What Is Lidopro Patch?

Lidopro Patch is a prescription topical hydrogel patch that delivers three pain-fighting ingredients — Lidocaine, Menthol, and Methyl Salicylate — directly through the skin to relieve muscle and joint pain.

Made by Terrain Pharmaceuticals (TerrainRx) in Reno, Nevada, Lidopro Patch uses patented hydrogel transdermal delivery technology with micro-emulsifiers that help the active ingredients absorb deeper and faster into muscles, joints, tendons, and nerves.

Key Facts at a Glance

• Brand name: Lidopro Patch
• Generic name: Lidocaine/Menthol/Methyl Salicylate Topical Patch
• Drug class: Topical analgesic/anesthetic/anti-inflammatory combination
• Manufacturer: Terrain Pharmaceuticals, Inc.
• Controlled substance: No
• Generic available: No direct generic equivalent

What Is Lidopro Patch Used For?

Lidopro Patch is prescribed for the temporary relief of minor aches and pains of muscles and joints. Specific conditions include:

• Arthritis pain — Joint pain and stiffness from osteoarthritis or rheumatoid arthritis
• Back pain — Lower back, mid-back, and upper back pain
• Muscle strains and sprains — From sports injuries, overexertion, or accidents
• Joint pain — Knees, elbows, shoulders, and other joints
• Shoulder pain — Including rotator cuff and tension-related pain
• Knee pain — From injury, arthritis, or overuse

Some doctors also prescribe Lidopro Patch off-label for neuropathic pain, migraine-related neck pain, post-surgical pain management, and fibromyalgia-related pain.

To understand how the ingredients work together, see our article on how Lidopro Patch works.

How Is Lidopro Patch Used?

Using Lidopro Patch is straightforward:

1. Clean and dry the affected area.
2. Open the sealed pouch and remove the patch.
3. Peel off the protective liner to expose the medicated side.
4. Apply directly to the skin over the painful area.
5. Press firmly to ensure good contact.
6. Optional: Use the outer adhesive layer for extra security on areas like the lower back, knees, elbows, and shoulders.
7. Wear for up to 12 hours, then remove.
8. Wait at least 12 hours before applying a new patch.
9. Wash your hands after application.

Important Dosage Rules

• Use no more than 1 patch at a time.
• Do not apply to open wounds, cuts, or damaged skin.
• Do not use with a bandage, heating pad, hot tub, or sauna.
• Do not apply to raw or blistered skin.

Who Should Not Use Lidopro Patch?

Do not use Lidopro Patch if you:

• Are allergic to any of the ingredients, PABA, aspirin products, or sulfa drugs
• Have open wounds, cuts, or damaged skin at the application site
• Take Warfarin (Coumadin) — the Methyl Salicylate can increase bleeding risk

Talk to your doctor before use if you are pregnant, breastfeeding, or planning to use it on a child. For a complete list of interactions, see our drug interactions guide.

How Much Does Lidopro Patch Cost?

Without insurance, Lidopro Patch typically costs between $150 and $350 per box, depending on the pharmacy and quantity.

Insurance coverage varies. Some plans cover it, but others may require prior authorization or step therapy with OTC alternatives first. Because Lidopro Patch is distributed through independent pharmacies and physician-dispensing networks, not all insurance plans have it on their formulary.

There is no direct generic equivalent for Lidopro Patch. However, generic Lidocaine patches (4% OTC or 5% Rx) are available for $15 to $80, though they contain only one of the three active ingredients.

For help reducing your cost, check out our guide on how to save money on Lidopro Patch.

Side Effects

Common side effects include mild skin irritation, redness, itching, and a cooling or tingling sensation at the application site. Serious side effects are rare but can include severe skin reactions or allergic responses. Read our full breakdown of Lidopro Patch side effects.

Final Thoughts

Lidopro Patch is a multi-ingredient topical pain patch that offers an alternative to oral painkillers for muscle and joint pain. It combines Lidocaine, Menthol, and Methyl Salicylate in a hydrogel patch designed for deeper absorption. While it's not available everywhere, it can be a helpful option for people with arthritis, back pain, sprains, and other musculoskeletal conditions.

If you have a prescription and need help finding it, Medfinder can show you which pharmacies near you have Lidopro Patch in stock.