Blisovi 21 Fe 1.5/30 Is a Combination Birth Control Pill Containing Norethindrone Acetate and Ethinyl Estradiol

Blisovi 21 Fe 1.5/30 28 Day Pack is a combination oral contraceptive (birth control pill) that contains two hormones — Norethindrone Acetate 1.5 mg and Ethinyl Estradiol 30 mcg — plus iron supplement tablets to take during your period week.

If you've been prescribed this medication or you're researching your options, this guide covers everything you need to know: what it is, what it's used for, how to take it, who should avoid it, and what it costs in 2026.

What Is Blisovi 21 Fe 1.5/30?

The Basics

• Generic name: Norethindrone Acetate and Ethinyl Estradiol Tablets, USP and Ferrous Fumarate Tablets
• Brand-name equivalent: Loestrin Fe 1.5/30 (now discontinued; generics like Blisovi Fe are widely available)
• Drug class: Combination oral contraceptive (estrogen + progestin)
• Manufacturer: Lupin Pharmaceuticals
• FDA status: FDA-approved generic oral contraceptive
• Controlled substance: No — Blisovi 21 Fe 1.5/30 is not a controlled substance

What's in Each Pack?

Every 28-day pack of Blisovi 21 Fe 1.5/30 contains:

• 21 active pink tablets: Each contains Norethindrone Acetate 1.5 mg (a progestin hormone) and Ethinyl Estradiol 30 mcg (an estrogen hormone)
• 7 brown tablets: Each contains Ferrous Fumarate 75 mg (iron). These are non-hormonal reminder pills — they help you stay on schedule and provide a small amount of iron during your period when iron loss is higher.

Other Generic Equivalents

Blisovi 21 Fe 1.5/30 is one of several FDA-approved generic versions of the same formulation. Others include:

• Junel Fe 1.5/30 (Teva Pharmaceuticals)
• Microgestin Fe 1.5/30 (Mayne Pharma)
• Larin Fe 1.5/30 (Novast Pharmaceuticals)
• Aurovela Fe 1.5/30
• Hailey Fe 1.5/30

All contain the same active ingredients at the same doses and are rated therapeutically equivalent by the FDA. Learn more about your options in our guide to alternatives.

What Is Blisovi 21 Fe 1.5/30 Used For?

Blisovi 21 Fe 1.5/30 is FDA-approved for two indications:

1. Prevention of pregnancy: When taken correctly, combination oral contraceptives are over 99% effective. With typical use (accounting for missed pills and other real-world factors), effectiveness is about 91%.
2. Treatment of moderate acne: In females at least 15 years old who have started menstruating and want to use oral contraceptives for birth control.

Doctors may also prescribe it off-label for:

• Regulating irregular menstrual cycles
• Reducing menstrual cramps (dysmenorrhea)
• Managing heavy menstrual bleeding (menorrhagia)
• Treating endometriosis symptoms
• Managing symptoms of polycystic ovary syndrome (PCOS)

How Is Blisovi 21 Fe 1.5/30 Taken?

Daily Schedule

1. Days 1-21: Take one pink (active) tablet at the same time every day
2. Days 22-28: Take one brown (iron) tablet at the same time every day
3. Day 29: Start a new pack immediately — do not skip any days between packs

When to Start

Your doctor will typically recommend one of two start methods:

• Day 1 Start: Take your first pink pill on the first day of your period. No backup contraception is needed.
• Sunday Start: Take your first pink pill on the first Sunday after your period begins. Use backup contraception (like condoms) for the first 7 days.

Important Tips

• Take the pill at the same time every day — setting a daily alarm helps
• Take with food if you experience nausea
• If you miss one active pill, take it as soon as you remember, then take the next pill at the regular time (you may take two pills in one day)
• If you miss two or more active pills, follow the detailed instructions in your pill package or call your provider
• If you miss any brown (iron) pills, simply throw them away and continue with the next day's pill — missing iron pills does not affect pregnancy protection

Who Should Not Take Blisovi 21 Fe 1.5/30?

Blisovi 21 Fe 1.5/30 is not safe for everyone. You should not take it if you have or have had:

• Blood clots (deep vein thrombosis, pulmonary embolism) or a history of blood clots
• Stroke or heart attack
• Coronary artery disease or cerebrovascular disease
• Breast cancer (current or history)
• Endometrial or other estrogen-dependent cancers
• Undiagnosed abnormal vaginal bleeding
• Liver disease, liver tumors, or hepatic adenomas
• Jaundice caused by pregnancy or prior birth control pill use
• Severe migraines with aura
• Uncontrolled high blood pressure

Smokers over 35: The FDA boxed warning states that women over 35 who smoke should not use combination oral contraceptives due to significantly increased risk of serious cardiovascular events.

For a full list of side effects and warning signs, see our dedicated guide.

How Much Does Blisovi 21 Fe 1.5/30 Cost?

With Insurance

Under the Affordable Care Act (ACA), most insurance plans must cover at least one generic oral contraceptive in each category at no cost to the patient. This means many women can get Blisovi 21 Fe 1.5/30 for $0 copay with insurance.

If your plan doesn't cover Blisovi specifically, ask your pharmacist about which equivalent generic (Junel Fe, Microgestin Fe, Larin Fe) is on your plan's formulary.

Without Insurance

The retail cash price for a one-month supply (28 tablets) ranges from approximately $35 to $90 depending on the pharmacy.

With Discount Coupons

Discount programs can significantly reduce your out-of-pocket cost:

• SingleCare: As low as $13 to $15 per month
• GoodRx: $15 to $25 per month at most pharmacies
• RxSaver and other discount cards: Comparable savings

For a complete guide to savings options, see How to Save Money on Blisovi 21 Fe 1.5/30.

Other Affordable Options

• Planned Parenthood: Offers birth control on a sliding fee scale based on income
• Title X clinics: Federally funded family planning clinics that provide contraception at low or no cost
• Telehealth services: Nurx, SimpleHealth, and The Pill Club often provide generic birth control for $0 with insurance or low flat fees without

Final Thoughts

Blisovi 21 Fe 1.5/30 28 Day Pack is a safe, effective, and affordable combination birth control pill used by millions of women. It's been on the market for years as a generic equivalent of Loestrin Fe 1.5/30, with multiple manufacturers producing the same formulation.

Understanding how it works, how to take it correctly, and what to watch for puts you in control of your reproductive health. If you need help finding it at a pharmacy near you, Medfinder can help you locate Blisovi 21 Fe 1.5/30 in stock quickly.