What Is Vanacof AC? Uses, Dosage, and What You Need to Know in 2026

Vanacof AC is an over-the-counter oral liquid used to relieve cough and allergy symptoms caused by the common cold, hay fever, and other upper respiratory conditions. It combines two active ingredients — a non-narcotic cough suppressant and an antihistamine — to address multiple symptoms at once without containing a decongestant. Here's everything you need to know about Vanacof AC in 2026.

What Is Vanacof AC?

Vanacof AC is a brand-name OTC (over-the-counter) cough and allergy syrup manufactured by GM Pharmaceuticals, Inc. It is formulated as an oral liquid in a 30 mL dose. The "AC" in the name stands for "Antihistamine-Cough" — reflecting its two-component formula. It is:

Alcohol-free

Decongestant-free (no pseudoephedrine or phenylephrine)

Not a controlled substance

Available over the counter (no prescription required)

What Are the Active Ingredients?

Each 30 mL dose of Vanacof AC contains:

Chlophedianol HCl 12.5 mg — a non-narcotic cough suppressant. Works in the brain to reduce the urge to cough.

Pyrilamine Maleate 25 mg — a first-generation antihistamine. Blocks histamine receptors to reduce runny nose, sneezing, and itchy, watery eyes.

What Is Vanacof AC Used For?

Vanacof AC temporarily relieves the following symptoms:

Cough due to minor throat and bronchial irritation (common cold or inhaled irritants)

Runny nose

Sneezing

Itchy, watery eyes

Itching of the nose or throat

These symptoms may be caused by the common cold, hay fever (allergic rhinitis), or other upper respiratory allergies. Vanacof AC is intended for temporary, short-term symptom relief only.

Vanacof AC Dosage: How Much Should You Take?

Follow the directions on the product label or those provided by your healthcare provider. Standard dosing for Vanacof AC:

Adults and children 12 and older: 30 mL every 6 hours as needed (approximately 1 fl oz or 2 tablespoons)

Maximum daily dose: Do not exceed 4 doses (120 mL) in any 24-hour period

Children under 6: Do not use unless specifically directed by a physician

Always use the measuring device provided with the product — do not estimate using household spoons. Taking too much can increase the risk of side effects, including drowsiness, dizziness, and in severe overdose, hallucinations or seizures.

Who Should NOT Take Vanacof AC?

Do not take Vanacof AC if you have:

A chronic cough due to smoking, asthma, or emphysema

A cough with excessive phlegm (mucus)

Glaucoma

Difficulty urinating due to prostate enlargement

A breathing problem such as emphysema or chronic bronchitis

Used an MAOI (monoamine oxidase inhibitor) within the past 14 days

Important: When to Stop Taking Vanacof AC

Stop using Vanacof AC and contact your doctor if:

Symptoms don't improve within 7 days

Symptoms tend to recur (a recurring cough can be a sign of a serious condition)

Symptoms are accompanied by a fever, rash, or persistent headache

For a detailed guide on side effects, see: Vanacof AC Side Effects: What to Expect and When to Call Your Doctor. Can't find Vanacof AC at your pharmacy? medfinder can locate it for you.