Debacterol is a topical chemical cautery agent used to treat canker sores (recurrent aphthous stomatitis) and minor oral ulcers by chemically sealing the wound and providing near-instant pain relief.

What Is Debacterol?

Debacterol is a topical oral treatment manufactured by Epien Medical. Its active ingredients are sulfonated phenolics and sulfuric acid (also known as phenolsulfonic acid and sulfuric acid). It is classified as an OTC medical device rather than an FDA-approved drug.

Unlike topical anesthetics that temporarily numb the area or antiseptics that target bacteria, Debacterol works through chemical cautery — it destroys the damaged cells at the ulcer site, including the nerve endings that transmit pain. This seals the ulcer and promotes faster healing. To learn more about the science behind it, see our post on How Does Debacterol Work?

Debacterol is available in two forms:

• Single-use applicator swabs — The most common consumer format
• Liquid solution in vials — Typically used in dental offices with cotton-tipped applicators

There is no true generic version of Debacterol. Oralmedic is an international brand with similar ingredients that may serve as a comparable alternative.

What Is Debacterol Used For?

Debacterol is primarily used for:

• Canker sores (recurrent aphthous stomatitis) — This is its primary indication. Canker sores are painful oral ulcers that appear inside the mouth on the cheeks, gums, tongue, or lips.
• Minor oral abrasions — Small cuts or irritations inside the mouth.
• Oral ulcers from braces or dental appliances — Friction from orthodontic hardware can cause ulcers that Debacterol can help treat.
• Traumatic oral ulcers — Ulcers caused by biting your cheek or tongue, or from hot food burns.

It is not intended for deep wounds, serious oral injuries, or conditions outside the mouth.

How Is Debacterol Applied?

Debacterol application is quick and straightforward, whether done at a dental office or at home:

1. Dry the ulcer. Use a cotton-tipped applicator to thoroughly dry the ulcerated area. This step is important for the product to work effectively.
2. Prepare the applicator. For swabs: bend the colored ring tip to snap the internal vial and release the liquid into the cotton tip. For vials: dip a cotton-tipped applicator into the solution.
3. Apply to the ulcer. Press the applicator to the dried ulcer for at least 5 seconds but no more than 10 seconds, using a rolling motion to cover the entire ulcer bed and rim.
4. Rinse immediately. Rinse your mouth thoroughly with water and spit. Do not swallow.

One application per ulcer is usually sufficient. Pain typically subsides almost immediately after rinsing. If pain returns, one repeat application may be done.

Who Should Not Use Debacterol?

Debacterol should not be used by people who have:

• A known allergy to sulfonated phenolics or sulfuric acid
• Deep wounds or serious oral injuries

Additionally:

• Children under 12: Debacterol has not been well-studied in young children. Consult a pediatric dentist before use.
• Pregnant or breastfeeding women: Limited data is available. Consult a healthcare provider before use.
• Do not swallow the solution under any circumstances.

How Much Does Debacterol Cost?

Debacterol typically costs $20 to $40 per box of single-use swabs. Pricing varies depending on the retailer and the number of swabs per box (typically 1 to 12 count).

Important cost details:

• Insurance coverage: Debacterol is generally not covered by health insurance since it is classified as an OTC medical device. Most patients pay out of pocket.
• FSA/HSA eligible: Some flexible spending accounts (FSA) and health savings accounts (HSA) may cover Debacterol. Check with your plan administrator.
• No manufacturer savings program: Epien Medical does not currently offer coupons or patient assistance programs for Debacterol.
• Oralmedic alternative: The international brand Oralmedic may be available online for approximately $15 to $30.

For more tips on reducing costs, see our post on How to Save Money on Debacterol.

Final Thoughts

Debacterol is a unique treatment for canker sores that offers something most other products cannot: near-instant pain relief through chemical cautery. While it can be harder to find than standard OTC remedies, many people who suffer from recurring canker sores consider it well worth the effort.

If you are having trouble locating Debacterol, Medfinder can help you find it in stock. You can also check our guide on How to Check If a Pharmacy Has Debacterol in Stock for additional search strategies.