What Is Florical? Uses, Dosage, and What You Need to Know in 2026

Florical is a brand-name dietary supplement that combines sodium fluoride and calcium carbonate in a single capsule. Manufactured by Mericon Industries of Peoria, Illinois, it has been used for decades in both bone health management and the medical treatment of otosclerosis — a condition that causes progressive hearing loss due to abnormal bone remodeling in the inner ear.

Despite being a supplement rather than an FDA-approved drug, Florical plays a significant clinical role — it's the only widely available OTC combination of sodium fluoride and calcium in this formulation. Here's everything you need to know about it in 2026.

What Is Florical?

Florical is an oral capsule supplement with the following active ingredients per capsule:

• Fluoride: 3.75 mg (delivered as 8.3 mg sodium fluoride)
• Calcium: 145 mg (delivered as 364 mg calcium carbonate from oyster shell)

Inactive ingredients include microcrystalline cellulose, magnesium stearate, and a gelatin capsule shell. It is available in 100-capsule and 500-capsule bottles, sold over the counter.

What Is Florical Used For?

Florical has several established uses:

1. Otosclerosis management — This is the most medically significant use of Florical. Otosclerosis (also called otospongiosis) is a condition where abnormal bone grows in the middle and inner ear, causing progressive conductive and sensorineural hearing loss. Sodium fluoride has been used since the 1960s to slow this abnormal bone remodeling process. Florical provides sodium fluoride with calcium in a convenient OTC formulation.
2. Osteoporosis prevention and management — Florical provides both fluoride, which stimulates bone formation, and calcium, which is essential for maintaining bone mineral density. It can be used as part of a comprehensive osteoporosis prevention strategy alongside vitamin D and lifestyle modifications.
3. Dental strength and gum health — Fluoride is well known for its role in dental enamel protection. The fluoride in Florical can contribute to overall dental strength.
4. Tinnitus associated with otosclerosis — A 2024 study of 128 patients found that Florical may reduce tinnitus severity in patients with mild-to-moderate otosclerosis-related tinnitus.

How Do You Take Florical?

The dosage of Florical depends on your condition and your provider's guidance:

• General bone health / maintenance: 1 capsule once daily with meals
• Active otosclerosis treatment: Often prescribed at 2 capsules three times daily (TID) with meals for 2 years, then reduced to 1 capsule once daily for maintenance

Always take Florical with meals to minimize the risk of stomach upset, which is the most commonly reported side effect. Take it with a full glass of water.

Is Florical a Prescription Drug?

No. Florical is an over-the-counter dietary supplement. You do not need a prescription to purchase it. It is classified as a dietary supplement in accordance with DSHEA (the Dietary Supplement Health and Education Act), not as an FDA-approved drug. This means:

• It has not gone through the FDA drug approval process
• It is not covered by most insurance plans
• It is not subject to prescription drug shortages
• It is not a controlled substance

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What Are the Side Effects?

Common side effects include stomach upset, nausea, allergic itching, and — in some patients — increased joint pain (particularly in those with pre-existing arthritis). Taking it with food significantly reduces GI side effects.

Stop taking Florical and contact your doctor if you develop significant joint pain worsening, signs of allergic reaction (rash, swelling, difficulty breathing), or persistent severe stomach pain.

What Is Otosclerosis and Why Does Florical Help?

Otosclerosis is an abnormal growth of bone in the otic capsule of the inner ear. In the most common form, this abnormal bone immobilizes the stapes (a tiny bone in the middle ear), causing conductive hearing loss. In cochlear otosclerosis, the inner ear is affected, causing sensorineural hearing loss.

Sodium fluoride is thought to slow this process by reducing the enzyme activity responsible for bone resorption in the diseased area, promoting more normal bone mineralization. There are no FDA-approved drugs specifically for otosclerosis, making Florical's sodium fluoride content one of the few available medical interventions.

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Where Can You Get Florical?

Florical is available at some pharmacies and widely available online through Amazon, Walgreens.com, Target, and the manufacturer's website (mericonindustries.com). If you're having trouble finding it locally, medfinder contacts pharmacies near you to check stock and texts you results.

To understand how Florical works at a biological level, see: How Does Florical Work? Mechanism of Action Explained in Plain English