Ertaczo (Sertaconazole Nitrate) is a prescription antifungal cream for athlete's foot. Learn about its uses, dosage, cost, side effects, and what to know in 2026.
Ertaczo (Sertaconazole Nitrate 2% cream) is a prescription topical antifungal medication used to treat interdigital tinea pedis — the form of athlete's foot that occurs between the toes. It was approved by the FDA and is manufactured by DPT Laboratories and distributed by Coral Way Pharma, LLC. The Ertaczo trademark is owned by Lacer Pharma, LLC.
If your doctor has prescribed Ertaczo or you're wondering whether it might be right for you, this guide covers everything you need to know — from what it treats and how to use it, to what it costs and where to find it.
Here are the key facts about Ertaczo:
Ertaczo belongs to the imidazole class of antifungal medications, the same family as Clotrimazole (Lotrimin) and Ketoconazole. However, Ertaczo has a unique dual mechanism of action that sets it apart. Learn more about how Ertaczo works.
Ertaczo is FDA-approved for the topical treatment of interdigital tinea pedis (athlete's foot between the toes) in immunocompetent patients 12 years of age and older. It is effective against the following fungi:
While Ertaczo is only FDA-approved for interdigital tinea pedis, doctors sometimes prescribe it off-label for other fungal skin infections, including:
Off-label use means the medication is being used in a way not specifically approved by the FDA, but your doctor may recommend it based on clinical evidence and their medical judgment.
Using Ertaczo correctly is important for getting the best results. Here's how to apply it:
Ertaczo has no specific contraindications listed in its prescribing information, but certain people should use caution or discuss with their doctor first:
For more information on side effects, read our detailed guide on Ertaczo side effects.
Ertaczo is a brand-name medication with no generic alternative, which makes it one of the more expensive topical antifungals on the market.
For a complete breakdown of savings options, see our guide on how to save money on Ertaczo.
Ertaczo's high price is largely due to its brand-only status. Without generic competition, there's no downward price pressure. Many patients and doctors explore alternative antifungal treatments when cost is a barrier.
Because Ertaczo is a brand-only product with limited demand, not every pharmacy keeps it in stock. If your pharmacy doesn't have it:
How does Ertaczo stack up against other antifungal treatments?
Ertaczo's main advantage is its dual mechanism of action, which includes both antifungal and anti-inflammatory properties. However, its high cost and brand-only status mean it's usually prescribed after OTC options have failed.
Ertaczo is an effective prescription antifungal cream for treating athlete's foot, particularly for patients who haven't responded to over-the-counter treatments. Its dual mechanism of action — combining antifungal and anti-inflammatory effects — makes it a unique option in its class.
The biggest challenges with Ertaczo are its cost (up to $1,070 without discounts) and availability (not stocked at every pharmacy). If your doctor prescribes it, use savings tools and Medfinder to get the best price and find it in stock near you.
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