepines or stimulants. Your doctor can prescribe it with standard refills, and pharmacies can dispense it without the additional regulatory requirements that apply to scheduled drugs.
Like all medications, Abilify can cause side effects. The most commonly reported include:
Serious side effects to watch for include neuroleptic malignant syndrome (NMS), tardive dyskinesia, hyperglycemia and diabetes, impulse control problems (such as pathological gambling, compulsive eating, or hypersexuality), and orthostatic hypotension. Abilify carries two boxed warnings: increased mortality in elderly patients with dementia-related psychosis, and increased risk of suicidal thinking in children, adolescents, and young adults. Contact your doctor immediately if you experience any serious side effects.
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Brexpiprazole (Rexulti)
A close relative of Abilify with a similar dopamine partial agonist mechanism. Used for schizophrenia and adjunctive MDD treatment, and may cause less akathisia (restlessness) than Abilify.
Risperidone (Risperdal)
Used for schizophrenia, bipolar mania, and irritability in autism. It may cause more weight gain and prolactin elevation than Abilify.
Quetiapine (Seroquel)
Used for schizophrenia, bipolar disorder, and adjunctive MDD. More sedating and carries higher metabolic side effect risk.
Ziprasidone (Geodon)
Has a lower weight gain risk but requires twice-daily dosing with food and carries a risk of QTc prolongation.
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Strong CYP3A4 inhibitors
moderate(Ketoconazole, Itraconazole, Clarithromycin) — These increase Abilify levels in the blood, and your doctor may need to reduce your dose.
Strong CYP2D6 inhibitors
moderate(Fluoxetine, Paroxetine, Quinidine) — Also increase Abilify levels; dose reduction may be needed.
Strong CYP3A4 inducers
moderate(Carbamazepine, Rifampin, St. John's Wort) — These decrease Abilify levels, potentially requiring a dose increase.
CNS depressants
moderate(Benzodiazepines, opioids) — Additive sedation risk.
Antihypertensive medications
moderateMay cause additive blood pressure lowering.
Lithium
moderateMonitor for neurotoxicity when used together.
Abilify (Aripiprazole) is one of the most widely prescribed atypical antipsychotics in the United States, valued for its unique dopamine-stabilizing mechanism and broad range of approved uses. Generic Aripiprazole is affordable — as low as $10–$50 per month with a discount card — making it accessible for most patients.
Important update (2026): Otsuka has discontinued Abilify Discmelt oral disintegrating tablets. If you were using this formulation, work with your prescriber to transition to regular tablets, oral solution, or alternative ODT options.
While the oral formulation is generally easy to find, patients using long-acting injectable forms like Abilify Maintena may occasionally face supply challenges. If you're having difficulty locating Abilify at your local pharmacy, Medfinder can help you search pharmacies near you with current availability. Talk to your doctor about whether Abilify is right for your treatment plan, and never stop taking it abruptly without medical guidance.
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