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Updated: March 1, 2026

What Is Integra F? Uses, Dosage, and What You Need to Know in 2026

Author

Peter Daggett

Peter Daggett

What is Integra F drug guide illustration

Integra F is a prescription iron supplement with folic acid used to treat iron deficiency anemia. Here's everything you need to know about what it is, how to take it, and who it's for.

If your doctor just prescribed Integra F and you want to know more about it before filling your prescription, this is the guide for you. Here's everything patients need to know about Integra F — what's in it, what it treats, how to take it, and what to watch for.

What Is Integra F?

Integra F is a brand-name prescription supplement manufactured by U.S. Pharmaceutical Corporation. It is classified as an iron product combined with vitamins and minerals. Each maroon capsule contains:

  • 125 mg elemental iron (from 191.1 mg Ferrous Fumarate + 135.9 mg Polysaccharide Iron Complex)
  • 1 mg Folic Acid (the standard therapeutic dose for anemia treatment)
  • 40 mg Ascorbic Acid (Vitamin C) (from ProAscorb C — helps enhance iron absorption)
  • 3 mg Niacin (Vitamin B3) (from ProAscorb C)

It is labeled as "Rx only" (prescription required) and is made in maroon Vcaps capsules imprinted with "Integra F" and the "US" logo. It comes in 30-capsule and 90-capsule bottles.

What Is Integra F Used For?

Integra F has three labeled indications:

  1. Iron deficiency anemia — treating anemia caused by insufficient iron (from poor intake, excessive loss, or increased need)
  2. Folate deficiency anemia — treating anemia caused by insufficient folic acid (Vitamin B9)
  3. Pregnancy support — prevention and treatment of iron deficiency in pregnancy, plus maintenance of folic acid levels

Integra F is particularly valued in cases where patients need a high-dose iron supplement but have had difficulty tolerating the GI side effects of standard ferrous sulfate.

How Do You Take Integra F?

Standard dosing per the prescribing information:

  • Dose: One capsule daily
  • Timing: Between meals, or as directed by your physician
  • Age: Adults and persons over 12 years of age
  • Storage: Room temperature 59–86°F (15–30°C), dry place, away from children

Do not take more than one capsule per day unless specifically directed by your doctor. Do not open, crush, or chew the capsule — swallow it whole with a full glass of water.

Who Should NOT Take Integra F?

Do not take Integra F if you have:

  • Hemosiderosis or hemochromatosis (iron overload disorders)
  • Hemolytic anemia (red blood cells broken down too quickly)
  • Pernicious anemia (B12 deficiency anemia) — folic acid can mask its symptoms
  • Known allergy to any of the ingredients
  • Children under 12 years of age

Integra F vs. Other Iron Supplements: Key Differences

What sets Integra F apart from standard iron supplements is its dual-iron delivery system. Most iron supplements use a single source of iron (ferrous sulfate, ferrous gluconate, or carbonyl iron). Integra F uses both Ferrous Fumarate and Polysaccharide Iron Complex together — providing two pathways for iron absorption and reducing the concentration of any single iron form in the gut, which is thought to improve tolerability.

Additionally, the 1 mg folic acid in each capsule is a full therapeutic dose — not a trace amount. This is especially important during pregnancy, when folic acid is critical for fetal neural tube development.

How to Get Integra F

You need a prescription from a licensed healthcare provider. Once you have your prescription, use medfinder to find a pharmacy near you that has Integra F in stock. Because it's a specialty brand-only supplement, not all pharmacies carry it — checking multiple pharmacies is often necessary.

Frequently Asked Questions

Integra F is indicated for the treatment of iron deficiency anemia, folate deficiency anemia, and prevention/treatment of iron deficiency during pregnancy. It provides 125 mg of elemental iron and 1 mg of folic acid per capsule.

Most patients with iron deficiency anemia see measurable improvement in hemoglobin levels within 2–4 weeks of starting iron therapy, with symptoms (fatigue, weakness) often improving in the first 1–2 weeks. Full iron store replenishment (ferritin normalization) typically takes 3–6 months of consistent use.

Yes. Integra F is specifically indicated in pregnancy for the prevention and treatment of iron deficiency and to supply a maintenance dose of folic acid. Consult your OB/GYN about the appropriate dose and duration during pregnancy. Your provider should also rule out pernicious anemia before prescribing for megaloblastic anemia in pregnancy, as folic acid can mask B12 deficiency signs.

Integra F provides a much higher therapeutic dose of iron (125 mg elemental iron) than typical prenatal vitamins (which contain 27 mg). Prenatal vitamins are designed for nutritional support during healthy pregnancies, while Integra F is a therapeutic supplement for established iron deficiency anemia. Many pregnant women with diagnosed iron deficiency take Integra F in addition to or instead of a standard prenatal vitamin.

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