What Is Incassia 28 Day? Uses, Dosage, and What You Need to Know in 2026

Incassia 28 Day is a prescription birth control pill containing norethindrone 0.35 mg — a progestin-only oral contraceptive (also called the "mini-pill" or POP). It is manufactured by Aurobindo Pharma and available in blister packs of 28 tablets, all of which are active (there are no placebo pills in the pack).

What Is Incassia 28 Day Used For?

Incassia's primary FDA-approved use is prevention of pregnancy. It is a progestin-only contraceptive, which means it contains no estrogen — making it an important option for patients who cannot use estrogen-containing contraceptives.

Norethindrone 0.35 mg (the active ingredient in Incassia) is also sometimes prescribed off-label for:

Menstrual disorders and irregular bleeding caused by hormonal imbalance

Endometriosis (off-label, typically at higher doses and using a different formulation)

Abnormal uterine bleeding (the 28-day contraceptive formulation is sometimes used for this purpose)

Who Is Incassia 28 Day Best For?

Incassia is a particularly good fit for:

Patients who cannot take estrogen (smokers over 35, those with migraines with aura, history of blood clots, hypertension, or cardiovascular disease)

Breastfeeding individuals (progestin-only pills do not suppress milk production the way estrogen-containing pills can)

Those who want a daily oral contraceptive without estrogen's associated risks

Patients who have had side effects with estrogen-containing pills

How Effective Is Incassia 28 Day?

When taken with perfect use — one pill every day at the exact same time — the first-year failure rate is 0.5%, meaning fewer than 1 in 200 women become pregnant over a year of perfect use. With typical use (accounting for missed or late doses), the failure rate rises to approximately 5%, or about 5 pregnancies per 100 women per year.

This is slightly less effective than combination birth control pills, largely because the 3-hour missed-dose window for norethindrone is much stricter. Consistency is critical.

How to Take Incassia 28 Day Correctly

Take one tablet every day — at the same time each day, no more than 24 hours apart. Set a phone alarm if needed.

No break between packs — start a new pack the day after finishing the last one. All 28 pills are active.

The 3-hour rule — If you take your pill more than 3 hours late, use backup contraception (condoms, spermicide) for the next 48 hours. This is the most important rule for norethindrone mini-pill users.

Take with food if needed — Can be taken with or without food. If nausea is a problem, take it at bedtime or with a meal.

Vomiting and diarrhea — These can reduce absorption. Use backup contraception for 48 hours if you vomit within a few hours of taking your pill.

When Does Incassia Start Working?

If you start taking Incassia on the first day of your menstrual period (Day 1 Start), it becomes effective immediately — no backup contraception needed. If you start on any other day, use backup contraception for the first 48 hours.

Is Incassia a Controlled Substance?

No. Incassia 28 Day is not a controlled substance and is not scheduled by the DEA. It requires a prescription in the US, but there are no refill limits, no special DEA licensing requirements for prescribers, and no restrictions on early refills based on controlled substance schedules.

What Are Other Brand Names for Norethindrone 0.35 mg?

Incassia is one of many brand names for the same generic drug: norethindrone 0.35 mg. Other brands include Camila, Errin, Heather, Jencycla, Nora-Be, Sharobel, Lyza, Lyleq, Deblitane, and Jolivette. They are all FDA-equivalent and can be substituted for each other in most cases.

Curious how it actually works inside your body? Read: How Does Incassia 28 Day Work? Mechanism of Action Explained.

Need help finding Incassia in stock near you? medfinder calls pharmacies near you to find which ones have your medication.